Clinical trials: Synkineses
Bell Palsy
Kabat Technique and Neuromuscular Effect in Patients With Bell's Palsy
Bell's palsy is the sudden one-sided peripheral weakness of seventh cranial nerve (Facial nerve), represents 50% to 75% of all etiologies with a rate of 58.2 to 8 new cases per 1 million per year.
- Trial name
- NCT04807491
- Testing
- Kabat Technique's, Neuromuscular Re-Education
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Facial Paralysis, Facial Palsy
Turkish Validation of the Synkinesis Assessment Questionnaire (SAQ)
Peripheral facial palsy may result in synkinesis, a condition characterized by involuntary facial muscle movements that occur during voluntary facial expressions.
- Conditions
- Facial Paralysis, Facial Palsy, Bell Palsy
- Trial name
- NCT07750561
- Testing
- Synkinesis Assessment Questionnaire (SAQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Barış CELBEK
Bell Palsy
Kabat Rehabilitation Versus Mime Therapy on Facial Disability and Synkinesis in Patients of Bell's Palsy
Bell's palsy, also called idiopathic facial paralysis, is a common cause of unilateral facial paralysis. It is one of the most common neurological disorders of the cranial nerves.
- Trial name
- NCT06029855
- Testing
- Kabat Therapy, Mime Therapy
- Where
- Pakistan
- Volunteers
- 85 people
- Sponsor
- University of Lahore
Peripheral Facial Palsy, Rehabilitation
Evaluation of the Effectiveness of Virtual Reality Self-rehabilitation in the Treatment of Facial Paralysis and Synkinesis
Peripheral facial palsy affects 15 to 40 people per 100,000 inhabitants and induces important functional and social repercussions.
- Conditions
- Peripheral Facial Palsy, Rehabilitation, Virtual Reality
- Trial name
- RéMiFaSy (NCT05547152)
- Testing
- massages, motor stimulation and stretching, virtual reality
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Facial Paralysis
Mindfulness in Nonflaccid Facial Paralysis
The purpose of this study is to learn more about how mindfulness techniques can help reduce anxiety, depression and body image disturbance as well as improve synkinesis in individuals with non-flaccid facial paralysis.
- Trial name
- NCT07127016
- Testing
- Mindfulness Sessions, No Mindfulness Sessions
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
Bell Palsy
Mime Therapy With and Without Neural Mobilization in Bell's Palsy.
To determine the Effects of Mime Therapy with and without Neural Mobilization on Facial symmetry, Synkinesis and Functional abilities in Patients with Bell's Palsy.
- Trial name
- NCT06459830
- Testing
- Mime Therapy with Neural Mobilization
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Synkinesis
Botox Injections in Non-Cranial Nerve VII Innervated Muscles for Facial Synkinesis
Facial synkinesis is a condition that occurs following facial nerve (CN7) injury, typically secondary to Bell's palsy, trauma, surgery (e.g., acoustic neuroma resection), or malignancy.
- Trial name
- NCT07295288
- Testing
- Botulinum Toxin Type A Injection [Botox]
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Congenital Fibrosis of Extraocular Muscles, Duane Retraction Syndrome
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies
The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.
- Conditions
- Congenital Fibrosis of Extraocular Muscles, Duane Retraction Syndrome, Duane Radial Ray Syndrome, Mobius Syndrome
- Trial name
- NCT03059420
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Blepharoptosis, Synkinesis
Oxymetazoline Drops for Acquired Blepharoptosis From Synkinesis
After an episode of facial paralysis, as nerves recover, they aberrantly regenerate and send additional branches to the incorrect muscles in addition to the intended muscle.
- Conditions
- Blepharoptosis, Synkinesis, Hyperkinesis, Facial Paralysis
- Trial name
- NCT05945615
- Testing
- Oxymetazoline 0.1% (Pf) Oph Soln Ud, Preservative free lubricating drops
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Facial Paralysis, Sinkynesis
Eye Soft Surgery for Facial Sinkynesis
Facial synkinesis (FS) is a distressing sequela of facial palsy (FP) characterized by involuntary, simultaneous movements of facial muscles occurring during voluntary facial expressions.
