Clinical trials: Surgery of Breast Cancer
Breast Cancer
Clinical Trial Comparing Outcomes of Breast Conserving Operations With Classic v High-frequency Electrocoagulation
The aim of this study is to assess the outcomes of breast conserving therapy operation depending on the type of surgical tool used: classic electrocoagulation with higher operative temperatures and high frequency…
- Trial name
- NCT01216254
- Testing
- classic v high-frequency electrocoagulation
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Breast Neoplasms
Effects of a Telerehabilitation Intervention in the Management of Complications After Breast Cancer Surgery
The most common complaints after breast surgery are postoperative pain reported in up to 68% of patients, musculoskeletal problems in the shoulder and functional limitations in up to 59% of patients after mastectomy and…
- Trial name
- LINFO (NCT06608446)
- Testing
- Telerehabilitation, Standard Care
- Where
- Italy
- Volunteers
- 155 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Breast Cancer Lymphedema
Axillary Reverse Mapping (ARM) in Breast Cancer Surgery to Prevent Lymphedema. (ARMtrial)
Breast cancer related lymphedema (BCRL) is a debilitating and distressing condition affecting approximately one out of five breast cancer survivors.
- Trial name
- NCT03333226
- Testing
- Axillary Reverse Mapping (ARM)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University Hospital of Ferrara
Breast Cancer, Quality of Life
The PreQ-20 TRIAL, a Prospective Cohort Study of Patients Undergoing Prepectoral Breast Reconstruction
The investigators conducted a prospective cohort study to assess the safety, quality of life and cosmetic sequelae of prepectoral breast reconstruction in women with breast cancer and high risk.
- Conditions
- Breast Cancer, Quality of Life, Surgery--Complications
- Trial name
- PreQ-20 (NCT04642508)
- Testing
- Prepectoral reconstruction
- Where
- Spain
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospital A Coruña
Breast Cancer
Therapy With Bevacizumab (BEV), Doxorubicin, and Cyclophosphamide Followed by BEV, Docetaxel, and Capecitabine Before Surgery Followed by BEV Alone After Surgery for Women With Locally Advanced Breast Cancer
Bevacizumab is an angiogenesis inhibitor which means it works to stop blood vessel formation in tumors. Without new blood vessels, the growth of a tumor is slowed. Chemotherapy drugs kill cancer cells more directly.
- Trial name
- NCT00365417
- Testing
- Bevacizumab, Doxorubicin, Cyclophosphamide
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- NSABP Foundation Inc
Breast Cancer
Neoadjuvant Epirubicin, Cyclophosphamide, and Paclitaxel With or Without Gemcitabine in Treating Women Who Are Undergoing Surgery for Early Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as epirubicin, cyclophosphamide, paclitaxel, and gemcitabine use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00070278
- Testing
- cyclophosphamide, epirubicin hydrochloride, gemcitabine hydrochloride
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Breast Image Scale Index for Self Esteem Evaluation, Breast Symmetry Index
Prospective Non-randomized Evaluation of Oncoplastic Surgery
Breast conserving therapy (BCT) is the standard treatment for intraductal or invasive breast cancer patients. However cosmetic results, e.g. symmetry and nipple displacement, are sometimes poor reducing the quality of life.
- Conditions
- Breast Image Scale Index for Self Esteem Evaluation, Breast Symmetry Index, Quality of Life, Morbidity
- Trial name
- iTOP (NCT01396993)
- Testing
- Breast Surgery
- Where
- Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Breast Cancer
Effect of Perioperative Low Dose Ketamine on Postoperative Recovery in Patients Undergoing Breast Cancer Surgery
Breast cancer patients often have perioperative emotional disorders such as anxiety and depression, which can lead to poor quality of recovery.This study aims to determine whether ketamine could improve the quality of recovery in…
- Trial name
- NCT03676114
- Testing
- ketamine, Normal saline
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Han Yuan
Breast Cancer Surgery Pain
Postoperative Analgesic Consumption After Preoperative Gabapentin vs Placebo in Breast Cancer Surgery
The study will be conducted after approval from the Scientific and Ethical Review Committees. Eligible patients will be enrolled after obtaining written informed consent and randomly allocated to Group A (gabapentin) or Group B…
- Trial name
- NCT07804784
- Testing
- Oral Gabapentin pre-op, Vitamin B complex tablets (Neurorubine TM -Forte Lactab TM)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Breast Cancer Invasive
Intra-operative Detection of Positive Margins and Lymph Nodes in Breast Surgery
In this project, the investigators will develop novel optical coherence tomography (OCT)-Raman spectroscopy and autofluorescence (AF)-Raman spectroscopy systems based on a selective sampling approach optimised for high-resolution…
- Trial name
- NCT06977698
- Testing
- OCT-Raman, AF-Raman
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Early Stage Breast Carcinoma
Observational Trial on the Impact of Hypnose Used as a Sedation in Oncology Surgery in Breast Cancer
The investigators will compare the operated patients for a beginning breast cancer in the Hypnose arm and the patient in the classical general anesthesia arm.
- Trial name
- NCT03003611
- Testing
- hypnose sedation, general anesthesia
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Breast Cancer
Accelerated Hypofractionated Radiotherapy (AHF-RT) for the Treatment of Breast Cancer
The goal of this study is to explore the safety, effectiveness, quality of life, and cost effectiveness of accelerated hypofractionated radiotherapy (AHF-RT) as treatment after lumpectomy in patients with early stage breast…
- Trial name
- NCT01278212
- Testing
- accelerated hypofractionated radiotherapy (AHF-RT)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Louisville
Breast Cancer
Mini-invasive Detection of Residual Disease in Breast Cancer Patients in Remission After Primary Chemotherapy
Breast surgery may be overtreatment when there is a complete response to systemic neoadjuvant treatment as determined clinically and by imaging.
- Trial name
- NCT05951699
- Testing
- minimally invasive preoperative image-guided vacuum-assisted biopsy
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Breast Conserving Surgery, Endoscopic Surgery
Single Port Endoscopic Breast Conserving Surgery
The center plans to carry out a prospective clinical study of single hole total endoscopic breast conserving surgery for early breast cancer compared with open breast conserving surgery, to provide high-level evidence-based…
- Trial name
- NCT06593132
- Testing
- endoscopic breast conserving surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Ren,Yu
Breast Neoplasms
DFS and QOL After Modified Radical Mastectomy vs. Expanded Mckissock Surgery for EIC of the Breast
Extensive intraductal carcinoma of the breast refers to a type of breast cancer in which ≥ 25% of ductal carcinoma in situ is present in invasive tumors and there is a scattered distribution of ductal carcinoma in situ (DCIS) in…
- Trial name
- NCT04052893
- Testing
- Expanded Mckissock surgery, Modified radical mastectomy
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Radiation Therapy After Surgery in Treating Women With Early Stage Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which regimen of radiation therapy is more effective following surgery for breast cancer.
- Trial name
- NCT00005587
- Testing
- radiation therapy
- Where
- 32 sites in United Kingdom
- Sponsor
- Medical Research Council
Breast Cancer, Prehabilitation
IMpact of PRehabilitation in Oncology Via Exercise - Breast Cancer
The purpose of this study is to determine whether patients are able to participate in a so called prehabilitation program (prior to the beginning of cancer treatment) which includes (1) a supervised and home-based exercise…
- Conditions
- Breast Cancer, Prehabilitation, Physical Activity, Surgery
- Trial name
- IMPROVE-B (NCT03498157)
- Testing
- Exercise, Prehabilitation Education
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Milton S. Hershey Medical Center
Breast Cancer
Randomized Short-term Pre-surgical Study to Assess the Effects of Abemaciclib (LY2835219) in Early Breast Cancer Patients
Cyclins CDK4 / 6 are extensively involved in the proliferation and growth of numerous cancers including breast cancer. The objective of this study is to identify if a new preoperative oral treatment, abemaciclib directed against…
- Trial name
- ABC-POP (NCT02831530)
- Testing
- Abemaciclib
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Cognitive/Functional Effects, Recurrent Breast Cancer
Vascular and Cognitive Assessments in Patients With Breast Cancer Undergoing Chemotherapy After Surgery
This clinical trial studies vascular and cognitive assessments in patients with breast cancer undergoing chemotherapy after surgery.
- Conditions
- Cognitive/Functional Effects, Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer
- Trial name
- NCT01483196
- Testing
- ultrasound imaging, questionnaire administration, assessment of therapy complications
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer
Pecs II Block and PaB Could be an Alternative in Breast Surgery
The association between ultrasound-guided Pecs II block and parasternal block can represent a valid alternative in the management of acute and postoperative pain syndrome after quadrantectomy with or without axillary dissection.
- Trial name
- NCT02865265
- Testing
- Pecs II and parasternal blocks
- Volunteers
- 180 people
- Sponsor
- Emiliano Petrucci
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