Clinical trials: Surgical Resection
Endometriosis
Feasibility and Potential Aids of Intra-operative Endo-vaginal Ultrasound When Performing Rectal Shaving for Endometriosis
The protocol of this study consists in the inclusion of patients with endometriosic rectal involvement with a scheduled intervention.
- Trial name
- ECHOENDO (NCT05499884)
- Testing
- Endovaginal ultrasound
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Lille
Rectal Cancer, Anastomotic Leak
Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing
LifeSeal™ Kit, surgical sealant designed for staple-line reinforcement that is applied over the anastomotic line to prevent bowel content leakage until full physiological function is restored.
- Trial name
- NCT02907385
- Testing
- LifeSeal™ Kit
- Where
- 39 sites in United States, Belgium and 5 more
- Volunteers
- 736 people
- Sponsor
- LifeBond Ltd.
Crohn Disease
Surgically Resected Crohn's Disease Patients: Prognostic Factors for Re-operation and New Score Building
The project will consist of a multicentre, prospective, observational study with a total duration of 24 months. Clinical, endoscopic and ultrasound data will be collected in a dedicated database (on IG-IBD Register), which will…
- Trial name
- POCD2017 (NCT03150238)
- Testing
- observation of prognostic factors for relapse
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Istituto Clinico Humanitas
Low Anterior Resection, Proctosigmoid Resection
Radial Reload Open LAR Case Series
The purpose of this research study is to evaluate the safety and feasibility of the Radial Reload Stapler during open LAR for rectal cancer. The surgeon will complete questionnaires relating to the function of the device.
- Conditions
- Low Anterior Resection, Proctosigmoid Resection, Rectal Cancer
- Trial name
- NCT01717014
- Testing
- Covidien Radial Reload Stapler with Tri-Staple Technology
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- Medtronic - MITG
Osteoarthritis
The Impact of Total Knee Arthroplasty Surgical Technique on Coronal Plane Motion and PatelloFemoral Articulation
The purpose of this study is to examine the impact of two surgical techniques on the outcome of the knee replacement surgery.
- Trial name
- NCT01855906
- Testing
- Gap balanced surgical technique, Measured resection
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Colorectal Cancer
Surgical Prehabilitation of Cancer Patients Undergoing Colorectal Resection.
Psychological distress is common among adults newly diagnosed with cancer and those awaiting cancer treatment(s). Although preoperative psychological distress has been shown to be associated with poorer physical health and…
- Trial name
- NCT04248647
- Testing
- Multimodal prehabilitation
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Neoplasm of Rectum, Surgery--Complications
Validation of Low Anterior Resection Syndrome Score in Korean Version
In contemporary era of rectal cancer treatment, development of surgical technique and tool, adaptation of chemoradiation therapy, as well as multidisciplinary approach have led increased survival as well as rate of sphincter…
- Conditions
- Neoplasm of Rectum, Surgery--Complications, Surgery
- Trial name
- NCT03211715
- Testing
- questionnaire
- Volunteers
- 300 people
- Sponsor
- Saint Vincent's Hospital, Korea
Rectal Cancer
Short Term Outcomes of Robotic-assisted Intersphincteric Resection for Low Rectal Cancer
This study compared robot-assisted total mesorectal excision to treat very low rectal cancer within 2 cm from the dentate line to avoid permanent colostomy.
- Trial name
- R-ISR (NCT03597126)
- Testing
- Robot-assisted surgery, Laparoscopic surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Southwest Hospital, China
Hepatocellular Carcinoma
Prospective, Multicenter HCCIS Evaluation Study
With this prospective, multicenter trial the investigators aim to establish the Hepatocellular Immune Score (HCCIS), a score that has been developed in a retrospective study, as a new tool for risk stratification of patients…
- Trial name
- HCCIS (NCT02718235)
- Testing
- Overall survival
- Volunteers
- 200 people
- Sponsor
- University of Regensburg
Endoscopic Mucosal Resection, Colonic Neoplasms
Efficacy and Safety of a Solution for Endoscopic Mucosal Resection of Colonic Lesions
The objetive of this clinical trial is to evaluate the efficacy and safety of a solution for endoscopic mucosal resection of colonic lesions in patients undergoing endoscopic resection procedures.
- Conditions
- Endoscopic Mucosal Resection, Colonic Neoplasms, Therapeutic Irrigation, Treatment Outcome
- Trial name
- NCT06910514
- Testing
- Mucopolysaccharide saline solution 0.9%, Saline solution 0.9%
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Nakafarma S.L.
