Clinical trials: Swelling, active
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Chronic Venous Disease
Evaluation of Lymphatic Response to Physiotherapy in Patients With Swelling Associated With Superficial Venous Disease
This study seeks to demonstrate the effect of advanced pneumatic compression in treatment naïve patients with CEAP C3 and C4 chronic venous disease.
- Trial name
- NCT07165340
- Testing
- Indocyanine Green near infrared fluorescence imaging, advanced pneumatic compression, Duplex ultrasound
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Recovery, Total Knee Arthroplasty
Nutrition and Swelling
This study is looking at whether taking a nutritional supplement before and after knee replacement surgery affects normal recovery.
- Trial name
- NCT07899762
- Testing
- Xcelerated Recovery Nutritional Supplement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aseptic Revision Knee Arthroplasty, Stiffness Following Revision Knee Arthroplasty
Does Joint Immobilization Following Revision Total Knee Arthroplasty Improve Range of Motion Following Surgery?
The goal of this study is to evaluate if knee immobilization for 10 days following revision total knee arthroplasty (rTKA) improves knee joint range of motion at 3 months postoperatively compared to standard of care postoperative…
- Trial name
- NCT07552415
- Testing
- Knee immobilizer, No Knee Immobilizer
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis (OA) of the Hip
TED Stocking vs. Reparel Garment After Hip Replacement
This randomized, prospective study compares the effectiveness of a novel bioactive garment (Reparel Leg Sleeve) versus standard TED compression stockings in reducing postoperative leg swelling, pain, and deep vein thrombosis…
- Trial name
- NCT07246200
- Testing
- Reparel Bioactive Sleeve, TED Stocking
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Reparel
Unilateral Breast Neoplasms
Arm Swelling Occurence in Breast Cancer Patients With Nodal Radiotherapy: Impact of Informing Them of AI-predicted Risk
Radiotherapy after breast cancer surgery can lead to side effects like arm lymphedema (arm swelling). Lymphedema can cause long-term discomfort and affect quality of life.
- Trial name
- PRE-ACT-01 (NCT07187726)
- Testing
- XAINET AI tool
- Where
- 27 sites in France, Netherlands
- Volunteers
- 724 people
- Sponsor
- UNICANCER
Root End Resection, Periapical Lesion
Effect of Local Use of Non-steroidal Anti-inflammatory Agent (Diclofenac Sodium) With and Without Hyaluronidase on Post-surgical Pain and Swelling
The goal of this clinical trial is to evaluate whether locally applied diclofenac sodium, with or without hyaluronidase, can reduce post-surgical pain and swelling in adult male and female patients (18 years or older) with…
- Conditions
- Root End Resection, Periapical Lesion, Single Rooted Teeth
- Trial name
- NCT07101016
- Testing
- Diclofenac Sodium Gel
- Volunteers
- 44 people
- Sponsor
- Mariam Hesham Mahmoud Abdelfattah Eissa
Dental Pain, Facial Swelling
Comparing Obturation Using Bioceramic Nano-coated Gutta-percha With Bioceramic Sealer Versus Traditional Gutta-percha With Resin Sealer for Reducing Postoperative Pain and Swelling After Root Canal Treatment in Necrotic Single-rooted Teeth.
A randomized clinical trial will compare two root canal filling approaches in necrotic single-rooted teeth. The test group will receive bioceramic mono-block obturation using bioceramic nano-coated gutta-percha with a bioceramic…
- Trial name
- NCT07600099
- Testing
- Resin sealer with conventional gutta percha., Bioceramic sealer with bioceramic gutta-percha.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spinal Cord Injuries
Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling
QUESTION. Does duroplasty improve outcome after spinal cord injury? WHAT DO WE STUDY? We will investigate whether performing a surgical procedure called duroplasty improves outcomes after spinal cord injury.
- Trial name
- DISCUS (NCT04936620)
- Testing
- Duroplasty, Spinal surgery
- Where
- 34 sites in Austria, Belgium and 10 more
- Volunteers
- 222 people
- Sponsor
- St George's, University of London
Swelling/ Edema, Trismus
The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema
This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction.
