Clinical trials: Surveillance Protocol Biopsy
Barrett's Esophagus
"Acetic Acid Chromoendoscopy in Barrett's Esophagus Surveillance
Neoplasia in Barrett's esophagus could be missed during routine random biopsies. We propose a study using chromoendoscopy with Acetic Acid to increase the yield of biopsies in detecting neoplasia.
- Trial name
- NCT02614703
- Testing
- Chromoendoscopy using Acetic Acid 2.5%, Standard random esophageal biopsies
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- DHR Health Institute for Research and Development
Surveillance Protocol Biopsy
Protocol-Specified Modification of Immunosuppression Directed to Protocol Biopsy in Kidney Transplantation
The risk-benefit of surveillance-protocol biopsy (SPBx) in kidney transplantation remains unclear. The study aims to compare outcomes of recipients with SPBx approach to recipients with standard approach which allograft biopsy…
- Trial name
- NCT02294097
- Testing
- Surveillance protocol kidney allograft biopsy
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
Prostate Cancer
Virtual Prostate Biopsy Protocol for Patients on Active Surveillance and at Risk of Prostate Cancer
The purpose of this study is to examine the use of MRI surveillance for patients with no prostate cancer, potential prostate cancer, or diagnosed low-grade prostate cancer.
- Trial name
- NCT03823001
- Testing
- virtual biopsy (VB) monitoring protocol
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Barrett Esophagus
"Using Dilute Vinegar to Find Changes in Cells During Endoscopy for Patients With Barrett's Oesophagus" (The ABBA Study)
Problem statement Barrett's oesophagus is a pre-cancerous condition affecting 375,000 people in the U.K. There is a 0.5-3% yearly risk of progressing to oesophageal cancer, from which only 5% of patients will survive for 5 years…
- Trial name
- ABBA (NCT02407392)
- Testing
- Acetic Acid, Non targeted quadrantic biopsies
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Liver Allograft, Liver Diseases
Everolimus bAsed caLcineurin inhibiTor frEe immunosuppRession oNe Year AfTer lIver transplantatiON (ALTERNATION)
The overall aim of this study is nephroprotection based on a calcineurin inhibitor (CNI)-free therapy beyond year one after orthotopic liver transplantation (OLT) in highly pre-selected patients with low rejection risk.
- Conditions
- Liver Allograft, Liver Diseases, Liver Transplantation
- Trial name
- ALTERNATION (NCT07739914)
- Testing
- Everolimus, Tacrolimus or Cyclosporine
- Where
- 16 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Hannover Medical School
Barrett Esophagus, Barretts Esophagus With Dysplasia
Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance
The purpose of this research study is to learn about the best approach to sample patients with known or suspected Barrett's esophagus (BE) by comparing the standard Seattle biopsy protocol to sampling using wide area…
- Conditions
- Barrett Esophagus, Barretts Esophagus With Dysplasia, Esophageal Adenocarcinoma
- Trial name
- SWAT-BE (NCT05530343)
- Testing
- Seattle protocol, WATS3D brushings
- Where
- 14 sites in United States
- Volunteers
- 2,298 people
- Sponsor
- University of Colorado, Denver