Clinical trials: System; Sclerosis
Multiple Sclerosis
Description of Adherence to the Main Preventive Health Campaigns of Persons With Multiple Sclerosis
Persons with multiple sclerosis (PwMS) might be more susceptible to infections and cancers and chronic diseases than general population, not because of the presence of the disease itself, but in relation to some specific…
- Trial name
- preventionMS (NCT04930380)
- Testing
- phone interview
- Where
- 12 sites in Italy
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- University of Siena
Parkinson, Multiple Sclerosis
Driving Performance in Parkinson's Disease and Multiple Sclerosis Using a Driving Simulator
This prospective observational study investigates whether driving performance measured in a standardized driving simulator differs between people with Parkinson's disease, people with multiple sclerosis, and healthy drivers.
- Trial name
- NeuroSimDrive (NCT07809828)
- Testing
- Standardized Driving Simulator Assessment
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Olomouc
Ehlers-Danlos Syndrome, Multiple Sclerosis
Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI)
The investigators propose that evidence of chronic cerebrospinal venous insufficiency (CCSVI) may be evident in the vasculature of the fundus.
- Trial name
- NCT01356134
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Genetic Disease Investigators
Amyotrophic Lateral Sclerosis
Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron Disorders
The purpose of this study is to collect, from patients with sporadic and familial ALS and their family members, clinical data and blood samples for extraction of DNA, RNA, preparation of lymphocytes, plasma and serum to establish…
- Trial name
- NCT05474235
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Multiple Sclerosis
The Minnesota Manual Dexterity Test As A Measure Of Hand Function in Multiple Sclerosis
The aim of the study is to report the results of manual dexterity using the Minnesota Manual Dexterity Test in people with Multiple Sclerosis.
- Trial name
- NCT04721340
- Testing
- Test Group, Control Grup
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Virtual Peer-to-peer Support Programme for Carers of MND
Background/scope There is growing recognition that family caregiving is a serious public health issue requiring supportive interventions.
- Trial name
- NCT04695210
- Testing
- Virtual peer-to-peer support
- Where
- 25 sites in United Kingdom
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- King's College London
Multiple Sclerosis
Transcranial Doppler in Multiple Sclerosis
The aim of this study is to investigate the potential of Transcranial doppler (TCD) and Near-Infrared Spectroscopy (NIRS), more simple and non-invasive bedside methods than magnetic resonance imaging (MRI), to evaluate changes in…
- Trial name
- TRADOMS (NCT02389426)
- Testing
- TCD baseline, TCD after bosentan administration, NIRS baseline
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Fatigue
Effect of Melatonin on Multiple Sclerosis Related Fatigue
The purpose of this study was to evaluate the efficacy and safety of Melatonin in treatment of fatigue and Quality of Life of MS patients.
- Trial name
- NCT01718678
- Testing
- Melatonin
- Where
- Iran
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Multiple Sclerosis, Rehabilitation
Robot-assisted Arm Training in Multiple Sclerosis
The upper limb (UL) plays an important role in the daily functioning of patients with Multiple Sclerosis (MS) and negatively influences their quality of life. Effective arm-hand training programs are needed.
- Trial name
- RAMSES (NCT03561155)
- Testing
- Robot assisted treatment (Amadeo®), Conventional treatment
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Multiple Sclerosis
Wrist Position Sense in Individuals With Multiple Sclerosis
No study has been found examining the effect of wrist position sense on manual dexterity in individuals with multiple sclerosis.The purpose of this study is to examine the effect of wrist position sense on manual dexterity of the…
- Trial name
- NCT06232850
- Testing
- Position sense and manual dexterity evaluate
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Relapsing Remitting Multiple Sclerosis
Tolerability of Acthar for the Treatment of Multiple Sclerosis in Relapses (TAMS)
Tolerability of Acthar for the Treatment of Multiple Sclerosis Relapses (TAMS)
- Trial name
- NCT02258217
- Testing
- Acthar
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- OhioHealth
Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Primary Progressive
Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients
Different therapies can improve clinical and motor symptoms of multiple sclerosis (MS) similarly, but studies comparing the effects of different exercise therapies on clinical and motor outcomes are scant.
