Clinical trials: Surgical Errors, open to volunteers
Myopic Traction Maculopathy
Predictors of Vitrectomy Outcomes in Myopic Foveoschisis
This prospective pilot study evaluates factors that predict outcomes after vitrectomy for myopic foveoschisis (MFS), a sight-threatening complication of high myopia that can lead to progressive visual loss, foveal detachment…
- Trial name
- NCT07774637
- Testing
- pars plana vitrectomy
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Cataract Surgery
Reducing Patient Waiting Time for Cataract Surgery
The purpose of this study is to examine how coordination between hospital departments affects patient flow between the free ward (B1), paid ward (C1) and the operating theatre (OT) for cataract surgeries at a tertiary eye care…
- Trial name
- NCT07484659
- Testing
- Standard Operating Procedures (SOPs)
- Where
- India
- Volunteers
- 360 people
- Sponsor
- Seva Canada Society
Myopia, Astigmatism
SMILE Surgery in One Eye Compared to Ray Tracing-guided LASIK Surgery in the Fellow Eye
Participants will undergo LASIK surgery in one eye using ray tracing guided technology in one eye and LASIK surgery in the other eye using wavefront guided technology.
- Trial name
- NCT07721714
- Testing
- Ray tracing guided LASIK surgery
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Stanford University
Myopia, High Myopia
Clinical Results of Small Incision Lenticule Extraction (SMILE) for the Correction of High Myopia
Small Incision Lenticule Extraction (SMILE) was introduced in 2011 using the VISUMAX femtosecond laser (Carl Zeiss Meditec, Jena, Germany). It is designed for correction of myopia and myopic astigmatism.
- Trial name
- NCT04110067
- Testing
- Small Incision Lenticule Extraction (SMILE) with Visumax (Carl Zeiss Meditec, Jena)
- Where
- Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Suphi Taneri
Postoperative Complication, Recovery, Physiological
Assessment of the Impact of Intestinal Gas Emission Quality on the Postoperative Course After Abdominal Surgery
The recovery of transit after surgery is an important parameter in postoperative evaluation. It generally reflects simple postoperative outcomes and allows the patient to return home.
- Trial name
- FLATQUAL (NCT06675097)
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Myopia, Astigmatism
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
This purpose of this study is to compare a new form of LASIK called Ray Tracing Guided LASIK to 3 other forms of corneal refractive surgery: 1. KLEx (KeratoLenticule Extraction) using the Zeiss Visumax 800 Laser, 2.
- Trial name
- NCT07201298
- Testing
- Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Refractive Surgery, Myopia; Refractive Error
Clinical Study of SMILE 4.0-VISULYZE in Correcting Refractive Errors
The aim of this study is to further optimize the surgical input parameters for patients undergoing Small Incision Lenticule Extraction (SMILE) using the regression model established by the SMILE 4.0-VISULYZE system, thereby…
- Trial name
- NCT06982807
- Testing
- Group 4.0-VISULYZE, traditional group
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Affiliated Hospital of Nantong University
Optical Coherence Tomography, Refractive Errors
To Study the Effects of Refractive Surgery on OCT Measurements in the Eye
Corrective eye surgeries, such as Lasik, are widely used to correct focusing problems such as myopia, or nearsightedness. Often these patients develop other conditions like myopic maculopathy or glaucoma which require monitoring…
- Conditions
- Optical Coherence Tomography, Refractive Errors, Myopia
- Trial name
- NCT05856786
- Testing
- Optical coherence tomography
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Nebraska
Irregular Astigmatism, Astigmatism
Improving Visual Quality in Patients With Irregular Corneas Using Asymmetrical Toric Intraocular Lenses
Cataract surgery in patients with irregular corneas presents unique challenges, primarily due to the high variability in keratometry and corneal tomography measurements, which complicates accurate intraocular lens (IOL)…
- Conditions
- Irregular Astigmatism, Astigmatism, Cataract and IOL Surgery
- Trial name
- VITAL (NCT07294716)
- Testing
- AMILens Individual
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Johannes Kepler University of Linz
Myopic Astigmatism
A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic Astigmatism
This will be a multicenter, prospective, open label, non-randomized, single arm study evaluating the safety and effectiveness of the Technolas® TENEO 317 Model 2 (version 1.28 US software) Excimer Laser when used in LASIK surgery…
- Trial name
- NCT07377474
- Testing
- TENEO 317 Model 2 (1.28 US) Excimer Laser
- Volunteers
- 32 people
- Sponsor
- Bausch & Lomb Incorporated
Corneal Astigmatism, Cataract
Effectiveness, Stability and Influence Factors of Femtosecond Laser Assisted Cataract Surgery
What is this study about? This study looks at whether a laser procedure called femtosecond laser-assisted arcuate keratotomy (FSAK) helps people with both cataracts and mild astigmatism see more clearly after cataract surgery.
