Clinical trials: Surgical Procedures, Operative
Sars-CoV2
Incidence of COVID-19 Test Conversion in Post-surgical Patients
The current Sars-CoV-2 (COVID-19) pandemic has created major changes in how physicians perform routine healthcare for our patients, including elective and non-elective surgical procedures.
- Trial name
- NCT04392323
- Testing
- COVID-19 PCR and Serology
- Where
- 2 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Gingivitis and Periodontal Diseases
Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in Gingivitis
Gingivitis is an early and reversible form of periodontal disease characterized by an increased inflammatory response to dental biofilm.
- Trial name
- NCT07882394
- Testing
- Alpha-Lipoic Acid 200 mg, Alpha-Lipoic Acid 600 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Saliva, Cortisol
Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey
Periodontitis is a multifactorial, chronic inflammatory disease caused by many factors such as pathogenic microorganisms, host response, environmental and systemic factors.
- Conditions
- Saliva, Cortisol, Smoking, Tobacco, Periodontal Bone Loss
- Trial name
- NCT06809439
- Testing
- Non-Surgical Intervention, Saliva Collection (Baseline), Probing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Chronic Periodontitis
Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers
The study proposes to assess the effect of multiple applications of antimicrobial Photodynamic Therapy (aPDT) as an adjunct to non-surgical periodontal treatment (nsPT) in smokers without use of antibiotics.
- Trial name
- NCT03039244
- Testing
- Photodynamic therapy, Control Group, Diode Laser
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Surgical Glove, Total Knee Arthroplasty
Comparison of Surgical Glove Contamination During Total Knee Arthroplasty Procedure : a Randomized Controlled Trial
Total knee arthroplasty post-op surgical site infection rate about 0.5- 5% Pre-operative , perioperative and post-operative prevention are importance for reduce surgical site infection The prevention of surgical-site infections…
- Conditions
- Surgical Glove, Total Knee Arthroplasty, Contamination Rate
- Trial name
- NCT04308798
- Testing
- Surgical glove changing
- Where
- Thailand
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Education, Medical
Perceptions of the Annual Review of Competence Progression (ARCP) in Surgical Training in the UK and Ireland
A Prospective Cross Sectional Questionnaire Study was conducted to evaluate surgical trainees' experiences of the ARCP process in order to identify areas for improvement.
- Trial name
- NCT03718481
- Testing
- ARCP Process
- Where
- United Kingdom
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University College Hospital Galway
Surgical Skin Preparation
Clinical Evaluation of Patient Preoperative Prep
The objective of the study is to demonstrate the antimicrobial efficacy of the ZP Preoperative Prep on skin flora of the abdomen and inguinal regions of human subjects.
- Trial name
- NCT02831816
- Testing
- ZuraPrep, ChloraPrep, ZP Vehicle
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Alveolar Cleft
Evaluation of Autogenous Tooth- Derived Graft With Bovine Bone For Surgical Repair of Unilateral Alveolar Cleft
The aim of this study is evaluation of autogenous tooth-derived graft combined with bovine bone for surgical repair of unilateral alveolar cleft .
- Trial name
- NCT06855875
- Testing
- autogenous tooth graft combined with bovine bone, bovine bone
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanta University
Stable Angina Pectoris, Periodontitis
Effect of Periodontal Therapy on Asprosin in Stable Angina
This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis.
- Trial name
- NCT07591844
- Testing
- Non-surgical periodontal therapy (scaling and root planing), Non-surgical periodontal therapy (Professional dental cleaning)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Proliferative Diabetic Retinopathy
Intravitreal Bevacizumab for Surgical Treatment of Severe Proliferative Diabetic Retinopathy
The purpose of this study is to evaluate the role, the safety and the effectiveness of Intravitreal Bevacizumab injections as an adjunct to vitrectomy in the management of severe proliferative diabetic retinopathy.
- Trial name
- NCT01025934
- Testing
- Bevacizumab
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Periodontitis
A Closed Surgical Technique vs Papilla Preservation Techniques
A pioneer periodontal surgical approach employing the closed surgical technique (CST) has been designed to gain access to isolated interdental periodontal defects and retain the soft-tissue architecture.
- Trial name
- CST (NCT05754307)
- Testing
- Access Flap, Closed Surgical Technique
- Where
- Greece
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Danae A. Apatzidou
Residual Disease, Aggressive Periodontitis
Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis
The aim of this randomized controlled clinical trial of superiority will be to evaluate the effect of 3 g of omega-3 polyunsaturated fatty acids and 100 mg of aspirin daily supplementation over a period of 180 days as adjunct to…
- Trial name
- NCT03093207
- Testing
- Open flap debridement, Omega-3 polyunsaturated fatty acids, Aspirin
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Fistula in Ano
Management of Fistula in Ano by Kshar Sutra, Para Surgical Procedure.
Background: Fistula in ano is one of the most common diseases of the ano rectal region. Treatment of Fistula in ano has puzzled the medical fraternity due to its complex nature.
- Trial name
- Bhagandar (NCT01880398)
- Testing
- Kshar Sutra
- Where
- India
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Government Ayurved College and Hospital
Surgical Education
The Effect of Structured Feedback on Live Surgical Performance
This study seeks to establish the effect of regular structured feedback on surgical performance using crowd sourced video assessments with validated objective performance scores and time to complete a specific surgical procedure…
- Trial name
- CSATS (NCT02986217)
- Testing
- regular structured assessment of surgical performance
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- George Washington University
Postoperative Thromboembolism
Effect of Tumescent Lidocaine on Platelet Function
The purpose of this study is to evaluate the effect of lidocaine, delivered into subcutaneous tissue for tumescent local anesthesia, on platelet activation following the tumescent liposuction.
- Trial name
- NCT01463280
- Testing
- tumescent lidocaine infiltration
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.
Catheterization, Central Venous, Ultrasonography
To Compare the In-plane and Out of Plane Ultrasound Guided Approach for Internal Jugular Vein Cannulation in the Patients Undergoing Elective Cardiac Surgery.
The insertion of central venous catheters (CVCs) has become an integral part of management of a critically ill patient. Access to the central vein may be required for the administration of hyper osmotic or vasoactive compounds…
- Conditions
- Catheterization, Central Venous, Ultrasonography, Cardiac Surgical Procedures
- Trial name
- NCT04840810
- Testing
- In-plane Axis, Out of plane Axis
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Surgical Site Infection, Capsular Contracture Associated With Breast Implant
Postoperative Antibiotics Following Primary and Secondary Breast Augmentation
Postoperative antibiotics are routinely used for implant-based breast augmentation at the investigators' institution. From 2017-2019, the investigators' institution has conducted approximately 270 primary and secondary breast…
- Conditions
- Surgical Site Infection, Capsular Contracture Associated With Breast Implant, Antibiotic Resistant Infection, Antibiotic Side Effect
- Trial name
- NCT04834310
- Testing
- Cefazolin, Cephalexin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Surgical, Surgical Behaviour in the Operating Room
The Impact of Classical Music on Performance in Robotic Surgery Simulation
In this experimental crossover study using the da Vinci simulator, the aim is to investigate how classical music influences the surgical performance of medical students.
- Conditions
- Surgical, Surgical Behaviour in the Operating Room, Da Vinci Robot, da Vinci SP Surgical System
- Trial name
- NCT07639788
- Testing
- Exposure to Classical Music
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pain, Postoperative
A COMPARISON OF TRANSDERMAL DICLOFENAC AND ORAL COMBINATION OF PARACETAMOL AND IBUPROFEN IN POSTOPERATIVE PAIN MANAGEMENT FOLLOWING SURGICAL EXTRACTION OF MANDIBULAR THIRD MOLAR- A RANDOMISD CONTROLLED TRIALS.
This is comparative interventional study, will be conducted in patient indicated for surgical extraction of mandibular third molar at the Department of Oral and Maxillofacial surgery, College of Dental Surgery, BPKIHS, Nepal.
- Trial name
- NCT06146491
- Testing
- Oral tablet and transdermal patch
- Where
- Nepal
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Pain, Postoperative
Extraction of Distoangular and Vertically Positioned Mandibular 3rd Molars
Mandibular 3rd molars are the most commonly impacted teeth in oral cavity followed by maxillary 3rd molars and maxillary canines respectively.
- Trial name
- NCT05032989
- Testing
- Extraction of mandibular 3rd molar via Cowhorn forcep technique, Extraction of mandibular 3rd molar via conventional technique
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences