Clinical trials: Surgical Approach
Laparoscopic Surgery, Colorectal Cancer
Laparoscopic Approach for Emergency Colon Resection
This is a randomized, controlled, parallel, multicenter trial to compare post-operative complications and long-term results between open and laparoscopic technique in emergency colorectal surgery.
- Conditions
- Laparoscopic Surgery, Colorectal Cancer, Colorectal Disorders, Emergencies
- Trial name
- NCT05005117
- Testing
- Laparoscopic operation, Open operation
- Where
- Finland
- Volunteers
- 192 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Femoral Neck Fractures, Bone Mineral Density
Surgical Approach in Hemiarthroplasty. A Randomized Clinical Trial Comparing Posterior and Anterior Approach
Dislocated femoral neck fractures are routinely treated with cemented hemiartroplasty and the direct lateral approach (Hardinge) has commonly been used in Norway.
- Conditions
- Femoral Neck Fractures, Bone Mineral Density, Muscle Damage, Surgical Approach
- Trial name
- NCT04900506
- Testing
- Posterior SPAIRE approach, anterior approach
- Where
- 2 sites in Norway
- Volunteers
- 210 people
- Sponsor
- Sorlandet Hospital HF
Sciatic Nerve AH, Peripheral Nerves US
Ultrasound Description of the Sciatic Nerve
Sciatic nerve blocks are frequently used for anesthesia or analgesia for surgery of the lower legs. Currently, if ultrasound is used to find the sciatic nerve, the leg must be raised to locate the nerve with the ultrasound probe…
- Trial name
- NCT00663715
- Testing
- Observation of the Sciatic Nerve
- Sponsor
- Children's Hospital of Philadelphia
Chronic Kidney Diseases
New Approach of Loco Regional Analgesia in Kidney Transplant
Kidney transplant is considered as a moderate painful surgery. Unfortunately, patients with chronic kidney disease are not able to degrade opioid drugs and are therefore most likely to be subjected to the secondary effects of…
- Trial name
- CARRENAL (NCT05391451)
- Testing
- efficacy of quadratus lumborum block in post-operative analgesia in kidney transplant surgery, general anesthesia
- Where
- France
- Volunteers
- 48 people
- Sponsor
- CHU de Reims
Central Venous Catheterization
Comparison of the Oblique-axis and Long-axis Approaches for Axillary Vein Catheterization Under Ultrasound Guidance
Ultrasound-guided axillary vein catheterization can be performed via the oblique-axis and long-axis approaches of the axillary vein.
- Trial name
- NCT04962945
- Testing
- Oblique-axis approach group, Long-axis approach group
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Guowei Tu
Osteoarthritis, Rheumatoid Arthritis
Minimally Invasive Versus Conventional Approaches in Navigated Total Knee Arthroplasty (TKA)
50 patients are randomized to two groups who receive a navigated knee prosthesis. Aim of the study is a comparison between a minimally invasive and a conventional approach.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis
- Trial name
- NCT00839020
- Testing
- Navigated TKA with a minimally invasive approach, Navigated TKA with a conventional approach
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Aesculap AG
Lung Cancer, Robotic Thoracic Surgery
Impact of Robotic Approach Compared to VATS and Open Approach on Quality of Life in Patients With Lung Cancer
The aim of the study is to compare quality of life and early and late post-operative pain after anatomical lung resection (lobectomy or segmentectomy) performed by a robotic approach compared to the videothoracoscopic approach…
- Conditions
- Lung Cancer, Robotic Thoracic Surgery, Video-assisted Thoracis Surgery (VATS), Open Thoracotomy Surgery
- Trial name
- QoL (NCT04353349)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Clinico Humanitas
Renal Cell Carcinoma
Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma
Through the neoadjuvant treatment with a combination of Pucotenlimab and Lenvatinib, it eventually enables the successful and safe implementation of partial nephrectomy in patients with localized renal cancer, who have…
- Trial name
- NCT06129955
- Testing
- Pucotenlimab Combined With Lenvatinib
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Sun Yat-sen University
Compare Two Surgical Approaches Used in Total Hip Arthroplasty
Short-term Results of SuperPATH Versus Direct Lateral Approach In Primary Total Hip Arthroplasty: A Randomized Controlled Study.
Total hip arthroplasty (THA) has shown great success in relieving joint pain and disability and has been a procedure of choice for the treatment of end-stage degenerative joint diseases and trauma.