- Trial name
- NCT06538103
- Testing
- Eye soft surgery, Physical Rehabilitation
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Catania
Synkinesis
Mixed Methods Investigation of Chronic Facial Paralysis in Individuals With Synkinesis
This proposal will prospectively assess the social, physical, and emotional recognition function in participants with synkinesis.
- Trial name
- NCT04148872
- Testing
- Neuromuscular Retraining Therapy (4 months), Chemodenervation (4 months), Neuromuscular Retraining + Chemodenervation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Peripheral Facial Paralysis, Facial Palsy
Functional Recovery From Facial Paralysis
This is a controlled, single-blind (hybrid) clinical investigation that aims to analyze the process of recovery of muscle function in people with peripheral facial paralysis who receive kinesthetic treatment with…
- Conditions
- Peripheral Facial Paralysis, Facial Palsy, Synkineses
- Trial name
- NCT06532903
- Testing
- Selective muscle electrostimulation with exponential current, Facial muscle reeducation in front of the mirror
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- Universidad Nacional del Nordeste, Argentina
Facial Nerve Injuries, Facial Paresis Associated With Facial Nerve Dysfunction
Comparison of Three Botulinum Neuromodulators for Management of Facial Synkinesis
The purpose of this study is to compare the effectiveness of three commercially available botulinum toxin neuromodulators in the treatment of facial synkinesis using patient reported outcome measures.
- Conditions
- Facial Nerve Injuries, Facial Paresis Associated With Facial Nerve Dysfunction, Facial Asymmetry, Synkinesis
- Trial name
- NCT03048383
- Testing
- OnabotulinumtoxinA Injectable Product, AbobotulinumtoxinA Injectable Product, Incobotulinumtoxin A Injectable Product
- Volunteers
- 71 people
- Sponsor
- University of Utah
Bell's Palsy
Low Laser Therapy on Facial Motor Functions Function and Synkinesis in Patients With Bell's Palsy
To determine the effects of low-level laser therapy on facial motor functions and synkinesis in patients with bell's palsy
- Trial name
- NCT05707091
- Testing
- Low level laser therapy and conventional therapy, Conventional therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Facial Synkinesis
Functional MRI Study Facial Synkinesis
Rationale. Facial synkinesis is one of the most common consequences after facial paralysis, defined as the inability to move muscles due to nerve damage.
- Trial name
- NCT05121896
- Testing
- MRI Scan
- Where
- Netherlands
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Synkinesis, Facial Nerve Palsy
Efficacy of Topical Apraclonidine for the Treatment of Ocular Synkinesis
The purpose of this study is to determine efficacy of apraclonidine for patients with ocular synkinesis, who are seen in the UAB Facial Nerve Clinic.
- Trial name
- NCT05167760
- Testing
- Apraclonidine
- Sponsor
- University of Alabama at Birmingham
Facial Paralysis, Facial Palsy
Neurotomy to Treat Synkinesis Following Peripheral Facial Palsy
The purpose of this study is to evaluate neurotomy as an alternative treatment to Botox injections for severe synkinesis following peripheral facial palsy
- Conditions
- Facial Paralysis, Facial Palsy, Peripheral Facial Palsy, Peripheral Facial Paralysis
- Trial name
- NCT05191719
- Testing
- Botox injection, Neurotomy
- Where
- Sweden
- Volunteers
- 73 people
- Sponsor
- Rebecka Ohm
Bell Palsy
Motor Imagery and Mirror Therapy on Synkinesis, Facial Asymmetry, Facial Function and QoF in Bell's Palsy Patients.
Bell's palsy is a condition that causes sudden weakness in the muscles on one side of the face. The weakness makes half of the face appear to droop, difficulty in closing eyes and synkinesis.
- Trial name
- NCT06775717
- Testing
- Motor Imagery with conventional Treatment, Mirror therapy with conventional Treatment.
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University