- Trial name
- NCT07081919
- Testing
- femtosecond laser-assisted arcuate keratotomy (FSAK) combined with standard cataract surgery
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Stress Urinary Incontinence (SUI)
Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape
This prospective clinical study aims to compare the short-term effectiveness, safety, and patient-reported outcomes of two surgical techniques used for the treatment of female stress urinary incontinence (SUI): Pubo-Urethral…
- Trial name
- PLP-TOT (NCT07290114)
- Testing
- Pubo-Urethral Ligament Plication (PLP), Transobturator Tape (TOT)
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Mehmet Incebıyik
Non-Invasive Blood Pressure Monitoring During Thoracoscopic Surgery With One-Lung Ventilation
Blood Pressure Monitoring Accuracy in Patients Undergoing Lung Surgery With One-Lung Ventilation Using an Arm Cuff and Arterial Line
This study will test how accurate a blood pressure cuff is during a specific type of chest surgery. In some lung surgeries, doctors use a method called video-assisted thoracoscopic surgery (VATS), where small tools and a camera…
- Trial name
- NCT07107698
- Volunteers
- 90 people
- Sponsor
- Koç University
Presbyopia, Refractive Error
Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical Study
The goal of this clinical trial is to learn if laser blended vision (LBV) works better than traditional monovision LASIK to correct presbyopia in adults aged 40 to 55 years.
- Trial name
- NCT07512089
- Testing
- Laser Blended Vision LASIK, Traditional Monovision LASIK
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Pediatric Cataract, IOL Implantation
Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery
Myopic shift remains a debilitating and unpredictable adverse event following pediatric cataract surgery. While research exploring peripheral myopic defocus for post-cataract surgery myopia prevention shows promising results, the…
- Conditions
- Pediatric Cataract, IOL Implantation, Myopia Progression
- Trial name
- NCT07364370
- Testing
- Atropine Eye drops
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Myopia
Comparison of Myopic Small Incision Lenticule Extraction (SMILE) With VISUMAX 500 Versus VISUMAX 800 Platforms
Small incision lenticule extraction (SMILE) procedure is a well-known procedure for the correction of myopia. The purpose of this research study is to compare the two SMILE procedures with different laser platforms (VISUMAX 500…
- Trial name
- NCT07505264
- Testing
- SMILE surgery with Visumax 500, SMILE surgery with Visumax 800
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- Singapore Eye Research Institute
Colorectal Carcinoma (CRC), Right Hemicolectomy
The Intraoperative Technical Errors of Robotic vs. Laparoscopic Radical Right Hemiclectomy
Experimental design: This study is a multicenter, prospective, randomized, controlled phase III clinical trial that identifies, classifies, defines, and quantitatively analyzes technical errors between robotic and laparoscopic…
- Trial name
- NCT07138859
- Testing
- Robot assisted radical right hemicolectomy (D3 lymph node dissection), Laparoscopic assisted radical right hemicolectomy (D3 lymph node dissection)
- Where
- China
- Volunteers
- 368 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Nearsightedness, Farsightedness
An Evaluation of LASIK, SMILE and PRK Surgery in Physicians
The principle investigator is evaluating self-reported quality of vision and quality of life in physicians undergoing LASIK, SMILE and PRK surgery.
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT02576483
- Testing
- Questionnaire (QoV questionnaire)
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Stanford University
Esophageal Cancer
Outside the Cage (OTC) Robotic Esophagectomy
The goal of this clinical trial is to evaluate the feasibility and safety of a novel non-intercostal robotic approach for minimally invasive esophagectomy (OTC MIE) in the treatment of esophageal cancer.
- Trial name
- NCT06735638
- Testing
- OTC MIE Esophagectomy
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Adrenomyeloneuropathy Without Cerebral Involvement
Epidural Spinal Cord Stimulation for Lower-limb Impairment in Adrenomyeloneuropathy
Adrenal spinal neuropathy (AMN) is a rare X-linked genetic disease caused by mutations in the ABCD1 gene, and belongs to a special type of adrenal leukodystrophy.
- Trial name
- EPIC-AMN (NCT06796920)
- Testing
- Spinal cord stimulation
- Where
- 4 sites in China
- Volunteers
- 10 people
- Sponsor
- Third Military Medical University