Clinical trials: Surgical Resection
Resectable Simultaneous Colorectal Cancer Liver Metastasis
The Outcomes of Laparoscopic Hybrid Surgery Versus Totally Open Surgery
Simultaneous colorectal cancer liver metastasis (SCRLM) is one of the risk factors for poor prognosis in colorectal cancer. Surgical resection of primary and metastatic lesions is the first choice of treatment for patients with…
- Trial name
- NCT06550700
- Testing
- laparoscopic hybrid surgery (LHS)
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Changhai Hospital
Anastomotic Leak, Colorectal Cancer
Predictors of Rescue Surgery, Mortality, and Permanent Stoma After Anastomotic Leak Following Colorectal Cancer Resection
Anastomotic leakage is a serious complication following colorectal cancer resection and may result in emergency reoperation, severe sepsis, death, loss of the colorectal anastomosis, and formation of a long-term or permanent…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Colon Cancer, Postoperative Complication
- Trial name
- leak predictor (NCT07725692)
- Where
- Egypt
- Volunteers
- 3,200 people
- Sponsor
- Alexandria University
Cancer Liver
Retrolaminar Block Versus Subcostal Transversus Abdominis Plane Block in Liver Resection Surgery
Adequate pain control improves postoperative outcomes and is imperative for enhanced recovery after surgery (ERAS) . Open liver resection surgery is associated with intraoperative blood loss, hypotension, coagulopathy, pulmonary…
- Trial name
- NCT06621472
- Testing
- Retrolaminar block group, subcostal TAP technique, thoracic Epidural
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Cervical Intraepithelial Neoplasia, Cervix Neoplasm
Comparing Two Techniques of Haemostasis After Cervical Conization
The LEEP conization is commonly used for cervical pathologies treatment. The techniques for hemostasis usually used are: cautery, Monsel's solution and vaginal pack.
- Trial name
- NCT03293628
- Testing
- Vaginal Packing
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Barretos Cancer Hospital
Bladder (Urothelial, Transitional Cell) Cancer Superficial (Non-Invasive), Transurethral Resection of Bladder Tumor
Evaluation of the Role of Early Second Look TURBT in Management of High Risk Non Muscle Invasive Bladder Cancer
The aim is to evaluate the intraoperative, postoperative and pathologic findings of early second look TURBT and the factors affecting these findings to assess the value of early second TURBT in the management of high risk NMIBC.
- Trial name
- NCT07642102
- Testing
- early second look transurethral resection of bladder tumor
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Lung Cancer
Effect of Pulmonary Rehabilitation on Surgical Outcomes in the Cancer Setting
The goal of this clinical research study is to see if pulmonary rehabilitation can improve patients' lung function, which would increase their chances of becoming eligible for surgery.
- Trial name
- NCT00618553
- Testing
- Questionnaire, Pulmonary Rehabilitation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- M.D. Anderson Cancer Center
Skin Lesion
The Effect of Prophylactic Antibiotics on Surgical Site Infection Lower Limb Skin Excisions
The incidence of surgical site infection (SSI) infection in clean dermatologic surgery is very low, between 1-3%. Studies have demonstrated a much higher infection rate in skin excision surgeries in the lower limbs, up to 10% in…
- Trial name
- NCT03357419
- Testing
- Cephalexin
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pain, Postoperative, Iatrogenic Injury
Effect of Partial Rib Resection On the Control of Post-thoracotomy Pain
The aim of this study is to evaluate the effect of partial rib resection in reducing acute post-thoracotomy pain
- Conditions
- Pain, Postoperative, Iatrogenic Injury, Post-thoracotomy Pain Syndrome
- Trial name
- NCT04990700
- Testing
- Partial rib resection
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Esophageal Stricture, Endoscopic Submucosal Dissection
Local Triamcinolone Injection Combined With Fibrin Glue Spray in Preventing Esophageal Stricture After Big-range Endoscopic Submucosal Dissection for Esophageal Early Cancer
Endoscopic submucosal dissection (ESD) is the main treatment for esophageal early cancer. But post-ESD stricture has a serious impact on quality of life.When the lesion range reaches up to 3/4 circumferential mucosal defect or…
- Conditions
- Esophageal Stricture, Endoscopic Submucosal Dissection, Early Esophageal Cancer or Precancerous Lesions Treated With Endoscopic Resection
- Trial name
- NCT06840561
- Testing
- Local triamcinolone injection combined with fibrin glue spray
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sun Yat-Sen University Cancer Center
Chondrosarcoma, Grade 2
Grade 2 Chondrosarcoma Treated by Intralesional Curettage: Follow-up vs Resection
The goal of this observational study is to assess the oncological outcomes in patients diagnosed with grade 2 chondrosarcoma, treated with intralesional curettage, stratified into two cohorts: those subjected to follow up…
- Trial name
- NCT06714773
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
BPH With Urinary Obstruction
PUL vs TURP in BPH Patients With Urinary Retention
The study will be a prospective, randomized controlled trial comparing prostatic urethral lift (PUL) versus transurethral resection of prostate (TURP) in benign prostate hyperplasia (BPH) patients with urinary retention.
