Clinical trials: Surgical Procedures, Elective
Elderly Patients Undergoing Elective Non-cardiac Surgery
Ultrasound of the Inferior Vena Cava in the Prevention of Hypotension After Induction of General Anesthesia
Based on the preoperative ultrasound detection of various parametric indicators of the inferior vena cava cross-section, including the ratio of the inferior vena cava's long and short axes, cross-sectional area and circumference…
- Trial name
- NCT06530901
- Testing
- Multidimensional ultrasound of the inferior vena cava
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhuan Zhang
Ovarian Cancer
Influences of Propofol and Sevoflurane Anesthesia in Ovarian Cancer (Anesthetics)
Ⅶ. Study procedures (summary) 1. Written informed consent must be obtained before any study specific procedures are undertaken. Qualified participants were identified at the pre-anesthesia evaluation clinic or ward.
- Trial name
- anesthetics (NCT05606692)
- Testing
- Propofol 1%, Sevoflurane/Ultane
- Where
- Taiwan
- Volunteers
- 416 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Venous Thromboembolism
A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants
This study is researching an experimental drug called REGN7508 (called "study drug"). The study is focused on adults undergoing elective, unilateral (one side) total knee replacement (TKR) surgery.
- Trial name
- ROXI-VTE II (NCT06454630)
- Testing
- REGN7508, Enoxaparin
- Where
- 14 sites in Bulgaria, Hungary and 3 more
- Volunteers
- 179 people
- Sponsor
- Regeneron Pharmaceuticals
Frailty in Adult Surgery, Frailty Syndrome
Validity of Frailty Screening Tools as a Measure for Postoperative Outcomes
Frailty is a common geriatric syndrome defined as a clinical state of decreased physiologic reserve resulting in increased vulnerability to stressors.
- Conditions
- Frailty in Adult Surgery, Frailty Syndrome, Elective Surgery
- Trial name
- NCT07367828
- Testing
- Intermediate/major elective surgery
- Where
- Iceland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Peer Review, Research
Scheduled Elective Surgical Case Cancellation in Siriraj: Evaluation and Identification of the Reasons
A retrospective cross-sectional analytic study to evaluation and identification of the reasons about Scheduled elective surgical case cancellation in Siriraj Hospital, reason of cancellation will be extracted from hospital…
- Trial name
- NCT02816281
- Where
- Thailand
- Volunteers
- 2,760 people
- Sponsor
- Siriraj Hospital
Atrial Fibrillation
Perioperative Anticoagulant Use for Surgery Evaluation Study
The aim of the Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study, is to establish a safe, standardized protocol for the perioperative management of patients with atrial fibrillation (AF) who are receiving a…
- Trial name
- PAUSE (NCT02228798)
- Where
- 21 sites in United States, Belgium and 3 more
- Volunteers
- 3,135 people
- Sponsor
- McMaster University
Post Operative Cognitive Dysfunction
Post-Operative Cognitive Dysfunction in Normal Aging Patients Undergoing Elective Orthopedic Surgery
Post-operative cognitive dysfunction (POCD) is a common concern for aging patients undergoing elective orthopedic surgery and significantly effects health outcomes.
- Trial name
- POCD (NCT04267328)
- Testing
- Elective Orthopedic Surgery
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- HealthPartners Institute
Postoperative Recovery, Anesthesia, General
Quality of Recovery-15 After Opioid-free Versus Opioid-based General Anesthesia in Major Urological Surgery
This randomized controlled trial evaluates postoperative quality of recovery assessed with the Quality of Recovery-15 questionnaire in adult patients undergoing elective major urological surgery under opioid-free versus…
- Conditions
- Postoperative Recovery, Anesthesia, General, Analgesics, Opioid, Urologic Surgical Procedure
- Trial name
- QoR-OFA-URO (NCT07665463)
- Testing
- Remifentanil-based general anesthesia, Opioid-free general anesthesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Nausea, Vomiting
Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries
The combination of aprepitant and lower dose dexamethasone is superior to aprepitant alone with respect to the proportion of patients with a complete response (no vomiting and no use of rescue therapy) during 24 hours after the…
- Trial name
- NCT00835965
- Testing
- Dexamethasone, Aprepitant
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Main Line Health
Elective Colorectal Surgery
Impact of Preoperative Single Corticosteroid Flash on Morbidity After Colorectal Resection: Monocentric Prospective Pilot Study
Complications due to infection after colorectal surgery are frequent, affecting up to 25% of patients. Infection increases mortality, lengthens hospital stays, increases costs and decreases long term survival for cancer patients.
