Clinical trials: Sutures, open to volunteers
Vascular Closure Device, Femoral Arteriotomy Closure
Safety and Effectiveness Clinical Study of Novelrad Vascular Closure System (NVCS)
This study evaluates the safety and effectiveness of the Novelrad Vascular Closure System (NVCS), a suture-mediated vascular closure system, in achieving post-procedure hemostasis in subjects undergoing interventional…
- Conditions
- Vascular Closure Device, Femoral Arteriotomy Closure, Femoral Access Site Closure
- Trial name
- NCT07862309
- Testing
- Novelrad Vascular Closure System (NVCS)
- Volunteers
- 65 people
- Sponsor
- Novelrad Ltd.
RCC, Renal Cell Cancer
Comparison of Outcomes and Surgical Time Between Cortical and Medullary Suture vs. Medullary-Only Suture: Cortex Clinical Trial
Renal function preservation is a growing concern in the surgical management of kidney tumors, particularly with the rise in chronic kidney disease worldwide.
- Trial name
- CORTEX (NCT07190638)
- Testing
- Medullary-only suturing (single-layer), Suture, Medullary and cortical suturing (two-layer)
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- Brazilian Institute of Robotic Surgery
Ostomy - Ileostomy or Colostomy, Stoma Complications
Suture Choice for Ostomy Creation
The goal of this clinical trial is to learn whether chromic gut or polyglactin 910 suture results in fewer stoma complications when used to mature an enterostomy in patients undergoing planned ostomy creation.
- Conditions
- Ostomy - Ileostomy or Colostomy, Stoma Complications, Stoma Site Dermatitis, Stoma Site Infection
- Trial name
- NCT07900711
- Testing
- Chromic Gut Suture, Polyglactin 910 Suture
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Southern California
Seroma
fixAtion of skiN Flaps After Mastectomy Using ruNning or Interrupted suturEs for Combatting Seroma
Rationale: Flap fixation significantly reduces the incidence of seroma formation after mastectomy. Therefore, research should focus on finding the most optimal way to secure the skin flaps to the pectoral muscle.
- Trial name
- ANNIE (NCT05941351)
- Testing
- flap fixation
- Where
- Netherlands
- Volunteers
- 361 people
- Sponsor
- Zuyderland Medisch Centrum
Anastomotic Leak, Colon Cancer
Leakage Rate of Ileo-COlic Sutured Anastomosis After Right Hemicolectomy
The primary aim of the study is to show that the ileo-colic anastomosis leakage rate until the first 30 days after surgery using MonoPlus® suture material for anastomosis construction after right hemicolectomy is not inferior to…
- Conditions
- Anastomotic Leak, Colon Cancer, Right Hemicolectomy
- Trial name
- LICOSARH (NCT07132970)
- Testing
- Monoplus Suture Material
- Where
- 4 sites in Germany
- Volunteers
- 249 people
- Sponsor
- Aesculap AG
Surgical Site Infection
Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
The aim of the study is to elucidate, if the colonization of bacteria is lower on the Novosyn® CHD suture compared to uncoated Polyglactin 910 suture, which will be assessed by the incidence of surgical site infections (SSI: A1…
- Trial name
- POLYNOVO-CHD (NCT05966961)
- Testing
- Novosyn® in emergency or elective laparotomy or laparoscopic surgery, Polyglactin 910 in emergency or elective laparotomy or laparoscopic surgery
- Where
- 4 sites in Italy, Spain
- Volunteers
- 2,998 people
- Sponsor
- Aesculap AG
Meniscal Extrusion, Meniscus Injury
Transtibial Pull Out Method Versus Suture Anchor Method for Meniscus Extrusion
The concept of meniscal extrusion has recently been recognized as an important pathological condition associated with meniscal dysfunction.
- Trial name
- NCT06906783
- Testing
- Transtibial Pull Out Method, Suture Anchor Method
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ataturk University
Inguinal Hernia, Hydroceles
Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures
The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries.
- Conditions
- Inguinal Hernia, Hydroceles, Surgical Site Infection
- Trial name
- NCT07346742
- Testing
- Antimicrobial-coated sutures, Intravenous Cefuroxime
- Where
- Nigeria
- Volunteers
- 174 people
- Sponsor
- Olawumi Olajide
Precancerous Lesion of Colon
Suturing Through-the-scope System Used for Prophylactic Closure of Colonic Post-ESD Defects
The goal of this study is to perform a randomized trial to compare a new through-the-scope suturing system and conventional clips for closure of defect after ESD for 30-60 mm colonic polyps.
- Trial name
- STITCH (NCT06443047)
- Testing
- TTS suturing system
- Volunteers
- 66 people
- Sponsor
- Istituto Clinico Humanitas
Laparotomy, Dehiscence Wound
Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT
This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory…
- Conditions
- Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen
- Trial name
- NCT06043414
- Testing
- triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Southern California
Benign Ovarian Cyst
Comparison of Hemostatic Agent to Suture in Terms of Hemostatic Function and Preservation of Ovarian Function
This study aims to evaluate the efficacy of preservation of ovarian function, hemostasis, and safety of a hemostatic agent versus suturing during laparoscopic ovarian cystectomy for ovarian endometriosis.
- Trial name
- PRAHA-2 (NCT04643106)
- Testing
- Hemostatic agent (EVICEL®) application during laparoscopic ovarian cystectomy, suturing with barbed sutures during laparoscopic ovarian cystectomy
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
ESD Defect, Gastric Epithelial Lesion
Su2ura ESD Closure Pilot Study
This study is a single-center, prospective, single-arm, non-blinded first-in-human (FIH) early feasibility study intended to evaluate the short-term safety and technical feasibility of closure of gastric post-ESD defects using a…
- Trial name
- NCT07843719
- Testing
- Su2ura® GI system
- Volunteers
- 5 people
- Sponsor
- Chinese University of Hong Kong
Obesity
National Registry of Obesity Treatment by Endosleeve
Obesity and overweight have emerged as public health problems of a pandemic nature, significantly reducing the life expectancy of those affected.
- Trial name
- NCT06657339
- Testing
- Therapeutic endoscopy endosleeve using a gastric suturing device (OverStitch™/Endomina™)
- Volunteers
- 354 people
- Sponsor
- Société Française d'Endoscopie Digestive
Wound Healing
Basement Membrane Regeneration for Wound Repair
This study is a prospective, multicenter, real-world observational study. It aims to evaluate the effectiveness and safety of autologous basement membrane regeneration technology (epidermal basal cell suspension prepared using a…
- Trial name
- NCT07551284
- Testing
- Autologous Epidermal Basal Cell Suspension
- Volunteers
- 1,000 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Patent Foramen Ovale (PFO)
Safety and Efficacy of the Patent Foramen Ovale Suture System for the Closure of Patent Foramen Ovale
A prospective, multicenter, randomized controlled, non-inferiority clinical trial to evaluate the efficacy and safety of the patent foramen ovale suture system in the closure treatment of patent foramen ovale.
- Trial name
- NCT07726927
- Testing
- Patent Foramen Ovale Suture System, Amplatzer PFO Occluder
- Volunteers
- 244 people
- Sponsor
- Shenzhen Bihe Medical Co., Ltd
Midwifery Education, Suture
The Effect of Hand Sewing Practices on Suturing Skills
The overall aim of this study was to evaluate the effects of hand-held suture exercises on non-locking continuous suture skills used in episiotomy repair in midwifery students.
- Conditions
- Midwifery Education, Suture, Skill Performance
- Trial name
- NCT07236853
- Testing
- Hand Sewing Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 83 people
- Sponsor
- Melek Şen Aytekin
Incisional Hernia After Midline Laparotomy, Quality of Life (QOL)
NoPro - Norwegian Hernia Prophylaxis Study
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh.
- Conditions
- Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
- Trial name
- NoPro (NCT06858020)
- Testing
- Prophylactic polypropylene onlay mesh
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Innlandet HF
Minor Trauma Requiring Suturing, Pain
AI-Assisted Patient Education Before Suturing in Minor Trauma
Patients scheduled to undergo suturing for minor trauma in the emergency department frequently experience anticipatory pain and anxiety before the procedure.
- Conditions
- Minor Trauma Requiring Suturing, Pain, Anxiety
- Trial name
- NCT07872215
- Testing
- AI-Assisted Pre-Suturing Patient Education
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Gazi University
VATS, Lung Hernia
The Application Value of Intercostal Suturing in Preventing Postoperative Thoracoscopic Lung Resection Chest Wall Pulmonary Hernia
The purpose of this trial is to understand whether intercostal suture can effectively prevent postoperative chest wall lung herniation, mainly to verify the following questions Can intercostal suture reduce postoperative chest…
- Trial name
- NCT06924515
- Testing
- Intercostal suture
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Mingjian Ge
Patella Fracture
High-Strength Suture vs. Traditional Tension Band for Patellar Fractures
This prospective cohort study aims to evaluate the clinical efficacy of high-strength suture modified tension band fixation in treating patellar fractures and compare it with traditional screw-cable tension band fixation.
- Trial name
- NCT07248982
- Testing
- High-Strength Suture Modified Tension Band Fixation, Screw-Cable Tension Band Fixation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fuzhou University Affiliated Provincial Hospital