Clinical trials: TOTAL ABDOMINAL HYSTERECTOMY
Hysterectomy
Randomized Controlled Trial Comparing Postoperative Pain Following TAH With GA vs. Combined GA + SAB
The investigators hypothesize that a spinal anesthetic administered prior to the induction of general anesthesia will result in reduced need for pain medication and reduced postoperative pain, as well as reduced hospital stay…
- Trial name
- NCT01511627
- Testing
- General Anesthesia + Spinal anesthesia combined, General Anesthesia (control group)
- Where
- Canada
- Sponsor
- University of Saskatchewan
Ultrasound, Rectus Sheath Block
Ultrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal Hysterectomy
This study aims to compare the effectiveness and safety of ultrasound-guided rectus sheath block versus intrathecal morphine for postoperative analgesia in patients undergoing open total abdominal hysterectomy.
- Conditions
- Ultrasound, Rectus Sheath Block, Intrathecal Morphine, Postoperative Analgesia
- Trial name
- NCT06837506
- Testing
- Rectus sheath block, Intrathecal morphine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Post Operative Pain
Ultrasound Guided Erector Spinae Plane Block vs Intrathecal Morphine
Total abdominal hysterectomy (TAH) is a major surgical procedure after which significant post-operative pain and discomfort are anticipated.
- Trial name
- NCT05218733
- Testing
- Ultrasound Guided Erector Spinae Plane Block, Intra thecal morphine., General anesthesia using intravenous fentanyl (1µgm/kg)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Hysterectomy
Preoperative Misoprostol in Reducing Blood Loss in Total Abdominal Hysterectomy (TAH)
Total abdominal hysterectomy is known to be associated with operative blood loss, which can lead to patients' morbidity. Misoprostol, a prostaglandin, has been shown to be effective in reducing operative blood loss during…
- Trial name
- NCT01199159
- Testing
- Misoprostol, Vitamin B 6
- Where
- Hong Kong
- Volunteers
- 77 people
- Sponsor
- The University of Hong Kong
Pain
Analgesic Effect of Pregabalin in Patients Undergoing Total Abdominal Hysterectomy
Pregabalin will decrease the total amount of opioid required in patients undergoing total abdominal hysterectomy. In addition, pregabalin will decrease the incidence of opioid-related side effects in patients undergoing total…
- Trial name
- NCT01466101
- Testing
- Pregabalin administration
- Sponsor
- Northwestern University
Postoperative Pain
Bilateral Erector Spinal Plan Block in Postoperative Analgesia After Total Abdominal Hysterectomy
The importance of effective postoperative pain management is well known. Overall, for total abdominal hysterectomy operations are related with severe postoperative pain.
- Trial name
- NCT05513196
- Testing
- Erector spinae plane block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Kocaeli University
Pain, Chronic, Pain, Postoperative
Efficacy of Pain Neuroscience Education and Pre-anesthetic Assessment in Reducing Levels of Anxiety, Stress and Pain in Patients Undergoing Elective Total Abdominal Hysterectomy (ENAH Study)
Through this quantitative, multivariate factorial experimental parallel randomized clinical trial, the investigators analyzed the effectiveness of pre-anesthetic assessment and pain neuroscience education in reducing anxiety…
- Conditions
- Pain, Chronic, Pain, Postoperative, Anesthesia, Surgery
- Trial name
- NCT05435508
- Testing
- Pain Neuroscience Education, Usual care
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Instituto Neurociencia Del Dolor
Pain, Postoperative
Preemptive Analgesia With Amitryptyline for Prevention of Pain in Women After Hysterectomy
The purpose of this study is to determine whether amitryptyline is effective in the prevention of pain in women after a total abdominal hysterectomy.
- Trial name
- NCT03587025
- Testing
- Amitriptyline
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Campinas, Brazil
Post Operative Analgesia
Comparative Study Between Ultrasound Guided Paravertebral Plane Block and Erector Spinae Plane Block on Post-operative Analgesia After Total Abdominal Hysterectomy
The intent of this study is to compare the efficacy of the erector spinae plane block (ESPB) and paravertebral plane block in reducing postoperative opioid consumption and pain in patients with total abdominal hysterectomy.
- Trial name
- NCT07610070
- Testing
- Paravertebral Plane Block, Erector Spinea Plane Block, bupivicaine 0.25%
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Postoperative Pain, Abdominal Hysterectomy
Effect of Different Volumes of Erector Spinae Plane Block on Postoperative Opioid Consumption After Total Abdominal Hysterectomy
his study aims to investigate the effects of different volumes of ultrasound-guided erector spinae plane block (ESPB) on postoperative pain and opioid consumption in patients undergoing total abdominal hysterectomy.
- Conditions
- Postoperative Pain, Abdominal Hysterectomy, Pain
- Trial name
- NCT07533760
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Şule Arıcan
Transversalis Fascia Plane Block, Intrathecal Morphine
Transversalis Fascia Plane Block Versus Intrathecal Morphine for Postoperative Analgesia in Total Abdominal Hysterectomy
This study aims to compare the ultrasound-guided transversalis fascia plane (TFP) block and intrathecal morphine for postoperative analgesia in patients undergoing total abdominal hysterectomy (TAH).
- Conditions
- Transversalis Fascia Plane Block, Intrathecal Morphine, Postoperative Analgesia, Total Abdominal Hysterectomy
- Trial name
- NCT07201272
- Testing
- Transversalis fascia plane block, Morphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Anesthesia,General, Cardiac Event
Hemodynamic Parameters and Cardiac Enzyme Levels in Patients Undergoing General Anesthesia
The goal of this observational study is to learn about the effects of total intravenous general anesthesia with target controlled infusion and sevoflurane based balanced general anesthesia on hemodynamic parameters and cardiac…
- Trial name
- NCT05598567
- Testing
- target controlled infusion - total intravenous general anesthesia, sevoflurane based balanced general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duzce University
Postoperative Pain
ESP vs QL for Total Abdominal Hysterectomy
Patients undergoing open total abdominal hysterectomy (n=82) at Parkland Memorial Hospital will be randomized into one of two groups to receive either ultrasound-guided bilateral ESP block with liposomal bupivacaine (Group 1) or…
- Trial name
- NCT04074226
- Testing
- Erector Spinae Plane block, Quadratus Lumborum Block
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Gynecological Surgeries
A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries(SPiM-RWS-GYN)
Study name：A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries Study purpose：This clinical trial is a real-world study to evaluate the clinical…
- Trial name
- NCT06082011
- Testing
- da Vinci SP Surgical System
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Ruijin Hospital
Abdominal Hysterectomy, Postoperative Pain
Effect of TAP Block on Stress Hormones
Random allocation of patients in two groups; Tap block group (T group) and control group (C group). All patients will receive standard general anesthesia and postoperative pain management.
- Trial name
- NCT03443271
- Testing
- TAP Block with Bupivicaine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Hysterectomy
A Prospective Randomized Control Trial Comparing Immediate and 24-hours Delayed Catheter Removal Following Hysterectomy
Total abdominal hysterectomy is a common gynaecological operation performed worldwide. In Hong Kong, it was the most common gynaecological open procedure done and the number of hysterectomies performed increased by almost 50% in…
- Trial name
- NCT01182714
- Testing
- immediate removal of in-dwelling catheter, 24 hours delayed removal of catheter
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- The University of Hong Kong
Benign Uterine Disease
Total Versus Subtotal Abdominal Hysterectomy
319 Women undergoing hysterectomy for benign (not cancer) indications were randomly allocated to 2 types of surgery (Total (TAH) and Subtotal (SAH)) abdominal hysterectomy 15 years ago.
- Trial name
- NCT01880710
- Testing
- Subtotal hysterectomy, Total Hysterectomy
- Where
- Denmark
- Volunteers
- 319 people
- Sponsor
- Nykøbing Falster County Hospital
Abnormal Uterine Bleeding, Uterine Bleeding
Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy
The purpose of the study is to investigate differences in perioperative and postoperative outcomes between the abdominal (AM) versus vaginal (VM) routes of contained morcellation in participants undergoing laparoscopic total…
- Conditions
- Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
- Trial name
- NCT04434066
- Testing
- Total Laparoscopic Hysterectomy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Pain
TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management
In this randomized, controlled, observer-blinded study we plan to evaluate pain relief after ultrasound-guided transversus abdominis plane (TAP) block using bupivacaine and wound infiltration using liposomal bupivacaine in…
- Trial name
- NCT02074709
- Testing
- Plain bupivacaine, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Analgesia
Epidural Versus Continuous Wound Ropivacaine Infusion Analgesia
Study Hypothesis: The analgesic requirements and pain scores postoperatively differ between the epidural and continuous wound infusion techniques.
- Trial name
- NCT01916473
- Testing
- Epidural analgesia, Continuous wound infusion
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- University of Athens