Clinical trials: Surgery- Complications
Pain, Postoperative, Postoperative Nausea and Vomiting
A Comparison of Tumescence in Breast Reduction Surgery
The investigators' main hypothesis is that in breast reduction surgery, the use of tumescent solution containing both dilute lidocaine and epinephrine will lead to better control of postoperative pain, nausea, vomiting, shorter…
- Trial name
- NCT01602692
- Testing
- Tumescent solution with dilute lidocaine and epinephrine, Tumescent Solution with dilute epinephrine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Pain, Complications
Comparison of Two Kinds of Postoperative Analgesia After Amputation
Pain after amputation is a significant problem among amputees. Phantom limb pain may appear in up to 85% of patients and is usually resistant to a wide variety of treatments.It is believed that regional anesthesia, by preventing…
- Trial name
- NCT02114463
- Testing
- Local analgesic, Intravenous analgesic, ropivacaine
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Perfusion, Perioperative/Postoperative Complications
The Effect of Trendelenburg Position on CCA Blood Flow
The investigators will evaluate the change of the common carotid artery blood flow according to patient's position and penumoperitoneum.
- Trial name
- NCT04233177
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cesarean Section, Cicatrix
Subcuticular Suture Versus Staples for Closure of the Skin After Caesarean Section.
The Purpose of this study is to compare two methods for closure of the skin after caesarean section on the same patient; staples and subcuticular sutures. The study is performed on two separate groups of patients: 1.
- Trial name
- NCT01217567
- Testing
- Staples left, subcuticular suture right, Subcuticular suture left side and staples right
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Gynecologic Disease, Cosmesis
Comparison of Cosmesis, Patient Satisfaction and Quality of Life in Patients Undergoing Laparoscopic Surgery
To compare robot assisted versus conventional laparoscopic surgery performed for bening gynecologic disorders regarding cosmesis, patient satisfaction and quality of life
- Conditions
- Gynecologic Disease, Cosmesis, Patient Satisfaction, Quality of Life
- Trial name
- NCT04064216
- Testing
- Laparoscopic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Postoperative Pain
Postoperative Pain Relief After Major Abdominal Gynecological Surgery
The aim of our study was to compare the effects of Lomber Epidural Analgesia (LEA), Transversus Abdominis Plane (TAP) block and Local Anesthetic Infiltration (LAI) on postoperative morphine consumption, time to first recue…
- Trial name
- NCT05845385
- Testing
- lumbar epidural analgesia with bupivacaine, transversus abdominis plane block with bupivacaine, wound infiltration with bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Opioid Consumption, Postoperative, ESPB
Evaluation of the Postoperative Efficacy of Bilateral Lumbar Erector Spinae Plane Block (ESPB) in Patients Undergoing Lumbar Disc Herniation Repair Surgery
This prospective observational study aims to evaluate the efficacy of bilateral lumbar erector spinae plane (ESP) block in providing effective postoperative analgesia and its potential impact on early mobilization and length of…
- Conditions
- Opioid Consumption, Postoperative, ESPB, Postoperative Pain, Plane Blocks
- Trial name
- NCT07403734
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Surgical Site Infection, Surgical Wound Infection
Floraseal Versus Iodine Impregnated Adhesive Drapes
Infection after total joint arthroplasty can have devastating consequences. Adhesive drapes have been traditionally used at our institution to help reduce the risk of wound contamination and infection by superficial skin flora.
- Trial name
- NCT03466489
- Testing
- Floraseal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Postoperative Pain, Ambulatory Surgery
Comparison Between Pre-operative Prescription Delivered During Anesthesia Consultation or Post-operative Prescription
This study evaluates the comparison of the incidence of postoperative home pain after ambulatory surgery with general anesthesia between a group with pre-surgical prescription delivered during anesthesia preoperative clinic and a…
- Conditions
- Postoperative Pain, Ambulatory Surgery, Anesthesia, Postoperative Complication
- Trial name
- AMBUPRESS (NCT03205189)
- Testing
- Comparison between pre-operative prescription and post-operative prescription
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Post Operative Pain
Dexamethasone or Dexmedetomidine as Adjunct in Fascia Iliaca Block During Positioning for Sub-arachnoid Block & Post-operative Analgesia After Femur Neck Fracture Surgery: A Randomized Control Trial
Femur fracture is a common injury occurring in the young due to trauma as well as amongst the elderly due to fall. Reduction and fixation of femur fractures pose a challenge to the anesthesiologist.
