Clinical trials: Surgical Positioning
Rectal Cancer, Abdominoperineal Resection
Abdominoperineal Extra-Elevators Rectal Resection for Cancer: Prone Position vs. Supine Position
Prospective multicenter randomized controlled trial comparing the prone vs. the supine position of the perineal time of the Miles operation in patients with advanced rectal cancer.
- Trial name
- APPRO (NCT02163785)
- Testing
- Abdominoperineal extra-elevators rectal resection for low lying rectal cancer
- Where
- 19 sites in Spain
- Volunteers
- 280 people
- Sponsor
- Hospital Universitario La Fe
Knee Arthritis
Comparison of Implant Positioning With Robotic Aided Surgery and Traditional Jig Positioning in Total Knee Arthroplasty
The purpose of this study is to compare the outcomes and accuracy of implant positioning in robotic assisted total knee arthroplasty with traditional manually instrumented total knee arthroplasty.
- Trial name
- NCT03052790
- Testing
- manually instrumented total knee arthroplasty, robotic assisted total knee arthroplasty
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Shouldersurgery
Assessing Cerebral Blood Flow Autoregulation During Surgery in the Head-up Position
Neurological injury after elective shoulder surgery in the beach chair position is thought to result from cerebral hypoperfusion and should therefore be preventable by appropriate hemodynamic monitoring and management.
- Trial name
- NCT01225185
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Johns Hopkins University
Pressure Ulcer
Effectiveness of Sacral Foam Pad in Preventing Pressure Injury in Surgical Patients With Supine Position
In surgical patients, prevention of pressure injury is a challenge because of the high risk for multiple comorbid conditions, hemodynamic instability, and long duration of immobility.
- Trial name
- NCT03557489
- Testing
- Mepilex Border Sacrum
- Volunteers
- 210 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Cerebral Hypoxia During and/or Resulting From A Procedure
The Effects of Body Mass İndex On İntraabdominal Pressure And Regional Cerebral Oxygen Saturation İn Prone Position
A total of 40 ASA (American Society of Anesthesiology) physical status I-III who underwent lumbar disc hernia repair for one or two levels were included in this prospective study.
- Trial name
- NCT05392478
- Volunteers
- 40 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Atelectasis, Mechanical Ventilation
Effects of Periodic Recruitment Maneuvers on Atelectasis and Respiratory Mechanics During Elective Spine Surgery Assessed by Lung Ultrasonography
During general anesthesia, particularly in patients undergoing spine surgery in the prone (face-down) position, increased intrathoracic and abdominal pressure may reduce lung compliance and promote the development of atelectasis…
- Conditions
- Atelectasis, Mechanical Ventilation, General Anesthesia, Prone Position
- Trial name
- NCT07325812
- Testing
- Alveolar Recruitment Maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Mechanical Ventilation, General Anesthesia
Comparison of Volume-controlled and Pressure-controlled Ventilation in Clasp-knife Position
Carbon dioxide (CO2) pneumoperitoneum and clasp-knife positioning are commonly used to improve surgical access during robot-assisted laparoscopic urological surgery.
- Conditions
- Mechanical Ventilation, General Anesthesia, Urological Surgery, Robotic Surgery
- Trial name
- NCT06056401
- Testing
- record Hemodynamic variables, respiratory variables and arterial blood gas at specific times
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University
Pulmonary Atelectasis
Descriptive and Comparative Study of Respiratory Function in the Postoperative Cardiac Surgery Patient
The study comprises two different objectives. Longitudinal description of postoperative pulmonary dysfunction in the cardiothoracic surgery patient, and the comparison of two different lungrecruitment strategies.
- Trial name
- NCT03009331
- Testing
- Lungrecruitment manoeuver in prone position., Lungrecruitment manoeuver in supine position.
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Estrogen Receptor-positive Breast Cancer, Invasive Ductal Breast Carcinoma
Intensity Modulated Accelerated Partial Breast Irradiation Before Surgery in Treating Older Patients With Hormone Responsive Stage 0-I Breast Cancer
This pilot clinical trial studies intensity-modulated accelerated partial breast irradiation (APBI) before surgery in treating older patients with estrogen receptor positive or progesterone receptor positive stage I breast…
- Conditions
- Estrogen Receptor-positive Breast Cancer, Invasive Ductal Breast Carcinoma, Invasive Ductal Breast Carcinoma With Predominant Intraductal Component, Medullary Ductal Breast Carcinoma With Lymphocytic Infiltrate
- Trial name
- NCT02186470
- Testing
- accelerated partial breast irradiation, intensity-modulated radiation therapy, image-guided radiation therapy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Zygomaticomaxillary Complex Fracture, Zygoma Fracture
Accuracy of Positioning Guide and Customized Plate in Zygomaticomaxillary Complex Fractures
The goal of this clinical trial is to evaluate the accuracy and stability of positioning guides and customized titanium plates in the treatment of Zygomaticomaxillary Complex (ZMC) fractures.