- Trial name
- NCT04550650
- Testing
- Training groupe, PNF, Spinning grp
- Where
- Hungary
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Multiple Sclerosis
Correlation Between PET and Advanced MRI in Multiple Sclerosis
Traditional Magnetic Resonance Imaging (MRI) in Multiple Sclerosis (MS) has enabled clinicians to measure disease activity but there are inherent limitations.
- Trial name
- NCT02869360
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
ALS, ALS (Amyotrophic Lateral Sclerosis)
Systems Biology of Amyotrophic Lateral Sclerosis (ALS)
The goal of this observational study is to identify molecular features in multiple clinical samples and/or the patient environment that are associated with ALS.
- Trial name
- NCT07007390
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Viome
Systemic Sclerosis, Scleroderma
Effects of Probiotics on Gastrointestinal Symptoms and on the Immune System in Patients With Systemic Sclerosis
Systemic sclerosis (SSc) is an autoimmune disease with unknown etiology, which affects especially the gastrointestinal tract, lungs, heart and kidneys.
- Trial name
- SSc (NCT02302352)
- Testing
- Probiotic
- Where
- Brazil
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Sclerosis, Multiple
Exploration of Microcirculatory Alteration and Endothelial Dysfunction by Adaptive Optics in Multiple Sclerosis
It's a pilot, interventional prospective monocentric study. It aims to compare the wall / lumen ratio (WLR) of retinal arterioles (common marker of microangiopathies) between patients with multiple sclerosis and controls using…
- Trial name
- MS-EYE (NCT03508089)
- Testing
- Ocular fundus on patient with Multiple Sclerosis, Ocular Fundus on voluntary person
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Versailles Hospital
Alzheimer's Disease, Parkinson's Disease
Rajavtihi Neuronal Adult Stem Cells Project
To study the success of Oligodendrocyte progenitor cell culture project in Rajavithi Hospital to identify an unlimited clone human neuronal progenitor stem cells from the human brain in the Biomolecular Research Center.
- Conditions
- Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis
- Trial name
- RNASc (NCT00927108)
- Testing
- Progenitor Stem Cell Culture
- Where
- Thailand
- Volunteers
- healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Systemic Sclerosis (SSc), Diffuse Cutaneous Systemic Sclerosis
TL1A Inhibition in Systemic Sclerosis-Related Skin Fibrosis and Immunological Alterations: A Proof-of-Concept In Vitro Study (FIBROSTOP)
Systemic Sclerosis (SSc) is a rare autoimmune connective tissue disease characterized by microvascular injury, immune activation, and progressive fibrosis of the skin and internal organs.
- Conditions
- Systemic Sclerosis (SSc), Diffuse Cutaneous Systemic Sclerosis, Skin Fibrosis
- Trial name
- FIBROSTOP (NCT07642297)
- Testing
- TL1A stimulation and inhibition (in vitro)
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Multiple Sclerosis
Digital Gait Analysis in the Home Environment of Patients With Multiple Sclerosis
The aim of this study is the development of novel telemedical examination methods based on sensor-based gait analysis in patients with multiple sclerosis (MS).
- Trial name
- MSgoesHome (NCT04771858)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical Valley Digital Health Application Center GmbH
Multiple Sclerosis
Applications of Nanotechnology in Multiple Sclerosis by Respiratory Samples
Multiple Sclerosis (MS) is a complex multi-factorial disease, with underlying both genetic and environmental factors. Different populations have different susceptibility.
- Trial name
- MS-NANOSE (NCT01206023)
- Testing
- NA-NOSE artificial olfactory system
- Where
- 2 sites in Israel
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center