- Trial name
- NCT05484648
- Testing
- Dexamethasone, Dexmedetomidine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Inflammatory Bowel Diseases
Preoperative Oral ImmunoNuTrition to Improve Surgical Outcomes for IBD Patients (PINT)
The central focus of this trial is to understand the effectiveness of Preoperative Immunonutrition (PINT) in improving surgical outcomes for patients with inflammatory bowel disease (IBD).
- Trial name
- PINT (NCT03333148)
- Testing
- Nestle IMPACT Immunonutrition, Arm B- Standard of Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Delirium, Bypass Complication
Care Bundle's Impact on Delirium Prevention in CABG Patients
This research investigates the effectiveness of a care package used in the care of patients undergoing coronary artery bypass graft (CABG) surgery in preventing postoperative delirium.
- Conditions
- Delirium, Bypass Complication, Coronary Artery Bypass, Patient Care Bundles
- Trial name
- CareBundle (NCT06036017)
- Testing
- Earplugs, Music Therapy, Presence of Family After Extubation:
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- İslam Elagöz
Urologic Diseases
Effect of Prewarming During Induction of General Anesthesia Combined With Warmed Intravenous Fluid on Core Temperature.
Hypothermia occurs frequently during general anesthesia. This study is to evaluate the efficacy of 10 minutes of prewarming during induction of general anesthesia during urologic surgery.
- Trial name
- NCT05636189
- Testing
- warming during induction of anesthesia, Prewarmed intravenous fluid administration
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Inje University
Surgical Site Infections, Stress Hyperglycemia
Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications
This study is to determine if glucose monitoring and treatment in surgical procedures over 2 hours help to decrease the surgical site infection risk and reduce postoperative complications.
- Trial name
- POGM (NCT06765655)
- Testing
- Insulin Lispro Injection, glucose testing
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- St. Peter's Hospital, Albany, NY
Esketamine, Pregabaline
Esketamine Combined With Pregabalin on CPSP in Spinal Patients.
Chronic postsurgical pain has become one of the most common complications of surgery. The quality of life will be impacted once the postsurgical patients are combined with persistent pain.
- Conditions
- Esketamine, Pregabaline, Chronic Post Operative Pain
- Trial name
- NCT06117917
- Testing
- S-ketamine and pregabalin
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Third Molars Extraction
The Use of Advanced Platelet-rich Fibrin in Mandibular Third Molar Surgery
The purpose of the study is to quantify the levels of platelets and inflammatory markers in A-PRF from a standard venous whole blood sample, and to evaluate the effect of A-PRF on postoperative discomfort and complications…
- Trial name
- NCT07761338
- Testing
- Third molar
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Skin Diseases, Surgical Site Infection
Effectiveness of Preoperative Surgical Scrubbing Using Clorhexidine Digluconate and Parachlorometaxylenol (ECP)
Despite the wide variety of products and antiseptic agents, no agent is ideal for every situation. The investigators would like to evaluate the difference in reducing bacterial load, using 4% chlorhexidine digluconate and 3%…
- Trial name
- ECP (NCT02500758)
- Testing
- Preparatory handwash, Preoperative surgical scrubbing using 3% PCMX, Preoperative surgical scrubbing using 4% CHG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ricardo Becerro de Bengoa Vallejo
Postoperative Nausea and Vomiting, Scoliosis
A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery
The aim of this clinical trial is to compare the effectiveness of two Serotonin (5- HT3) receptor antagonist, palonosetron and granisetron, administered along with dexamethasone as a preventive measure against early and delayed…
- Trial name
- PONV (NCT06540885)
- Testing
- Palonosetron (Group P), Granisetron (Group G)
- Where
- 2 sites in Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Plugs in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) plugs help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07484997)
- Testing
- Concentrated Growth Factor (CGF) Plug
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery
Near Infrared Spectroscopy for the Detection of Acute Kidney Injury in Children Following Cardiac Surgery
One in a hundred children is born with a heart defect. Some children require heart surgery within the first few days of life, while others can wait until they are older.
- Conditions
- Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery, Children
- Trial name
- NCT01382758
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
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