- Trial name
- NCT07633925
- Testing
- Surgical approaches: direct lateral approach for the hip and SuperPATH approach
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Breast Cancer
Safety and Aesthetic Outcomes of Breast Conserving Surgery With Peri-areolar Incision Approach
Cosmetic result after breast-conserving surgery (BCS) would impose great effect upon patient's quality of life. Although peri-areolar incision has been widely used in benign breast tumor excision, mastopexy procedures and…
- Trial name
- NCT01412788
- Testing
- peri-areolar incision, traditional incision
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Injury Arm
Comparison of the Onset Times and Durations of Actions of Different Local Anesthetic Mixture Solutions [CODLAM]
Objective To investigate the onset times and duration of local anesthetic mixture solutions used for axillary-supraclavicular brachial plexus blocks and to compare the quality of anesthesia in patients with trauma of the upper…
- Trial name
- CODLAM (NCT03454789)
- Testing
- brachial plexus block for LB Group, brachial plexus block for BS Group, brachial plexus block for LS Group
- Volunteers
- 85 people
- Sponsor
- University of Pecs
Critical Lower Limb Ischemia
Surgical Bypass Versus Hybrid Approaches for Critical Limb Ischemia
The present randomized study proposed to compare the immediate postoperative and 2-year clinical outcomes of long surgical bypass and hybrid approaches in patients with multilevel critical lower limb ischemia.
- Trial name
- NCT04490408
- Testing
- long surgical bypass, Hybrid approach
- Volunteers
- 52 people
- Sponsor
- Egyptian Biomedical Research Network
Anesthesia, Regional, Brachial Plexus Block
Comparison of the Infraclavicular and Axillary Approaches for Continuous Ultrasound-guided Brachial Plexus Block.
Prospective randomized study comparing the axillary and the infraclavicular approaches for continuous brachial plexus block after hand surgery.
- Trial name
- ICAX (NCT04053491)
- Testing
- Hand surgery under regional anesthesia
- Sponsor
- University Hospital, Bordeaux
Ovarian Cancer
Ovarian Cancer Radiomics Approach in CT Led Evaluation
When patients have suspected or confirmed ovarian cancer standard treatment will involve surgery and chemotherapy. However, as with any treatment, it is challenging to predict treatment response in advance.
- Trial name
- ORACLE (NCT06817174)
- Where
- United Kingdom
- Volunteers
- 168 people
- Sponsor
- Imperial College Healthcare NHS Trust
Thyroid Cancer, Mediastinal Diseases
Lateral Approach for Mediastinal Lymph Node Dissection in Thyroid Cancer
Despite the numerous surgical approaches available for superior mediastinal lymph node dissection in thyroid cancer, many of these methods still have significant limitations.
- Conditions
- Thyroid Cancer, Mediastinal Diseases, Lymph Node Metastasis
- Trial name
- NCT06793579
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Chongqing General Hospital
Atrial Fibrillation (AF)
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)
The purpose of the PAUSE-Virtual Study is to show that by changing pre-surgery visits with patients taking a blood thinner (direct oral anticoagulant (apixaban, dabigatran, edoxaban, rivaroxaban or warfarin) when the participant…
- Trial name
- PAUSEVirtual (NCT06844227)
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 1,780 people
- Sponsor
- McMaster University
Transmuscular Quadratus Lumborum Block Hip Surgery
A Novel Approach for Transmuscular Quadratus Lumborum Block
a novel approach for TQL (anterior Q.L) block aiming mainly for terminal branches of lumbar plexus. The technique is described as Para-Spinous Saggital Shift Q.L block, done at L4 transverse process level in saggital orientation.
- Trial name
- NCT03733769
- Testing
- transmuscular quadratus lumborum block
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hip Osteoarthritis, Muscle Weakness
The Role of Surgical Approach on Residual Limping After Total Hip Arthroplasty
Residual limping after total hip arthroplasty is empirically associated with the use of lateral approach but has been reported in litterature even with the use of posterior approach.
- Conditions
- Hip Osteoarthritis, Muscle Weakness, Muscle Atrophy, Muscle Injury
- Trial name
- HSS (NCT05216666)
- Testing
- Lateral approach, Posterior approach
- Where
- Sweden
- Volunteers
- 580 people
- Sponsor
- Sahlgrenska University Hospital
Thyroidectomy, Thyroid Diseases
BABA Robotic Thyroidectomy Without Gas is Safe Enough as That Use a Gas
In this study, a randomized controlled study was conducted between two groups of 14 classic recipients of Carbon dioxide insufflation during BABA robotic-thyroidectomy and 14 recipients of Gasless method during BABA…
- Trial name
- NCT03922282
- Testing
- Gasless BABA, Classic BABA
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Inje University
Medulloblastoma
Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
Participants enrolling on this study will receive standard of care chemotherapy for Wnt positive medulloblastoma without the radiation therapy or the weekly chemotherapy that is given during radiation therapy.
- Trial name
- NCT02212574
- Testing
- Lomustine, Vincristine, Cisplatin
- Where
- 16 sites in United States
- Volunteers
- 6 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins