Clinical trials: Suspected Lung Cancer
Lung Cancer, Mesothelioma
Implantable Microdevices for in Situ Evaluation of Drug Responses in Lung Cancer
This research is being done to study the safety and feasibility of implanting and retrieving a microdevice that releases microdoses of 20 specific drugs or drug combinations as a possible tool to evaluate the effectiveness of…
- Conditions
- Lung Cancer, Mesothelioma, Suspected Lung Cancer, Suspected Mesothelioma
- Trial name
- NCT07892300
- Testing
- Implantable Micro- drug delivery Microdevice (IMD)
- Volunteers
- 20 people
- Sponsor
- Oliver Jonas
Lung Cancer (Suspected or Confirmed), Thoracoscopic Lobectomy
Right Ventricular Afterload Indices in Lung Surgery
Lung cancer is a leading cause of cancer death in Scotland and the UK. Surgery, typically using a keyhole approach, provides the best chance of cure.
- Conditions
- Lung Cancer (Suspected or Confirmed), Thoracoscopic Lobectomy, One Lung Ventillation (OLV)
- Trial name
- RAILS (NCT07812207)
- Testing
- Contrast cardiac magnetic resonance imaging, Right heart catheterisation, Perioperative plasma sampling
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Lung Cancer (Suspected or Confirmed)
Effect of a Music Intervention in Reducing Distress and Pain in Patients With Lung Cancer Undergoing Mini-invasive Surgery
This study aims at evaluating whether music therapy intervention is effective in decreasing psychological (distress) and physical symptoms (pain) in patients with suspected or diagnosed lung cancer undergoing minimally invasive…
- Trial name
- NCT07235098
- Testing
- Music therapy intervention
- Where
- Switzerland
- Volunteers
- 74 people
- Sponsor
- Oncology Institute of Southern Switzerland
Suspected Lung Cancer
Implementation of Smoking Cessation Support During Lung Cancer Workup
The aim of the present project is to implement smoking cessation support in hospital-based lung cancer workup. The effect on 1) patients' smoking cessation attempts, motivation, quality of life and psychosocial consequences of…
- Trial name
- NCT05192031
- Testing
- Smoking cessation support
- Where
- Denmark
- Volunteers
- 86 people
- Sponsor
- Vejle Hospital
Lung Nodules, Lung Cancer Screening
ctDNA Mutations and Methylation Status for Early Detection of Lung Cancer in Patients With Suspicious Lung Nodules
Lung Cancer is common in Asia and is different from lung cancer from Western countries in terms of lung cancer epidemiology and management.
- Conditions
- Lung Nodules, Lung Cancer Screening, Suspected Lung Cancer
- Trial name
- NCT07615556
- Testing
- ctDNA mutations and methylation with SPOTMAS Lung assays, Non-contrast LDCT Thorax scans
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Pulmonary Nodule, Suspected Lung Cancer
Preoperative Decision-Making in Patients With Pulmonary Nodules Suspected of Lung Cancer
Patients with pulmonary nodules that are highly suspected to be lung cancer often need to make important treatment decisions before a definite pathological diagnosis is available.
- Conditions
- Pulmonary Nodule, Suspected Lung Cancer, Preoperative Decision-Making
- Trial name
- NCT07590596
- Testing
- Questionnaire-Based Decision-Making Assessment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Lung Cancer (Diagnosis), Lung Cancer (Suspected or Confirmed)
A Study Measuring Markers of Airway Inflammation in Breath Samples From People With Respiratory Diseases and Healthy Volunteers.
Lung cancer remains the leading cause of cancer-related death in the UK, with over 35,000 deaths annually and most cases diagnosed at a late stage.
- Conditions
- Lung Cancer (Diagnosis), Lung Cancer (Suspected or Confirmed), Healthy, Pneumonia
- Trial name
- VICTORY 2 (NCT07426718)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Lung Cancer (Suspected or Confirmed), Cryoablation
One-stop Diagnosis and Treatment for Suspected Lung Cancer: Combined RBS, nClE, OBCT and Ablation
Using RBS as the navigation and treatment platform, precisely navigate to the target lesion. Utilize r-EUBS and nCLE to identify the lesion, and when the confocal AI model recognizes the lesion as malignant, perform a biopsy.
- Conditions
- Lung Cancer (Suspected or Confirmed), Cryoablation, Robotic Bronchoscopy System, Confocal Laser Endomicroscopy
- Trial name
- One-stop (NCT07521618)
- Testing
- Ablation
- Volunteers
- 30 people
- Sponsor
- Guangzhou Medical University
Patients With Suspected Non-small Cell Lung Cancer (NSCLC) at Clinical Stage T1
Anesthesia Comparison in Early-stage Small NSCLC: A Multicenter RCT
This study is a prospective, randomized, controlled study, which intends to enroll patients with suspected early-stage NSCLC (non-small cell lung cancer) with a diameter of ≤ 3 cm as research subjects.
- Trial name
- NCT07327736
- Testing
- Non-intubated video-assisted thoracic surgery with spontaneous breathing (NIVATS)
- Volunteers
- 410 people
- Sponsor
- Tang-Du Hospital
Small Pulmonary Nodules, Pulmonary Nodule Localization
Monarch Robotic Bronchoscopy for Lung Nodule ICG Dye Marking Before VATS
This is a single-center, prospective, single-arm clinical study conducted at Beijing Cancer Hospital to evaluate the effectiveness, safety, and learning curve of preoperative indocyanine green (ICG) dye marking mixed with…
- Conditions
- Small Pulmonary Nodules, Pulmonary Nodule Localization, Lung Cancer (Suspected or Confirmed), Video-assisted Thoracoscopic Surgery (VATS)
- Trial name
- REALM (NCT07177924)
- Testing
- Monarch RAB with CBCT-guided ICG Dye Marking
- Volunteers
- 50 people
- Sponsor
- Peking University Cancer Hospital & Institute
Suspected Malignant Lung Neoplasm, Pleural Effusion
First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.
Non randomized study with two groups. The study group includes patients with suspected malignant pleural effusion, in whom the investigation of pleural effusion begins directly with pleural biopsy by Local Anesthesia Thoracoscopy…
- Conditions
- Suspected Malignant Lung Neoplasm, Pleural Effusion, Pleural Effusion, Malignant, Mesothelioma, Malignant
- Trial name
- FLAT (NCT06946498)
- Testing
- Local Anesthesia Thoracoscopy, Pleuroscopy with Rigid Thoracoscope and Forceps biopsies
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Suspected Lung Cancer
Distress and Quality of Life During the Diagnostic Phase of a Suspected Serious Lung Disease
The purpose of this study is to gain insight in the distress experience and quality of life of patients suspected of having a serious lung disease during the diagnostic phase and the period between diagnosis and start of treatment
- Trial name
- DIADISS (NCT02060877)
- Testing
- observational study: use of patient questionnaires
- Where
- 8 sites in Belgium
- Volunteers
- 105 people
- Sponsor
- Universiteit Antwerpen
Suspected Left Adrenal Gland Metastasis in Lung Cancer
EUS-B-FNA vs EUS-FNA for Left Adrenal Gland Analysis in Lung Cancer Patients
The purpose of this study is to compare EUS-B-FNA (using the EBUS scope)with EUS-FNA for left adrenal gland analysis in lung cancer patients.
- Trial name
- NCT02538380
- Testing
- EUS-B-FNA followed by EUS-FNA for LAG analysis
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)