Robotic Surgical Procedure, Thymoma
A Prospective, Single-Center Investigation of the da Vinci SP® Surgical System in Anterior Mediastinal Disease
Endpoints (Outcome measures)： 1. Primary endpoint: Incidence of conversion rate during surgery The primary performance endpoint will be assessed as the ability to successfully complete the planned mediastinal procedure with da…
- Conditions
- Robotic Surgical Procedure, Thymoma, Myasthenia Gravis
- Trial name
- NCT05455840
- Testing
- Da Vinci SP surgical platform
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Chang Gung Memorial Hospital
Drain
Effect of Ice Pack and Warm Gel Pad Use During Drain Removal on Anxiety, Comfort, Physiological Parameters, and Patient Satisfaction Undergoing Open Urological Surgery
The study was planned as a randomized controlled experimental study to determine the effects of ice pack and warm gel pad application during drain removal on anxiety, comfort, hemodynamic parameters, and patient satisfaction in…
- Trial name
- NCT07408921
- Testing
- Ice Pack, Warm Gel Pad Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Locally Advanced Rectal Cancer, Abdominoperineal Resection
Detection and Inflammatory Characterization of Deep Infection After Surgery for Locally Advanced Rectal Cancer With Microdialysis Catheters
The intention of the study is to explore metabolic and inflammatory parameters in the pelvis after abdominoperineal resection for locally advanced rectal cancer in patients that have received radiation therapy before surgery.
- Conditions
- Locally Advanced Rectal Cancer, Abdominoperineal Resection, Infection
- Trial name
- NCT03392584
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Rectal Cancer, Abdominoperineal Resection
Abdominoperineal Extra-Elevators Rectal Resection for Cancer: Prone Position vs. Supine Position
Prospective multicenter randomized controlled trial comparing the prone vs. the supine position of the perineal time of the Miles operation in patients with advanced rectal cancer.
- Trial name
- APPRO (NCT02163785)
- Testing
- Abdominoperineal extra-elevators rectal resection for low lying rectal cancer
- Where
- 19 sites in Spain
- Volunteers
- 280 people
- Sponsor
- Hospital Universitario La Fe
Laparoscopic Hepatectomy, Nerve Block
TAPB Combined With RSB Versus ESPB for Postoperative Analgesia After Laparoscopic Liver Resection
Postoperative pain after laparoscopic hepatectomy is composed of multiple factors, and the peak pain of postoperative pain mainly occurs within the first 24 hours, so it is particularly important to find an appropriate analgesic…
- Trial name
- NCT06133725
- Testing
- erector spinae plane block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhangyi
Breast Cancer, Chemotherapy Effect
Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer
Introduction: Neoadjuvant chemotherapy (NACT) has been the standard therapy for treating patients with locally advanced breast cancer (LABC). Doxorubicin-based regimen showed a clinical response for 70-80%.
- Trial name
- NCT04418089
- Testing
- Simvastatin 40mg
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Non-muscle-invasive Bladder Cancer
A Multi-National Study In Bladder Cancer Patients to Detect Recurrences After TURB (Trans-urethral Resection of the Bladder) Earlier With the Xpert Bladder Cancer Monitor Assay (ANTICIPATE X)
Bladder cancer is the 5th most common cancer in Europe, with more than 151,000 new cases diagnosed in 2012 (4% of the total). Bladder cancer has the highest recurrence rate of any malignancy, often as high as 70% within 5 years…
- Trial name
- ANTICIPATE X (NCT03664258)
- Testing
- Xpert Bladder Cancer Monitor
- Where
- 13 sites in Austria, Czechia and 7 more
- Volunteers
- 852 people
- Sponsor
- Cepheid
Lung Nodule
Single-lumen Endotracheal Intubation in ENB-guided Localization and Resection of Pulmonary Nodules
The goal of this clinical study is to evaluate the practicality, safety, and feasibility of a 'one-stop' single-lumen (SL) endotracheal intubation strategy for patients undergoing wedge resection of early-stage lung nodules with…
- Trial name
- NCT07288255
- Testing
- Single lumen, single-lumen to double-lumen
- Where
- China
- Volunteers
- 375 people
- Sponsor
- Ruijin Hospital
Heart Failure With Preserved Ejection Fraction
Surgical Resection of the Greater Splanchnic Nerve in Subjects Having Heart Failure With Preserved Ejection Fraction
We believe that blocking of the Greater Splanchnic Nerve (GSN) will stop Sympathetic Nervous System (SNS) activity from reaching the splanchnic vessels and result in a redistribution of blood volume back into the splanchnic…
- Trial name
- NCT03715543
- Testing
- Surgical Resection of the Greater Splanchnic Nerve
- Where
- 2 sites in Czechia, Poland
- Volunteers
- 8 people
- Sponsor
- Noblewell
Ptosis, Eyelid
Evaluation of Intraoperative Lagophthalmos Formula
This is a prospective non-randomized study to evaluate the recent intraoperative lagophthalmos formula method for levator resection in determining postoperative eyelid height in congenital ptosis on Egyptian children.
- Trial name
- NCT04291625
- Testing
- Levator muscle resection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Menoufia University
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