Clinical trials: Surgery of Breast Cancer
Breast Cancer
Feasibility in Identification of Breast Cancer Candidates for Elimination of Axillary Surgery
Preoperative identification of patients with pathologic complete response or residual disease in axilla can aid in tailoring subsequent axillary surgery including omission of axillary surgery based on tumor biology and response…
- Trial name
- NCT05663021
- Testing
- Ultrasound-guided core needle biopsy in breast
- Where
- China
- Volunteers
- 191 people
- Sponsor
- Fudan University
Pain
Acupuncture and Breast Cancer Rehabilitation
The patients were divided into two randomized groups with 24 patients per group, which were given weekly treatment for 10 weeks, one group treated with Kinesiotherapy lasting 30 minutes and the other group followed Kinesiotherapy…
- Trial name
- ACUP (NCT02691208)
- Testing
- Kinesiotherapy, Acupuncture
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Federal University of São Paulo
Sleep Quality
Effects of Biofeedback-based Music Program Using a Smart Device Application on Perioperative Sleep Quality
The purpose of this study is to investigate whether the effects of biofeedback-based music programs using a smart device application can improve perioperative sleep quality in patients undergoing breast cancer surgery.
- Trial name
- NCT05726162
- Testing
- biofeedback-based music program, Control
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Breast Cancer by AJCC V8 Anatomic Stage, Breast Cancer
De-escalation of Axillary Dissection for Node-positive Breast Cancer
Recent studies have demonstrated the safety of de-escalation of nodal surgery for clinically node-positive breast cancer patients after a favorable response to neoadjuvant systemic therapy (NST).
- Trial name
- NCT07856160
- Testing
- TAD+ALND
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Breast Cancer, Blood Loss, Surgical
Role of TXA in Patients Undergoing Breast Free Flap Reconstruction
Tranexamic acid (TXA) is a synthetic, competitive lysine receptor inhibitor on plasminogen. It ultimately stabilizes the fibrin matrix, therefore used as a hemostatic agent for various indications.
- Trial name
- NCT06428682
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Virginia
Neuropathic Pain, Postmastectomy Pain
Symptom Management After Breast Cancer Surgery
This trial is part of a larger, longitudinal study of symptoms that occur in the breast surgical scar area and/or ipsilateral arm following breast cancer surgery.
- Trial name
- NCT00686127
- Testing
- Lidoderm patch
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, San Francisco
Breast Cancer
Radiofrequency of Breast Cancers in Non Surgical Patients
To determine the efficacy and tolerance of ultrasonography (US)-guided percutaneous radiofrequency (RF) ablation with endocrine therapy in elderly patients with breast cancer who decline or are not candidates for surgery.
- Trial name
- RF-SEIN (NCT00210223)
- Testing
- ultrasonography (US)-guided percutaneous radiofrequency (RF) ablation with endocrine therapy
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Institut Bergonié
Breast Neoplasms
Trial of Tomotherapy in Breast Cancer
Tomotherapy is a new radiation therapy system that uses an integrated CT scanner during delivery of radiation treatment to improve the accuracy of the treatment.
- Trial name
- TomoBreast (NCT00459628)
- Testing
- Conventional radiotherapy, Tomotherapy
- Where
- Belgium
- Volunteers
- 118 people
- Sponsor
- Vrije Universiteit Brussel
Breast Cancer
Neo-RT: A Study Investigating Whether Changing the Sequence of Treatments (Starting Radiotherapy Followed by Hormone Therapy Before Surgery) is Feasible
Four in 10 women diagnosed with breast cancer undergo mastectomy with or without breast reconstruction and less than half are satisfied with how they look unclothed.
- Trial name
- Neo-RT (NCT03818100)
- Testing
- Intensity modulated radiotherapy (IMRT), Endocrine therapy, Breast conserving surgery
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- CCTU- Cancer Theme
Carcinoma Breast
Randomized Trial on Intraoperative Radiotherapy Full Dose Vs External Radiotherapy
The purpose of this study is to investigate the efficacy of exclusive intraoperative radiation therapy after conserving surgery in early-stage breast cancer compared with whole breast radiotherapy.
- Trial name
- ELIOT (NCT01849133)
- Testing
- external fractionated radiotherapy, intraoperative radiotherapy
- Where
- Italy
- Volunteers
- 1,305 people
- Sponsor
- European Institute of Oncology
Breast Cancer
Comparative Evaluation of Osteopathy Treatment Efficacy in Pain Support After Breast Surgery in Oncology
This is an open, prospective, controlled, randomized, comparative study with 2 arms. The purpose of the study is to assess the efficacy of osteopathy after breast surgery. 80 patients will be enrolled, 40 per arm.
- Trial name
- OSTEOPATHIE (NCT01403168)
- Testing
- OSTEOPATHY + conventional analgesic treatments, Conventional analgesic treatments
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Leon Berard
Analgesia
Erector Spinae Plane Block Versus General Anesthesia in Breast Cancer Surgeries
This study aims at comparing the analgesic efficacy and safety of bilevel erector spinae versus single level versus general anesthesia for breast cancer surgeries
- Trial name
- NCT05429489
- Testing
- Bilevel erector spinae plane block, Single level erector spinae plane block, Intravenous morphine
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer Female, Breast Cancer
Assessment of Oncological Safety, Quality of Life, and Environmental Impact of the Green Breast Surgery Protocol
Breast Cancer (BC) is the primary oncological diagnosis in women, with the annual incidence expected to exceed 3 million new cases by 2040 due to population growth and aging.
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Neoplasms
- Trial name
- BuGs (NCT06624917)
- Testing
- Green Breast Surgery Protocol
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Rome Tor Vergata
Breast Neoplasm Female
Breast Localization: RFID Tags vs Wire Localization
The RFID trial focuses on breast localization in patients with non-palpable breast cancers. It aims to demonstrate the improvement in patient comfort when using the Radio Frequency Identification (RFID) tag and LOCalizer™ device…
- Trial name
- RFID (NCT04750889)
- Testing
- RFID tags, Wire localization
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Jean Perrin
Breast Cancer
Breast Surgery Recovery: The Clinical and Psychosocial Impact of THEYA Recovery Range
A randomised interventional comparative control study will be undertaken to compare the THEYA Recovery Range postoperatively for patients undergoing wider lumpectomies, partial mastectomies and total mastectomies to current…
- Trial name
- NCT02593890
- Testing
- THEYA Recovery Range
- Volunteers
- 100 people
- Sponsor
- Claire Kelly
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer
This phase II trial investigates the safety of delivering a part (boost) of radiation treatment before breast surgery in treating patients with breast cancer that has not spread to other places in the body (non-metastatic).
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8
- Trial name
- NCT04871516
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Radiation Boost
- Where
- 11 sites in United States
- Volunteers
- 103 people
- Sponsor
- Rutgers, The State University of New Jersey
Postoperative Pain, Chronic Post Operative Pain
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
The present study compares the Erector Spinae Plane (ESP) block, Pectoral (PECS II) block, and Serratus-Intercostal Fascial Plane (SIFP) block.
- Conditions
- Postoperative Pain, Chronic Post Operative Pain, Breast Tumor, Locoregional Anesthesia
- Trial name
- NCT05185752
- Testing
- SIFP Block Locoregional Interfascial Anesthesic Technique, PECS II block: Locoregional Interfascial Anesthesic Technique, ESP block: Locoregional Interfascial Anesthesic Technique
- Where
- Spain
- Volunteers
- 103 people
- Sponsor
- University of Valencia
Breast Cancer
Chemotherapy With or Without Bevacizumab in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer That Can Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00408408
- Testing
- bevacizumab, capecitabine, cyclophosphamide
- Where
- 442 sites in United States, Canada and 1 more
- Volunteers
- 1,206 people
- Sponsor
- NSABP Foundation Inc
The Role of Multimedia on Retention and Comprehension of Key Concepts for Surgical Options in Newly Diagnosed Breast Cancer Patients.
Evaluation of the Use of Multimedia to Enhance Patient and Family Understanding
This study will investigate the potential impact of arts-informed, technology-based patient education material, and specifically, the role of multimedia imagery on patient comprehension, perceived satisfaction, anxiety levels…
- Trial name
- NCT01152775
- Testing
- This group of patients will be exposed to multimedia, No Media
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Breast Neoplasms, Anesthesia
Single Versus Multiple Injection Ultrasound Guided Paravertebral Blocks
Paravertebral block (PVB) has been shown to provide excellent analgesia for major breast surgeries resulting in reduced narcotic consumption, reduced nausea, improved quality of recovery, reduced chronic pain and possibly reduced…
- Trial name
- NCT02852421
- Testing
- Single injection paravertebral block, Multiple injection paravertebral blocks
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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