Clinical trials: Surgical
Frailty, Thoracic Surgery
A Frailty-specific Prehabilitation Program for Mild to Moderately Frail Patients Undergoing Cardiac Surgeries/Procedures
The purpose of this study is to investigate the effects of the frailty-specific prehabilitation program on functional capacity, frailty, cardiac-specific functional status, serum albumin level, high-sensitivity C-reactive protein…
- Trial name
- NCT07824700
- Testing
- Frailty-specific prehabilitation program
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- The University of Hong Kong
Plantar Fascitis, Fat Pad Syndrome
Offloading Device for Post Surgical Foot Procedures
Study goals are to determine if a novel post-surgical foot offloading device can reduce post-operative pain and expedite the return to daily activity following fat grafting.
- Trial name
- NCT03873207
- Testing
- PopSole™ offloading device, padded insole
- Where
- United States
- Sponsor
- Jeffrey A. Gusenoff, MD
Amputation; Traumatic, Leg, Lower
Transtibial Osseointegration
Purpose: Aim 1: Quantify soft tissue complications and infections of service members with transtibial amputations treated with OPRA OI and compare them to transfemoral OI service members.
- Trial name
- TOSS (NCT06636136)
- Testing
- OPRA
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Walter Reed National Military Medical Center
Dental Implants, Tooth Loss
Immediate Load in Dental Implants Using Conventional Drilling and Piezoelectric Osteotomy on Aesthetic Zone.
Compare the survival rate of the implants placed using the ultrasonic technique and placed using conventional drilling, with an immediate load on the aesthetic zone.
- Trial name
- NCT04497571
- Testing
- Piezoelectric osteotomy., Conventional drilling
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Patient Depression, Anxiety, Stress and Pain
The Effect of Listening to Holy Quran Recital on Depression, Anxiety and Stress Post CABG
Coronary artery bypass graft (CABG) is one of the most common surgical treatments for coronary artery disease. CABG has many beneficial outcomes for patients.
- Trial name
- NCT05419544
- Testing
- Holy Quran Recital effect
- Where
- 2 sites in Jordan
- Volunteers
- 128 people
- Sponsor
- Applied Science Private University
Intraoperative Hypotension
Advanced Cardiovascular Management in Major Non-cardiac Surgery.
This is a single center, randomised and controlled clinical triaI whose aim is to predict and treat in advance, intraoperative hypotension episodes.
- Trial name
- NCT07134530
- Testing
- HPI-driven intraoperative hemodynamic management strategy, GDT strategy
- Where
- Italy
- Volunteers
- 534 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Lumbar Spinal Stenosis
Quantitative Evaluation of Motor Function Before and After Surgery for Degenerative Lumbar Spinal Stenosis
Low back pain is a leading cause of medical consultations in France and in other industrialized countries. Although spinal surgery is a recognized treatment, to date, its impact has only been assessed using subjective or…
- Trial name
- SPEED (NCT03194607)
- Testing
- Functional walk tests, 3D analysis of locomotion and posture, questionnaires
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Intracranial Aneurysm, Transradial Access(TRA)
Application of Brachial Plexus Block in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach
The aim of this study was toinvestigate the effect of BPB on outcome of upper extremity arteries in patients undergoing interventional embolization of intracranial aneurysms via TRA.
- Trial name
- ABPBCAETRA (NCT06035692)
- Testing
- Ropivacaine
- Where
- China
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Obesity
Harmonic Versus Electro Surgery in Lower Body Lift Procedures
The objective of this study is to determine if the use of The Harmonic™ (an ultrasonic surgical instrument) in Lower Body Lift procedures reduces volume and duration of wound drainage after surgery when compared to Electro…
- Trial name
- LBL (NCT00522171)
- Testing
- The Harmonic™ ultrasonic scalpel
- Where
- 2 sites in United States, Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery
Physiological Stress
Physiologic Burden to the Surgeon During Orthopaedic Surgery
The investigator's plan to quantify the physiologic impact of orthopaedic surgery on the surgeon and operating team.