- Trial name
- CORTICOLON (NCT03437746)
- Testing
- injection of methylprednisolone at anesthetic induction, Blood samples
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pregnancy
Elective Induction of Nulliparous Labor
Primary outcome: to evaluate the effect of elective induction of labor (IOL), at 39 weeks gestation, on cesarean delivery rates in nulliparous women compared to expectant management (EM).
- Trial name
- NCT01076062
- Testing
- Induction of Labor
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Coronary Artery Disease, Angina, Unstable
Study on Safety and Effectiveness of Three Doses of Argatroban as Anticoagulant in Percutaneous Coronary Intervention (PCI)
This is a phase II multi-centre study in 140 patients undergoing elective PCI to obtain the information on dose-response of argatroban in pharmacodynamic markers and to assess the anticoagulation, safety and efficacy of…
- Trial name
- NCT00508924
- Testing
- Argatroban, Heparin
- Where
- 8 sites in Belgium, Germany
- Volunteers
- 140 people
- Sponsor
- Tanabe Pharma Corporation
Coronary Artery Disease
Antithrombotic Regimens and Outcome
PROTOCOL SYNOPSIS Title: Comparison of bivalirudin and unfractioned heparin (UFH)+ protamine in elective percutaneous coronary interventions (PCI) Design: Prospective, randomized, controlled trial Hypothesis: Bivalirudin is…
- Trial name
- ARNO (NCT00448461)
- Testing
- heparin, bivalirudin
- Where
- Italy
- Volunteers
- 850 people
- Sponsor
- Careggi Hospital
Coronary Heart Disease
Safety and Efficacy of Prolonged Use of Bivalirudin 4 Hours After ePCI (COBER Study)
Since the development of percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD), unfractionated heparin (UFH) and low molecular weight heparin (LWMH) have been the preferred anticoagulants in…
- Trial name
- NCT04120961
- Testing
- prolonged continuous use of bivalirudin, bivalirudin use during ePCI
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Analgesia Disorder
Transverse Abdominal Block for Analgesia in Casarean Section
In this study, the investigators will compare the analgesic effect of bupivacaine and bupivacaine-dexmetomedine after elective cesarean delivery by performing an bilateral TAP block, on the patients for whom the operation will be…
- Trial name
- NCT02122510
- Testing
- Bupivacine group, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Thrombocytopenia
Treatment of Avatrombopag for Thrombocytopenia in Patients Undergoing Selective Resection of Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world, accounting for the second leading cause of cancer death in China.Surgical treatment of hepatocellular carcinoma is the most important means…
- Trial name
- NCT05087459
- Testing
- Avatrombopag
- Where
- China
- Volunteers
- 141 people
- Sponsor
- Shanghai Zhongshan Hospital
Surgery, Anesthesia Intubation Complication
MAsk VEntilation With Paratracheal Pressure In Children. Para Tracheal Compression to Prevent Gastric Insufflation in Children
The use of cricoid pressure to prevent gastric aspiration or regurgitation in case of "full stomach" situation or emergency is still controversial in the adult population.
- Trial name
- MAVEPPIC (NCT05279170)
- Testing
- MAVEPPIC: MAsk VEntilation with Paratracheal Pressure In Children
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Lille
Neurosurgery, Elective Craniotomy
Neuro-Ox 2018: Assessment of Cerebral Oxygenation Under Three Clinically Relevant Conditions
This is a prospective observational study, consisting of 3 substudies carried out during elective neurosurgery under general anaesthesia. Each participant will take part in all 3 substudies.
- Conditions
- Neurosurgery, Elective Craniotomy, General Anaesthesia
- Trial name
- NCT03682198
- Testing
- NIRS measurements on skin, skull and dura, Phenylephrine's effect on brain oxygenation, Normal vs. high inspired oxygen
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Cesarean Section Complications
Mechanical Dilatation of the Cervix at Elective Caesarean Section on Post-operative Morbidity
The study aims to evaluate the effects of cervical dilatation during cesarean section on postoperative maternal morbidity through different clinical parameters.
- Trial name
- NCT05997498
- Testing
- mechanical cervical dilatation
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Beni-Suef University
Colonoscopy
Transcutaneous Measurement of Carbon Dioxide Versus Current Sedation Practices in Sedated Patients
Does transcutaneous carbon dioxide partial pressure (TcCO2) monitoring detect hypoventilation prior to current sedation monitoring practices in order to prevent hypoxemia in sedated patients undergoing colonoscopies?
- Trial name
- NCT01060709
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- University Medical Center Groningen
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