Clinical trials: Surgical Wound Healing
Cesarean Section, Surgical Site Infection
Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions
This study is evaluating whether Steri-Strips® provide additional benefits when used after cesarean section (C-section) surgery.
- Conditions
- Cesarean Section, Surgical Site Infection, Wound Dehiscence, Seroma
- Trial name
- STRIP-CS (NCT07686913)
- Testing
- Steri-Strip™ Skin Closures, Standard Cesarean Wound Closure
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- Riverside University Health System Medical Center
Healing Surgical Wounds
Efficacy of Diathermy on Healing Power of Cesarean Section Scar
To compare the effects of electro-surgery on healing power as a primary outcome (from skin to the peritoneum. And volume of blood loss, incision time and postoperative surgical wound pain as secondary outcomes.
- Trial name
- EDHPCS (NCT03988972)
- Testing
- diathermy, scalpel
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pelvic Organ Prolapse, Cystocele
Native Tissue Repair in Pelvic Organ Prolapse -Long-term Results and Risk of Re-operation
This study evaluates the recurrence of pelvic organ prolapse and the rate of re-operation after primary surgery for anterior vaginal wall prolapse with native tissue repair in long term follow-up.
- Trial name
- NCT06744972
- Volunteers
- 392 people
- Sponsor
- Turku University Hospital
Wound Healing, Tooth Extraction Site Healing
Effect of Injectable Platelet Rich Fibrin (i-PRF) on Extraction Socket Healing: A Split-Mouth Randomized Study.
The aim of this study is to compare extraction socket healing (SH) following surgical extraction of lower third molars (LTMs) with and without the application of injectable platelet rich fibrine (i-PRF).
- Trial name
- (i-PRF) (NCT07257328)
- Testing
- Surgical extraction of lower third molars.
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Complications; Perineal Repair
Retrospective Evaluation of Functional and Sexological Results of Surgical Perineal Repair
Vaginal laxity" syndrome is an increasingly frequent reason for gynecological consultations. Patients complain above all of a sensation of excessive vaginal looseness.
- Trial name
- SEX-RPC (NCT04835311)
- Testing
- surgical perineal repair
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Anterior Prolapse Surgery Using the Transobturator Repair by Vaginal Plastron
Transobturator Repair by Vaginal Plastron
The autologous vaginal route consists of repairing the genital prolapse through the vagina using the patient's tissues without a prosthesis. Vaginal prostheses are actually currently prohibited in France [1, 2].
- Trial name
- CYSPTO (NCT05741567)
- Testing
- correction of anterior prolapse
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Non Cardiac Surgery
Presepsin (sCD14-ST) for Prediction of Perioperative Risk - MET-REPAIR Nested Cohort Study
Multicentre international prospective cohort study designed to evaluate whether preoperative presepsin (sCD14-ST) is associated with the composite endpoint: all-cause mortality and major adverse cardiovascular or cerebrovascular…
- Trial name
- P^3-MET-REPAIR (NCT03489486)
- Where
- Germany
- Volunteers
- 1,695 people
- Sponsor
- University Hospital Heidelberg
Lumbar Disc Herniation
Preoperative Magnetic Resonance Imaging Abnormalities Predictive of Lumbar Herniation Recurrence
There are currently no standard criteria for evaluating the risk of recurrent disk herniation following surgical repair. This study investigated the predictive values of five presurgical imaging parameters, paraspinal muscle…
- Trial name
- NCT05246241
- Testing
- magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people
- Sponsor
- Ataturk University
Wound Healing, Surgical Wound Infection
The Application of Infrared Thermography in the Prediction of Skin Healing in Surgery
This study investigates whether infrared thermography, a harmless and non-invasive thermal camera technique, can help monitor how surgical wounds heal after skin surgery.
- Conditions
- Wound Healing, Surgical Wound Infection, Postoperative Complications, Skin Neoplasms
- Trial name
- THERMS (NCT07524062)
- Testing
- Infrared thermography
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bleeding, Healing Surgical Wounds
Effect of Inula Viscosa Extract on Postoperative Bleeding and Healing After Lower Third Molar Surgery
In oral surgery, the operation of the impacted third molar is one of the most common surgical procedures performed by oral and maxillofacial surgeons .Several attempts have been made to reduce the postoperative outcome of the…
- Trial name
- NCT06947603
- Testing
- inula viscosa extract, no inula viscosa extract
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Al-Wataniya University
Absent Pulmonary Artery
A Study Of Surgical Repair Of Discontinuous Branching Pulmonary Arteries
The purpose of this study is to test the safety and performance of a new blood vessel graft, called the ATEV. The graft is designed to reconnect the heart to the lungs and to grow as the child grows, which may eliminate the need…
- Trial name
- NCT07785661
- Testing
- Acellular Tissue Engineered Vessel (ATEV) Conduit
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Joseph Dearani
Chronic Subdural Hematoma, Subdural Hematoma
Non-Thermal Plasma to Reduce Recurrence in Chronic Subdural Hematoma
The goal of this randomized controlled trial is to evaluate whether the adjuvant application of non-thermal plasma (NTP) during standard surgical drainage of chronic subdural hematoma (cSDH) can reduce the recurrence rate at 6…
- Conditions
- Chronic Subdural Hematoma, Subdural Hematoma, Recurrence, Postoperative Complications
- Trial name
- NCT07656818
- Testing
- Standard Surgery Protocol, Non-Thermal Plasma
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Benjamín Gonzalo Rodríguez Méndez
ACL - Anterior Cruciate Ligament Deficiency
5 Years' Follow-up Assessment of Surgical Repair for ACL Proximal Rupture
Isolated ruptures of ACL (anterior cruciate ligament) are ligament injuries that can be proximal, central or distal. Treatment of patients with proximal lesions should be graded.
- Trial name
- RUPTUPROX (NCT06178497)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Caudal Block
Methylprednisolone Versus Dexamethasone in Pediatric Caudal Block
This randomized, double-blind, controlled bi-center study was designed to compare the postoperative analgesic efficacy of dexamethasone and methylprednisolone in caudal block for children undergoing hypospadias surgical repair…
- Trial name
- NCT05717374
- Testing
- caudal block using dexamethasone, caudal block using methylprednisolone
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Lateral Ankle Instability, Chronic Lateral Ankle Instability
Brostrom Chronic Lateral Ankle Instability Repairs Augmented With BioBrace®
The purpose of this investigation is to evaluate pre- and post-operative patient reported outcomes and functional scores after open non-augmented Broström repair or open Broström repair augmented with the BioBrace Implant.
- Conditions
- Lateral Ankle Instability, Chronic Lateral Ankle Instability, Brostrom Procedure, ATFL
- Trial name
- NCT07708584
- Testing
- Standard Brostrom Repair, Brostrom repair with augmentation
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Wound Healing
Effects of CGF and Collagen Fleece on Palatal Donor Site Healing: A Randomized Clinical Trial
This study investigated whether applying Concentrated Growth Factor (CGF) or Collagen Fleece (CF) to the palatal donor site after autogenous soft tissue graft harvesting could improve wound healing and reduce postoperative…
- Trial name
- PAL-HEAL (NCT07367165)
- Testing
- Concentrated Growth Factor (CGF), Collagen Fleece (CF), Collagen Sponge (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Inonu University
Hidradenitis Suppurativa (HS)
Pelashield™ PainGuard™ vs Restrata® in HS Surgery
Hidradenitis Suppurativa (HS) is a long-lasting skin condition that causes painful lumps and infections. In severe cases, patients need surgery to remove the affected skin.
- Trial name
- NCT07316192
- Testing
- Pelashield Painguard
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Surgery
Maestro LIFT-OFF: Surgical Assistance Device in Abdominal Laparoscopic Surgery
The objective of the study is to provide evidence for the safety and effectiveness of the Maestro Platform for surgical assistance in abdominal laparoscopic surgery.
- Trial name
- Maestro (NCT05243433)
- Testing
- Laparoscopic surgery using the Maestro Platform
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Moon Surgical
Pelvic Organ Prolapse
Prospective Assessment of Robotic Sacrocolpopexy: a European Multicentric Cohort (PARSEC)
The purpose of this study is to prospectively assess the outcomes of robotic sacrocolpopexy for repair of pelvic organ prolapse in high volume european centers.
- Trial name
- PARSEC (NCT01598467)
- Testing
- Robotic assisted sacrocolpopexy (RASC)
- Where
- Ireland
- Volunteers
- 300 people
- Sponsor
- Femke van Zanten
Third Molar Surgery, Post Operative Analgesia
'Propolis Versus Chlorhexidine Gluconate on Wound Healing After Third Molar Surgery: a Randomized Controlled Trial'
The goal of this study is to examine the effects of propolis gargle on wound healing following third molar surgery and to compare it with chlorhexidine gluconate.
- Trial name
- NCT07364253
- Testing
- Third molar Surgery with propolis gargle, Third molar surgery with chlorhexidine gluconate
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ataturk University
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