- Trial name
- PULTUR (NCT06037356)
- Testing
- Prostatic Urethral Lift, TURP
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Queen Mary Hospital, Hong Kong
BPH
Global Post-Market Registry Using Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue
The purpose of this study is to evaluate the efficacy of the AQUABEAM System for the treatment of Lower Urinary Tract Symptoms (LUTS) resulting from Benign Prostatic Hyperplasia (BPH).
- Trial name
- OPEN WATER (NCT02974751)
- Testing
- Aquablation
- Where
- 5 sites in Australia, Germany and 3 more
- Volunteers
- 178 people
- Sponsor
- PROCEPT BioRobotics
Pancreatic Adenocarcinoma
Pharmacokinetic Study of Adjuvant Capecitabine After Resection of Pancreatic Adenocarcinoma
The purpose of this study is to evaluate the pharmacokinetics (PK) of adjuvant capecitabine in patients who have undergone proximal pancreatico-duodenectomy.
- Trial name
- NCT00854477
- Testing
- capecitabine
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Colorectal Neoplasms
Prognostic Factors Affecting Outcomes in Multivisceral en Bloc Resection for Colorectal Cancer
Determine clinical and pathological factors associated with perioperative morbidity and mortality, and oncological outcomes after multivisceral en bloc resection in patients with colorectal cancer.
- Trial name
- NCT02859155
- Testing
- Multivisceral en bloc resection surgery
- Volunteers
- 105 people
- Sponsor
- University of Sao Paulo
Rectal Cancer
TaTME Versus Open Intersphincteric Resection After Neoadjuvant Concurrent Chemoradiotherapy.
The two surgical options for lower 1/3 rectal cancer is APR and sphincter sparing procedures. Intersphincteric resection is procedure to treat very low rectal cancer within 2 cm from the dentate line to avoid permanent…
- Trial name
- TaTME (NCT01836926)
- Testing
- Open intersphincteric resection, transanal minimally invasive intersphincteric resection
- Where
- 2 sites in Egypt
- Volunteers
- 110 people
- Sponsor
- Osama Mohammad Ali ElDamshety
Respiration Disorders
Prospective Trial to Reduce Morbidity and Mortality After Lung Surgery in Patients With Reduced Pulmonary Capacity
A fast track recovery program (thoracic epidural anesthesia, carbohydrate drink preoperative, early removal of chest tubes) is evaluated compared to conventional perioperative treatment (patient controlled analgesia, no…
- Trial name
- NCT00530491
- Testing
- Fast track lung surgery
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University of Ulm
Rectal Cancer
Next Generation STAR-TREC (NG-ST) - Organ Preservation in Early Rectal Cancer
This study evaluates whether mesorectal chemoradiotherapy with a limited radiation target volume can achieve a sustained clinical complete response in patients with early-stage rectal cancer, allowing surgery to be safely…
- Trial name
- NG-ST (NCT07483060)
- Testing
- Capecitabine + Radiotherapy, Total Mesorectal Excision (TME)
- Volunteers
- 90 people
- Sponsor
- Vastra Gotaland Region
Hepatocellular Carcinoma
Neoadjuvant HAIC for Resectable Hepatocellular Carcinoma Beyond Milan Criteria
The purpose of this study is to evaluate the efficacy and safety of resection plus neoadjuvant hepatic arterial infusion chemotherapy (HAIC) compared with resection alone in patients with resectable hepatocellular carcinoma…
- Trial name
- NCT03469479
- Testing
- FOLFOX, Hepatic resection
- Where
- 7 sites in China
- Volunteers
- 252 people
- Sponsor
- Sun Yat-sen University
Laparoscopic General, Gynecological and Urologic Surgeries
Evaluation of the Sevoflurane Consumption During General Anesthesia When Using the MemsorbTM Membrane
The study aims at determining whether replacing the classical chemical absorber Dräegersorb 800+ on Dräeger Perseus A500 machines (Dräeger, Lübeck, Germany) by the new membrane technology-based product (Memsorb™, DMF Medical…
- Trial name
- MEMSEV (NCT04539405)
- Testing
- To evaluate sevoflurane consumption when using Memsorb, To evaluate sevoflurane consumption when using classical Dräegersorb
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Thoracic Surgery
Assessment in Patients After Thoracic Surgery
Lung cancer is the leading cause of death in men and the second in women with a 5 year survival in Europe of less than 15%. One of the methods most used for its treatment is pulmonary resection.
- Trial name
- NCT03300622
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
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