Clinical trials: Surgical Incision
C.Delivery; Surgery (Previous), Gynecological
Incision Pain and Uterine Contraction Pain After Cesarean Section
This study aims to compare the pain degree between primary cesarean section and repeated cesarean section, and investigate the role of flurbiprofen axetil in postoperative analgesia, so as to provide reference for clinical…
- Trial name
- NCT02595333
- Testing
- Group SF1, Group S1, Group SF2
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fudan University
Surgical Wound, Surgical Wound Infection
Caesarean Wound Dressing Removal Study
An open labelled randomised trial on the timing of wound dressing removal for emergency caesarean delivery in labour.
- Conditions
- Surgical Wound, Surgical Wound Infection, Cesarean Section Complications
- Trial name
- Cesarean (NCT05458518)
- Testing
- Cesarean wound dressing removal
- Where
- Malaysia
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Hospital Kemaman
Wound Surgical, Diabetes
Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty
This study is a single-center, prospective, randomized, open-label clinical trial evaluating three commercially available closed-incision negative pressure wound therapy (ciNPWT) devices: NPseal, PICO, and Prevena, in adult…
- Conditions
- Wound Surgical, Diabetes, Obesity, Chronic Kidney Diseases
- Trial name
- NCT07770633
- Testing
- NP Seal, PICO, Prevena
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Clinical and Radiographic Effect, Thick-gingiva
Radiographic Evaluation of a Star-shaped Incision Technique
To evaluate a star-shaped incision technique to thick-gingiva and thingingiva patients treated with implant-supported fixed prosthesis.
- Conditions
- Clinical and Radiographic Effect, Thick-gingiva, Thin-gingiva, Implant
- Trial name
- NCT05190614
- Testing
- The biotype of gingiva
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wen Luo
Surgical Site Infection
Perioperative Patient Skin Antiseptic Preparation Evaluation
This study will evaluate a new topical skin antiseptic perioperative preparation and the standard of care to determine efficacy on the rates of surgical site infections of surgical patients. Safety will also be assessed.
- Trial name
- NCT04756804
- Testing
- 70% v/v Isopropyl Alcohol Surgical Solution, 2%w/v Chlorhexidine Gluconate / 70% v/v Isopropyl Alcohol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Myopia, Small-incision Lenticule Extraction (SMILE) Surgery
Potential Risk Factors and Predictive Model Construction of OBL During SMILE
To explore the prediction of OBL by deep learning model in SMILE surgery
- Trial name
- NCT06577012
- Testing
- Small incision lenticule extraction
- Where
- China
- Volunteers
- 4,678 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Myopia
Comparison of Femto LDV Z8 Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) and Visumax Small Incision Lenticule Extraction (SMILE)
This observational study aims to compare two laser corrective procedures for treating myopia and myopic astigmatism: a novel refractive technique, the CLEAR procedure, and the established SMILE procedure.
- Trial name
- NCT06774651
- Testing
- Procedure: Corneal lenticule extraction for advanced refractive correction (CLEAR), Procedure: Small Incision Lenticule Extraction (SMILE)
- Where
- Singapore
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Singapore Eye Research Institute
Surgical Site Infections
The Skin Prep Study
The investigators propose a randomized controlled clinical trial to determine the comparative effectiveness of chlorhexidine-alcohol and iodine-alcohol preoperative skin preparation for preventing surgical site infections at…
- Trial name
- NCT01472549
- Testing
- Iodine-alcohol, Chlorhexidine-alcohol
- Where
- United States
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stress Incontinence, Female
Single-incision Sling vs Urethral Bulking During Prolapse Surgery for Occult Stress Incontinence
The aim is to compare outcomes of two different procedures to prevent occult stress urinary incontinence (SUI) in patients who are having pelvic organ prolapse surgeries
- Trial name
- NCT05210738
- Testing
- Single incision sling, Bulkamid bulking agent
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Christ Hospital
Wound Heal, Wound Surgical
Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III
The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues.
- Conditions
- Wound Heal, Wound Surgical, Oral Soft Tissue Conditions, Hyaluronic Acid
- Trial name
- NCT04865952
- Testing
- periodontal surgery + 24 hr buccal attached gingiva (G) biopsy, HA application
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Mitochondrial Oxygenation Measurement, Surgical Site Infection
Anaesthetic Management Guided by COMET Measurements
Surgical site infection (SSI) is a significant cause of morbidity and mortality, prolonged hospital stays and healthcare costs. Perioperative low tissue oxygen tension is associated with a high risk of SSI.
- Trial name
- AIMED COMET (NCT05841576)
- Testing
- COMET monitoring device
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Rick Hulskes
Surgical Wound
Blood Characteristics and Abdominal Emergency Surgery
After surgical tissue damage, cellular blood components are involved in tissue repair processes, yet their preoperative characteristics are not considered in routine clinical practice.
- Trial name
- NCT06028854
- Where
- 2 sites in Chile
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chile
Pain, Postoperative
Pre-incision Versus Post-incision Local Anesthetic During Robotic Sacrocolpopexy
Obtaining Likest-pain scale score on postoperative day one after injection of local anesthetic into incision sites of a laparoscopic/robotic-assisted sacrocolpopexy
- Trial name
- CLAPPS (NCT04996251)
- Testing
- Bupivacaine Injection
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Dental Implant Failed
Evaluation of Esthetic Outcomes of M-shaped Flap Implant Uncovering Technique Versus I-shaped Incision Around Single Implants in the Anterior Maxilla Using Pink Esthetic Score
The aim of this study is to evaluate the soft-tissue profile around a single-tooth implant in the anterior maxilla utilizing the PES after implant uncovering using "M" flap versus I-shaped incision.The primary objective is…
- Trial name
- NCT04102748
- Testing
- I-incision, M-flap and conventional implant exposure techniques
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wound Dehiscence
Flipped Autograft for Treating Surgical Wound Dehiscence
This case report describes a novel technique for management of peri-implant wound dehiscence that involves using auto graft from the same surgical site to seal the dehiscence defect.
- Trial name
- NCT05513222
- Testing
- flipped autograft
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Laparoscopic Surgical Procedures
Comparison of Single İncision Laparoscopic Cholecystectomy Versus Laparoscopic Cholecystectomy
The aim of this study is to compare outcomes of quality-of-life measures and evaluate the body image and cosmesis between Single Incision Laparoscopic Cholecystectomy (SILC) and Conventional Laparoscopic Cholecystectomy…
- Trial name
- NCT02417857
- Testing
- Laparoscopic Cholecystectomy (Single Incision), Laparoscopic Cholecystectomy (Conventional)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ankara Mevki Military Hospital
Hyperopia
Clinical Trial of the Femtosecond Laser System VisuMax for Refractive Correction of Hyperopia by Means of Lenticule Extraction
This is a feasibility and clinical evaluation study of the VisuMax femtosecond laser for refractive correction of hyperopia using the small incision lenticule extraction (ReLEx smile) method.
- Trial name
- NCT02316041
- Testing
- Small incision lenticule extraction, ReLEx® (SMILE)
- Where
- Nepal
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Tilganga Institute of Ophthalmology
Flap Advancement
Comparison of Double-Flap Incision, Modified Periosteal Releasing Incision, and Coronally Advanced Lingual Flap to Periosteal Releasing Incision for Flap Advancement
Guided Bone Regeneration (GBR) is a reliable method to augment insufficient bone volume for implant placement. Membrane exposure is a major complication which is avoided by tension free primary closure.
- Trial name
- NCT03787342
- Testing
- Double Flap Incision, Modified Periosteal Releasing Incision, Coronally Advanced Lingual Flap
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University