- Conditions
- Zygomaticomaxillary Complex Fracture, Zygoma Fracture, Zygomatic Fractures
- Trial name
- NCT07608380
- Testing
- Patient-specific positioning guide, Customized titanium plate
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Intra-operative Bleeding
Can Head Position Improve Surgical Field During Ear Surgery?
Middle ear surgeries utilizes microscope in a narrow field. They are better performed under controlled hypotension, to minimize bleeding and improve surgical field visualization and hence improve results.Head-up or…
- Trial name
- NCT04095754
- Testing
- Head-Up Position, Dexmedetomidine, Induction and maintenance of anaesthesia
- Where
- 2 sites in Egypt
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Intraocular Pressure
Effects of Dexmedetomidine on Intraocular Pressure During Scheduled Spine Surgeries
The aim of this study is to examine the effects of intraoperative systemic use of dexmedetomidine on the intraocular pressure (IOP) in patients undergoing spine surgeries in a prone position under general anesthesia.
- Trial name
- NCT04628663
- Testing
- Dexmedetomidine, Normal Saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
CAD-CAM, Patients Specific Manufacturing
Analysis of Mandibular Proximal Segment Position Using Virtual Orthognathic Surgical Planning, Individualized Guides, and Osteosynthesis Plates
Orthognathic surgery is a surgical procedure performed to correct dentofacial deformities. In recent years, with the use of virtual surgical planning, cutting guides, and patient-specific osteosynthesis plates, highly predictable…
- Conditions
- CAD-CAM, Patients Specific Manufacturing, Osteotomy, Sagittal Split Ramus
- Trial name
- NCT06442787
- Testing
- conventional splints, cutting guides and positioning guides, cutting guides and fixation plates
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Robotic Surgical Procedures
Prevention of Endotracheal Tube Migration by Cuff Palpation During Robotic Surgical Procedure
After intubation, the endotracheal tube was finally fixed after palpating endotracheal cuff at three sites (just below the cricoid cartilage, at suprasternal level and just below suprasternal notch).
- Trial name
- NCT04440787
- Testing
- Three point cuff palpation technique
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Spine Fusion, Spinal Stenosis
Single Position Spine Surgery Registry
The purpose of this study is to systematically, prospectively compare surgical fusion techniques for thoracolumbar spinal fusion patients and assess long-term patient outcomes and revision rates following surgery.
- Conditions
- Spine Fusion, Spinal Stenosis, Degenerative Disc Disease
- Trial name
- SPSG Registry (NCT04839783)
- Where
- 6 sites in United States, Australia
- Volunteers
- 234 people
- Sponsor
- Spine and Scoliosis Research Associates
Hemodynamic Variation During Surgery
Mean Systemic Pressure Measurement During Prone Position Surgery
Venous return is driven by the pressure gradient between mean systemic pressure and right atrial pressure. However, mean systemic pressure is more a physiological concept than an available clinical measurement.
- Trial name
- NCT01957605
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Lumbar Stabilization Surgery, Noninvasive Hemoglobin Monitoring
Effect of Prone Position on Continuous Noninvasive Hemoglobin Measurement
This prospective observational study aims to evaluate whether the prone position affects the agreement between noninvasive hemoglobin (SpHb) measurements and laboratory hemoglobin values in patients undergoing lumbar…
- Trial name
- NCT07823569
- Testing
- Prone Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Trendelenburg Position, Pneumoperitoneum
Predictors of Postoperative Complications in Surgery With Pneumoperitoneum in the Trendelenburg Position
Evaluate early postoperative complications after surgery in Trendelenburg position with increased intraabdominal pressure (surgery with pneumoperitoneum).
- Trial name
- NCT06685159
- Testing
- Laparoscopic Surgery
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Reuven Pizov
Spinal Diseases, Local Anesthesia
The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia
Evaluate safety and efficacy of dexmedetomidine in minimally invasive spine surgery under local anesthesia sedation.Explore the appropriate concentration of dexmedetomidine, whether or not can reduce the amount of local…
- Trial name
- NCT02535273
- Testing
- Dexmedetomidine, Lidocaine, Low-dose Dexmedetomidine
- Volunteers
- 212 people
- Sponsor
- Tang-Du Hospital
Craniotomy Surgery, Pediatric Patient Safety
The Effect Of Positive End-Expiratory Pressure on Optic Nerve Sheath Diameter In Pediatric Patients Undergoing Craniotomy in Supine Position
This study evaluated the effect of positive end-expiratory pressure (PEEP) on optic nerve sheath diameter (ONSD), an indicator of intracranial pressure, in pediatric patients undergoing craniotomy in the supine position.
- Conditions
- Craniotomy Surgery, Pediatric Patient Safety, Pediatric Patient, Positive End-expiratory Pressure (PEEP)
- Trial name
- NCT07370779
- Testing
- General Anesthesia, Anesthetic Agents, mechanical ventilation (MV)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital