Clinical trials: System Sclerosis
Sclerosis, Multiple
Exploration of Microcirculatory Alteration and Endothelial Dysfunction by Adaptive Optics in Multiple Sclerosis
It's a pilot, interventional prospective monocentric study. It aims to compare the wall / lumen ratio (WLR) of retinal arterioles (common marker of microangiopathies) between patients with multiple sclerosis and controls using…
- Trial name
- MS-EYE (NCT03508089)
- Testing
- Ocular fundus on patient with Multiple Sclerosis, Ocular Fundus on voluntary person
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Versailles Hospital
Multiple Sclerosis, Inflammatory Disease
Remyelination in Multiple Sclerosis: a PET-MR Longitudinal Study Investigating Individual Profiles of Myelin Repair and the Contribution of Neuroinflammation
Multiple Sclerosis (MS) is an inflammatory disease where the immune cells invade the central nervous system and destroy an essential element of nerve conduction: the myelin.
- Trial name
- SMARTinMS (NCT05147532)
- Testing
- PET-MRI with [18F]-Florbetaben and PET-MRI with [18F]-DPA-714
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
Motor Asymmetry in Progressive Multiple Sclerosis Patients
Project Rational A better understanding of the causes of physical disability is an important unmet need in progressive Multiple Sclerosis patients.
- Trial name
- MAP-MS (NCT04918225)
- Testing
- Magnetic Resonance Imaging, Neurological examination, Multiple Sclerosis Functional Composite
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Amyotrophic Lateral Sclerosis
Involvement of Lymphocyte Type B in Amyotrophic Lateral Sclerosis (ALS)
The involvement of Lymphocyte type B in Amyotrophic lateral sclerosis (ALS) patients will be compared to lymphocyte in healthy subjects.
- Trial name
- NCT00846560
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus