Clinical trials: Survival Analysis
Breast Cancer, Malignant Neoplasm of Breast
A Real-life Study to Understand the Use and Effects of Palbociclib in US Patients With Breast Cancer
Palbociclib, the first oral CDK4/6 inhibitor, is an approved medicine indicated for the treatment of a kind of advanced/metastatic breast cancer (MBC), called hormone receptors positive (HR+)/ Human epidermal growth factor…
- Trial name
- NCT06495164
- Testing
- Palbociclib, Aromatase inhibitor, Ribociclib
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Pfizer
Cancer
Prognosis and Survival Estimates in Palliative Therapy
The accuracy of clinical survival estimates is tested in comparison to objective prognostic scores.
- Trial name
- NCT00871520
- Testing
- no specific interventions
- Where
- 3 sites in Germany
- Volunteers
- 612 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Osteoarthritis
Cryopreserved Human Meniscus Transplantation
The purpose of this study is to determine the long-term survivorship and clinical outcomes of all cryopreserved meniscus transplants performed by Dr. Frank Noyes.
- Trial name
- NCT02319811
- Testing
- Cryopreserved meniscus transplants
- Volunteers
- 76 people
- Sponsor
- Cincinnati Sportsmedicine Research and Education Foundation
Periprosthetic Hip Infection
Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Hip Infection: a Microdialysis Study
This study aims to use the technique of microdialysis to analyse the intraarticular space of the hip joint after removal of a periprosthetic joint infection affected endoprosthesis and implantation of an antibiotic-containing…
- Trial name
- PJI_H_MD (NCT07299591)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Ankle Brachial Index
Ankle Brachial Index Combined With Serum Uric Acid Levels Improve Prediction All Cause Mortality and Cardiovascular Mortality in the Elderly Chinese Population
Peripheral arterial disease (PAD) is a common clinical manifestation of the systemic atherosclerotic process, and the ankle brachial index (ABI) is an ideal tool to diagnose PAD.
- Trial name
- abilities (NCT03616418)
- Testing
- antiplatelet drugs;statins;antihypertensive drugs
- Volunteers
- 3,026 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Sepsis, Blood Coagulation Disorders
Analysis of the Coagulopathy Developed by COVID-19 Infected Patients
Increased D-dimers at admission of COVID-19 infected patients entering hospital due to a severe disease is a risk factor for death.
- Conditions
- Sepsis, Blood Coagulation Disorders, Thrombin, Disseminated Intravascular Coagulation
- Trial name
- COVID-TGT (NCT04356950)
- Testing
- Thrombin generation test assay, Fibrin generation markers assays
- Where
- 4 sites in France
- Volunteers
- 175 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Triple Negative Breast Cancer, Metastatic Triple-negative Breast Cancer
HEADWATERS: Gemcitabine vs Paclitaxel in Metastatic Triple-Negative Breast Cancer in Women of African Ancestry.
The goal of this clinical trial is to learn if Gemcitabine, a chemotherapy drug that is usually used to treat breast cancer after other treatments have failed, is better at treating triple negative breast cancer in women of…
- Trial name
- NCT07528768
- Testing
- Gemcitabine (1000 mg/m^2), Paclitaxel 80 mg/m2 weekly
- Where
- 3 sites in Barbados, Ghana and 1 more
- Volunteers
- 750 people
- Sponsor
- The University of The West Indies
Anterior Cruciate Ligament Rupture, Surgery
ALL Ultrasound Predicts the Success of ACL Repair?
This case series evaluates whether patients with an anterior cruciate ligament (ACL) repair have better outcome if the anterolateral ligament (ALL) was repaired or not considering the ultrasound (US) pre-surgical recommendation.
- Trial name
- ALL_US (NCT04373408)
- Testing
- ACL repair without anterolateral repair, ACL repair with anterolateral repair
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Adrien Schwitzguebel
Glioma (Any Grade) in the Brain
Study on The Sensitizing Effect of Sonodynamic Therapy on The Treatment of Brainstem Glioma With Radiotherapy and Chemotherapy and Survival Analysis
1.Brief Introduction to the Research Background: You are invited to participate in a clinical study initiated by the First Affiliated Hospital of Zhengzhou University and chaired by Professor Zheng Yingjuan at our center.
- Trial name
- NCT06999148
- Testing
- Sonodynamictherapy, Radiotherapy plus temozolomide
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Yingjuan Zheng
Pancreatic Cancer
Pancreatic Resection in Fit Octogenarians With Nonmetastatic Pancreatic Cancer
This study looks at how different treatment approaches affect survival in older people with pancreatic cancer that has not spread to other parts of the body.
- Trial name
- PRONPaC (NCT07542782)
- Testing
- All types of surgical tumor resection procedures with curative intent, No surgical resection
- Where
- Germany
- Volunteers
- 2,048 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Renal Cell Carcinoma
Retrospective Analysis Of Progression Free Survival And Overall Survival In A National Cohort Of Patients With Metastatic Renal Cell Carcinoma Treated In Denmark From 2006-2010. DARENCA Study 2.