- Trial name
- NCT06953440
- Testing
- Dexamethasone Sodium Phosphate Injection
- Where
- Saudi Arabia
- Volunteers
- 66 people
- Sponsor
- King Abdulaziz University
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Erection; Incomplete
Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery
Penile erection is an unwanted event in transurethral (through the urethra) surgeries, which may be associated with adverse outcomes such as impaired access, prolonged operation time, the need to abort the operation, or the…
- Trial name
- PENIS (NCT06378645)
- Testing
- General Anesthesia: Propofol, General Anesthesia: Sevoflurane
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Etienne Xavier Keller
Spine Injury, Cord Injury, Spinal
The Outcome of Injured Cervical Spinal Cord With Uncontrolled Swelling Under Duraplasty
Overall Objective: To assess whether incorporating duraplasty alongside bony decompression enhances motor function outcomes in individuals following Traumatic Spinal Cord Injury (TSCI).
- Conditions
- Spine Injury, Cord Injury, Spinal, Cord Infarction Spinal, Incomplete Spinal Cord Injury
- Trial name
- NCT06552507
- Testing
- Duroplasty
- Where
- Taiwan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Third Molar Surgery
Intraosseous Versus Submucosal Dexamethsone Injection in Third Molar Surgery
The goal of this clinical trial is to learn if intraosseous dexamethasone injection is better for pain and swelling postop 3rd molar surgery than submucosal dexamethasone injection.
- Trial name
- NCT06720051
- Testing
- Intraosseous dexamethasone injection after 3rd molar surgery, Submucosal dexamethasone injection after 3rd molar surgery
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Knee Osteoarthritis (OA)
Clinical Study on the Combination of Xiaoyu Zhitong Formula and Lymphatic Drainage Technique to Improve the Symptoms of Knee Pain and Swelling in Cold Dampness Obstruction Type
This research project applies a combination of blood stasis relieving and pain relieving formula and lymphatic drainage technique to treat patients with cold dampness obstruction type knee joint pain.
- Trial name
- NCT06911437
- Testing
- treatment group, control group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- tang jie
Impacted Mandibular Third Molar, Postoperative Pain
Effect of Preoperative Long-Acting Corticosteroids on Pain, Swelling, and Trismus After Impacted Lower Third Molar Surgery
This study evaluated whether giving a single dose of long-acting corticosteroids before wisdom tooth surgery reduces pain, facial swelling, and limited jaw opening (trismus) after surgery.
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Facial Swelling
- Trial name
- NCT07450638
- Testing
- Dexamethasone 8 mg IM, Normal Saline IM
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al Salam University
Fluid Overload, Glomerulosclerosis, Focal Segmental
Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.
Researchers from the University of Michigan and Northwestern University are studying people's experiences with swelling caused by Nephrotic Syndrome.
- Conditions
- Fluid Overload, Glomerulosclerosis, Focal Segmental, Edema, Membranous Nephropathy
- Trial name
- Prepare-NS (NCT05505500)
- Testing
- Interview
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Michigan
Erection; Incomplete
Pornography Abstinence and Nocturnal Erections in Adult Men
The effects of pornography use on male sexual health remain uncertain, with mixed findings across existing literature and substantial variability at the individual level.
- Trial name
- NCT07618104
- Testing
- Pornography Abstinence
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Total Knee Arthroplasty Recovery
Effects of Progressive Restricted Blood Flow Exercises in Post Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM)…
- Trial name
- TKA PBFR (NCT07601906)
- Testing
- Blood Flow Restriction Exercises and Conventional Physical Therapy, Conventional Physical Therapy alone
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Pulpectomy, Irreversible Pulpitis
Clinical and Radiographic Outcomes of Rotary Instrumentation in Primary Molars
This study will evaluate the clinical and radiographic outcomes of rotary versus manual pulpectomy in children with irreversible pulpitis.A single-visit pulpectomy will be performed for all patients.
- Trial name
- NCT07319741
- Testing
- Rotary Instrumentation, Manual Instrumentation
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Anfal mohamed elmotaz almogtaba