- Trial name
- NCT06180044
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Utah
Soft Tissue Sarcoma (Excluding GIST), Soft Tissue Sarcoma Adult
Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma
The purpose of the study is to investigate whether a personalized selection of patients with localized soft tissue sarcoma for preoperative proton radiation therapy can reduce long-term radiation side effects without increasing…
- Conditions
- Soft Tissue Sarcoma (Excluding GIST), Soft Tissue Sarcoma Adult, Soft Tissue Sarcoma of the Trunk and Extremities, Synovial Sarcomas
- Trial name
- PROSARC-1 (NCT07169344)
- Testing
- preoperative, Quality of life, Functional outcome
- Where
- 4 sites in Norway
- Volunteers
- 110 people
- Sponsor
- Oslo University Hospital
Elbow Dislocation, Heterotopic Ossification
Tranexamic Acid Prophylaxis for Heterotopic Ossification in Elbow Fracture-Dislocation Surgery
Heterotopic ossification (HO) following elbow fracture-dislocation is a well-recognized condition that can lead to reduced range of motion, increased pain, and the necessity for repeat surgeries.
- Trial name
- NCT06088407
- Testing
- with Tranexamic acid
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Thrombosis
STRATAGEM: Strategy for Managing Antiplatelet Therapy in the Perioperative Period of Non Coronary Surgery
The STRATAGEM trial is an investigator-driven French nationwide multicenter, randomized, double-blind, placebo-controlled trial comparing perioperative low-dose aspirin therapy versus placebo in the perioperative period in…
- Trial name
- STRATAGEM (NCT00190307)
- Testing
- aspirin 75 mg/day
- Where
- France
- Volunteers
- 293 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oral Health
A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients
Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or…
- Trial name
- NCT06969092
- Testing
- Oral Frailty
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Blood Loss
Tranexamic Acid for Unilateral Total Knee Arthroplasty
Total knee arthroplasty is often associated with excessive postoperative bleeding due to increased fibrinolysis. Hence, the objective of the proposed of this multicentre study is to determine the peri-operative bleeding comparing…
- Trial name
- TRANEXTOP (NCT01594671)
- Testing
- Tranexamic Acid, haemostasia
- Where
- 2 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Craniosynostoses, Pain, Postoperative
Scalp Block Decreases Pain and Side Effects
Postoperative analgesia after corrective surgery of paediatric craniosynostosis is crucial in term of short and long-term outcomes.
- Trial name
- NCT04133467
- Testing
- scalp block
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Colon Neoplasms, Crohn Disease (CD)
Feasibility Study of the SEGER Device in Laparoscopic Gastrointestinal Surgery
This is a first-in-human feasibility study designed to evaluate the safety and performance of the SEGER device in patients undergoing elective laparoscopic gastrointestinal surgery requiring intracorporeal anastomosis.
- Conditions
- Colon Neoplasms, Crohn Disease (CD), Obesity & Overweight
- Trial name
- SEGER-FIH (NCT07508592)
- Testing
- SEGER Device
- Where
- El Salvador
- Volunteers
- 10 people
- Sponsor
- Seger Surgical Solutions
Vital Sign Monitoring, Post Operative Complications
Continuous Vital Sign Monitoring Versus Routine Spot-checks in Patients After Non-cardiac Surgery
The "COME ON, NOW!" trial is a randomized, single-center trial in patients recovering from non-cardiac surgery on normal wards investigating whether continuous vital sign monitoring - compared to routine spot-checks by nurses …
- Conditions
- Vital Sign Monitoring, Post Operative Complications, Non-cardiac Surgery, RCT
- Trial name
- COME ON NOW (NCT07385092)
- Testing
- Unblinded continuous vital sign monitoring, Blinded continuous vital sign monitoring
- Where
- Germany
- Volunteers
- 264 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Lung Diseases
Continuous Erector Spinae Plane Block or Thoracic Epidural Analgesia Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960736
- Testing
- ESP block (Group A), TEA group (Group B)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Bradycardia
Brad Arrhythmia Induced by Repeated Succinylcholine During Gynecological Laparoscopic Surgery
Cardiac arrhythmias are a well-recognized complication of anesthesia for laparoscopy. The aim of this study was to evaluate the efficacy of atropine sulfate for prevention of brad arrhythmia induced by repeated succinylcholine…
- Trial name
- NCT02676011
- Testing
- IM atropine, IV atropine, Atropine mixed with second dose succinylcholine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.