Non-interventional study. Data obtained by patient chart reviews. Retrospective analysis of progression free survival, time to treatment failure and overall survival in a national cohort of patients with metastatic renal cell…
- Trial name
- NCT01339962
- Testing
- Non-interventional
- Where
- Denmark
- Volunteers
- 1,073 people
- Sponsor
- Pfizer
The Aim of This Study is to Determine the Influence of BMI and Lymph Node Status on OS in CRC Patients in the Long Term
BMI and Lymph Node Count in Colorectal Cancer
Background and aim: Colorectal Cancer (CRC) is one of the most frequent cancer entities in the western world. It is known that obesity is one of the major risk factors for CRC.
- Trial name
- NCT06334926
- Testing
- no intervention, retrospective data analysis
- Where
- Austria
- Volunteers
- 1,192 people
- Sponsor
- Klinikum Floridsdorf
Pancreatic Cancer, Neoadjuvant Chemotherapy
Multimodal Therapy Impact on Pancreatic Cancer Survival
The goal of this retrospective cohort study is to analyze change of treatment strategies affect the survival outcomes in patients of pancreatic cancer who received curative-intent treatment.
- Conditions
- Pancreatic Cancer, Neoadjuvant Chemotherapy, Pancreatectomy
- Trial name
- MMTIPS (NCT06938906)
- Where
- Taiwan
- Volunteers
- 405 people
- Sponsor
- National Cheng Kung University
Bone Metastases
Analysis of Intramedullary Nail and Prosthetic Reconstruction After Surgical Treatment of Bone Metastases of Proximal Femur
The investigators will collect data of patients treated surgically for impending or pathological fracture of the proximal femur due to bone metastases between 01/01/2000 and 31/12/2023 with IMN or THA or HHA or MegaTHA or Mega.
- Trial name
- NCT06918860
- Testing
- Analysis
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Costantino Errani
Hepatocellular Carcinoma (HCC)
Efficacy Evaluation of Microwave Ablation Assisted by Diaphragm Hydrodissection for Hepatocellular Carcinoma and Comparative Analysis With Surgical
The goal of this observational study is to evaluate the local efficacy and safety of hydrodissection-assisted microwave ablation for patients with hepatocellular carcinoma, and to compare its therapeutic outcomes with surgical…
- Trial name
- NCT07815054
- Testing
- Microwave Ablation Assisted by Diaphragm Hydrodissection, Surgical Resection
- Volunteers
- 200 people
- Sponsor
- The First Hospital of Jilin University
Sepsis-related Myocarditis
Sepsis and Myocarditis
This prospective cohort study aims to investigate the cardiac manifestations of sepsis and their influence on disease outcomes among adult patients at Jimma University Medical Center, Ethiopia, from May 2025 to May 2026.
- Trial name
- NCT07079605
- Testing
- Standard treatment for sepsis of any focus, Treatment for the sepsis with standard management of cardiac failure
- Where
- Ethiopia
- Volunteers
- 226 people
- Sponsor
- Jimma University
Critical Limb Ischemia, Peripheral Arterial Disease
Foot Perfusion Analysis to Predict Limb Salvage
This study aims at evaluating the correlation between foot perfusion on angiographies performed before and after revascularization and limb salvage in patients with critical limb ischemia.
- Trial name
- DELTA-PERF (NCT03810469)
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier de Valenciennes
Neoplasms, Lung, Carcinoma, Non-Small Cell Lung
A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations
Objective: the objective of this study in china is to clarify, whether the overall survival is different between previously untreated stage IIIB/IV lung adenocarcinoma with EGFR mutations receiving first-line erlotinib plus…
- Conditions
- Neoplasms, Lung, Carcinoma, Non-Small Cell Lung, Drug Therapy, Genes, EGFR
- Trial name
- NCT01131429
- Testing
- Erlotinib, Docetaxel, Cisplatin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Esophageal Cancer
Complete Clinical Responders to Definite Chemoradiation in Esophageal Cancer : a Survival Analysis
The aim of this study is to identify prognostic factors for outcome in patients being complete clinical responders with chemoradiation or radiation for esophageal cancer
- Trial name
- CRCRT-EC (NCT01525953)
- Testing
- Chemotherapy, Radiotherapy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Oscar Lambret
Amyotrophic Lateral Sclerosis
Human Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis (ALS)
Primary aim of the trial 1. to verify safety and tolerability of expanded human fetal neural stem cells 2. to verify safety and tolerability of a microsurgery human fetal neural stem cells transplantation model 3.
- Trial name
- hNSCALS (NCT01640067)
- Testing
- Human Neural Stem Cells
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Azienda Ospedaliera Santa Maria, Terni, Italy