Clinical trials: Sympathectomy
Ventricular Tachycardia
REnal SympathetiC Denervation to sUpprEss Tachyarrhythmias in ICD Recipients
The objective of this trial is to determine the efficacy and safety of adjunctive catheter-based renal sympathetic denervation (RSDN) in the primary prevention of implantable cardioverter defibrillator (ICD) therapy in patients…
- Trial name
- RESCUE (NCT01747837)
- Testing
- Boston Scientific Vessix Renal Denervation System
- Where
- 4 sites in United States, Czechia and 1 more
- Volunteers
- 48 people
- Sponsor
- Vivek Reddy
Hypertension
Safety and Efficacy Study of Renal Artery Ablation in Resistant Hypertension Patients
This is a prospective, multicenter, feasibility study on the safety and efficacy of renal denervation in patients with resistant hypertension.
- Trial name
- EnligHTN-I (NCT01438229)
- Testing
- St. Jude Medical renal artery ablation system: RF ablation generator (IBI 1500T11.5) and Renal artery ablation catheter (DS3D001, DS3D002)
- Where
- 4 sites in Australia, Greece
- Volunteers
- 47 people
- Sponsor
- Abbott Medical Devices
Hypertension Secondary to Renal Disease
Treatment of Resistant Hypertension by Renal Sympathetic Denervation in Patients Undergoing Dialysis Therapy
The study is designed to investigate the efficacy of renal nerve denervation in treating drug-resistant hypertension in patients with end stage renal disease.
- Trial name
- TreatDialRDN (NCT01881035)
- Testing
- Renal nerve denervation
- Where
- Finland
- Volunteers
- 6 people
- Sponsor
- Turku University Hospital
Hypertension, Renal
RDN Fesibility Study
Renal sympathetic denervation (RDN) was considered an effective alternative for patients whose blood pressure (BP) is not optimally controlled.
- Trial name
- NCT05743894
- Testing
- Symplicity Spyral RENAL DENERVATION (RDN) SYSTEMTM Livewire™ Reflexion™ Catheter
- Where
- 2 sites in Hong Kong
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Coronary Artery Disease, Erector Spinae Plane Block
Effects of Erector Spinae Plane Block Method Used in Pain Management in Heart Surgery on Vascular Diameters
Off-pump coronary artery bypass grafting (OPCABG) is a bypass method performed on the working heart. Pain is a frequently seen side effect experienced following this surgery.
- Conditions
- Coronary Artery Disease, Erector Spinae Plane Block, Bypass Extremity Graft
- Trial name
- NCT04447560
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Koç University
Hypertension
Effect of Renal Denervation in End Staged Renal Disease With Resistant Hypertension
A. Hypertension is a major cardiovascular risk factor and numerous treatment strategies have been developed to treat hypertension properly and reduce cardiovascular risk. B.
- Trial name
- NCT02346045
- Testing
- Renal sympathetic denervation
- Where
- 4 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul St. Mary's Hospital
Anesthesia, Local, Cerebral Vasospasm
Cervical Sympathetic Block in Patients With Cerebral Vasospasm
The purposes of this study are twofold: 1) to assess the effect of a cervical sympathetic block on cerebral blood flow in patients suffering from cerebral vasospasm, after aneurysmal subarachnoid hemorrhage; 2) to evaluate the…
- Conditions
- Anesthesia, Local, Cerebral Vasospasm, Subarachnoid Hemorrhage, Aneurysmal
- Trial name
- NCT05230134
- Testing
- Cervical sympathetic block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients
This is a Prospective, controlled, single-blind, randomized (2:1, Intervention:Control) clinical trial. The purpose of the study is to determine the role of adjunctive renal sympathetic denervation in the prevention of Atrial…
- Trial name
- NCT05988411
- Testing
- Renal Denervation, Catheter Ablation
- Where
- 8 sites in United States
- Volunteers
- 143 people
- Sponsor
- Vivek Reddy
Hypertension
Renal Sympathectomy in Treatment Resistant Essential Hypertension, a Sham Controlled Randomized Trial
The purpose of this double blind, randomized and sham controlled study is to determine whether renal denervation in terms of catheter based ablation in the renal arteries is effective in lowering blood pressure in patients with…
- Trial name
- ReSET (NCT01459900)
- Testing
- Renal artery ablation, Renal angiography
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- Aarhus University Hospital Skejby
Hypertension
Sympathetic Mapping/ Ablation of Renal Nerves Trial
To evaluate the safety and efficacy of targeted renal sympathetic denervation using SyMapCath I® and SYMPIONEER S1® Stimulator/ Generator in patients with essential hypertension for at least 6 months of the disease history and…
- Trial name
- SMART (NCT02761811)
- Testing
- SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator
- Where
- 15 sites in China
- Volunteers
- 220 people
- Sponsor
- SyMap Medical (Suzhou), Ltd.
Hyperhidrosis Primary Focal Palms
Outcome Of Bilateral Thoracoscopic Sympathectomy for Patients With Primary Focal Hyperhidrosis
The goal of this clinical trial is to examine the overall efficiency of Bilateral Thoracoscopic Sympathectomy on the permanent reduction of Primary focal hyperhidrosis of predilective parts of the body, palms, armpits, face, and…
- Trial name
- NCT06638827
- Testing
- Thoracic Sympathectomy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Uncontrolled Hypertension
Impact of Renal SympAthetic DenerVation on Chronic HypErtension
Despite the development of many drug therapies designed to treat high blood pressure (hypertension), it remains a considerable and poorly managed health, social and economic burden.
- Trial name
- SAVE (NCT01628198)
- Testing
- Celcius Thermacool Catheter or Chilli II Cooled Ablation Catheter
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Vivek Reddy
Hypertension, Atrial Fibrillation
Renal Sympathetic Denervation in Patients With Drug-resistant Hypertension and Symptomatic Atrial Fibrillation
To study whether renal sympathetic denervation(RSD) is safe and effective in patients with drug-resistant hypertension and symptomatic atrial fibrillation.
- Trial name
- RSDforAF (NCT01713270)
- Testing
- renal sympathetic denervation, drug, Direct-Current Cardioversion
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Erector Spinae Plane Block, Children
Erector Spinae Plane Block for Children Undergoing Thoracoscopic Sympathectomy
This study aims to evaluate the influence of ultrasound-guided erector spinae plane block on postoperative pain and diaphragmatic dysfunction in pediatric patients undergoing thoracoscopic sympathectomy.
- Conditions
- Erector Spinae Plane Block, Children, Thoracoscopic Sympathectomy
- Trial name
- NCT06984874
- Testing
- Erector spinae plane block, General anesthesia
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Coronary Heart Disease
Renal Sympathetic Denervation as Secondary Prevention for Patients After Percutaneous Coronary Intervention.
To study whether renal sympathetic denervation(RSD) will reduce the all-cause mortality and the recurrence rate of a composite of cardiovascular event(including angina, myocardial infarction, repeat percutaneous coronary…
- Trial name
- RSD4CHD2PRE (NCT01733901)
- Testing
- RSD, PCI
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Compensatory Hyperhidrosis, Compensatory Sweating
"Incidence of Compensatory Hyperhidrosis After T3 Vs T3-4 Sympathectomy"
The goal of this study is to compare the proportion of compensatory hyperhidrosis patients after sympathectomy at T3 level and sympathectomy at T3-4 level.
- Trial name
- NCT07196319
- Volunteers
- 46 people
- Sponsor
- Assiut University
Uncontrolled Hypertension
Renal Sympathetic Denervation for the Management of Chronic Hypertension
Despite the development of numerous drug therapies designed to treat hypertension, it remains a considerable and poorly managed health, social and economic burden.
- Trial name
- RELIEF (NCT01628172)
- Testing
- Biosense Webster Celcius Thermacool catheter
- Where
- 2 sites in Czechia
- Volunteers
- 96 people
- Sponsor
- Vivek Reddy
Treatment Resistant Essential Hypertension, Insulin Resistance
The Effects of Renal Denervation on Insulin Sensitivity
Renal sympathetic nerves contribute to development of hypertension. Sympathetic overactivity also induces insulin resistance and it could therefore be assumed that a renal denervation might improve insulin sensitivity.
- Trial name
- NCT01631370
- Testing
- Renal denervation
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Aarhus
Hypertension, Chronic Kidney Disease
Renal Sympathetic Denervation as a New Treatment for Therapy Resistant Hypertension
The aim of this study is to assess whether renal denervation (RD) added to usual care compared to usual care alone reduces blood pressure (BP) as determined with ambulatory BP monitoring (ABPM) after 6 months in subjects with an…
- Trial name
- SYMPATHY (NCT01850901)
- Testing
- Renal sympathetic denervation
- Where
- Netherlands
- Volunteers
- 139 people
- Sponsor
- UMC Utrecht
Hypertension, Renal
Transcatheter Renal Artery Sympathetic Denervation Observational Study
Hypertension is a common health problem that affects millions of people in the world. Poorly controlled blood pressure (BP) leads to cardiovascular, cerebrovascular and renal complications.
- Trial name
- NCT05744986
- Testing
- SYMPICITY Spyral RENAL DENERVATION (RDN) SYSTEMTM
- Where
- 2 sites in Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong