Clinical trials: Tailored Condition
Vitiligo
5-fluorouracil for Treatment of Stable Vitiligo
Vitiligo, a significant dermatologic challenge affecting 0.5 to 2% of the global population. Despite various existing medical approaches, current vitiligo treatments are still far from optimal.
- Trial name
- NCT06209138
- Testing
- 5 fluorouracil, Saline
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Metastatic Breast Cancer
Optimizing Quality of Life in Women Living With Metastatic Breast Cancer
The purpose of this study is to develop and tailor an intervention program to improve the quality of life in women living with metastatic breast cancer.
- Trial name
- NCT04374825
- Testing
- Acceptance and Commitment Therapy (ACT), Cognitive Behavioral Stress Management (CBSM)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Northwestern University
Breast Cancer
Effect of a Tailored Program of Physical Activity and Nutritional Counseling on Fatigue Reduction in Breast Cancer Patients Receiving an Adjuvant Treatment
Cancer-related fatigue is by far the most common symptom affecting cancer patients. Combining regular dietary counseling and tailored physical activity is associated with reduced cancer-related fatigue and can improve quality of…
- Trial name
- APAD (NCT01495650)
- Testing
- Tailored program of PA and nutritional counseling
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Breast Cancer
The Breast Cancer Online Rehabilitation Program
The investigators have developed an online rehabilitation platform to guide women in their home-based upper-body exercises after breast cancer surgery.
- Trial name
- BRECOR (NCT02673918)
- Testing
- Home-based upper-body rehabilitation with online support
- Where
- 6 sites in Denmark
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
HIV/AIDS
Hybrid STTR Intervention for Heterosexuals: Anonymous Testing and Confidential Care Linkage
The Brooklyn Community United (BCU) study is a supplement to the main research study titled "Peer Driven Intervention to Seek, Test, \& Treat Heterosexuals at High Risk for HIV." The main study's field name is Brooklyn Community…
- Trial name
- BCU (NCT02421159)
- Testing
- Seek and Test Phase, Treat and Retain Phase
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- New York University
Hypertension
Individually Tailored Web-Based Program to Improve Blood Pressure Control
High blood pressure affects 65 million adults in the United States, and more than one third of these individuals do not have adequate control of their blood pressure.
- Trial name
- NCT00377208
- Testing
- Web-Based Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Cervical Cancer, Papilloma Viral Infection
Reducing Urban Cervical Cancer Disparities
This study uses a hybrid Type 1 effectiveness-implementation trial to operationalize and assess the efficacy of the Health Enhancement Resource System (HERS) intervention.
- Trial name
- NCT06416150
- Testing
- Stage 1 SOC, Stage 1 HERS, Stage 2 HERS
- Where
- 3 sites in United States
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Pulmonary Embolism
D-dimer Testing Tailored to Clinical Pretest Probability in Suspected Pulmonary Embolism
Prospective, multicentre, cohort study assessing a diagnostic management strategy for suspected Pulmonary Embolism with independent central adjudication of outcomes
- Trial name
- PEGeD (NCT02483442)
- Where
- 9 sites in Canada
- Volunteers
- 2,038 people
- Sponsor
- McMaster University
Diabetes
Nxstan: A Culturally Tailored Intervention to Prevent Diabetes in American Indian Men
To reduce modifiable diabetes risk factors' in overweight and obese AI men residing on the Colville reservation through a community-based, culturally informed intervention, the study specifically aims to: 1.
- Trial name
- NARCH (NCT02952352)
- Testing
- Diabetes Prevention Program
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Washington State University
Hypertension
Tailored Messaging to Reduce Sodium Intake
The proposed study will determine the effectiveness of a mobile application location-based tailored notification message system in helping hypertensive patients reduce dietary sodium intake and feel more confident in following a…
- Trial name
- NCT03099343
- Testing
- Location-based Tailored Messaging
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Metastatic Colorectal Cancers, Metastatic Gastric Cancers
Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers
Prospective non randomized, non-comparative, dose escalation, two arms open phase I trial to assess the safety and tolerability of capecitabine given in combination with aflibercept in patients with measurable or evaluable…
- Conditions
- Metastatic Colorectal Cancers, Metastatic Gastric Cancers, Metastatic Oesophageal Cancers, Metastatic Pancreatic Cancers
- Trial name
- MOMENTUM1 (NCT01843725)
- Testing
- capecitabine, aflibercept
- Where
- Belgium
- Volunteers
- 37 people
- Sponsor
- Jules Bordet Institute
Diet, Healthy, HbA1c
Medically Tailored Meals for Cardiovascular Health
This randomized clinical trial (RCT) will investigate novel approaches to enhance effectiveness, engagement, reach, and cost-effectiveness of medically tailored meals (MTM) programs for promoting cardiovascular health, focusing…
- Conditions
- Diet, Healthy, HbA1c, Blood Pressure
- Trial name
- MTM4CVH (NCT06550297)
- Testing
- Medically Tailored Meals and Nutritional Counseling, Cardiovascular Health Promotion Educational Program
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Columbia University
Neurofibromatosis 1
Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy
This decentralized, randomized study seeks to assess the feasibility, acceptability, and preliminary effectiveness of two approaches to assisting Neurofibromatosis 1 (NF1) patients with low health literacy improve their…
- Trial name
- NCT07233408
- Testing
- NF1 Educational Videos, Peer Navigator, Letters about NF1 Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Hodgkin Lymphoma, Non-hodgkin Lymphoma
Improving Exercise Capacity With Tailored Physical Activity in Lymphoma & Breast Cancer Patients Undergoing Tx
To provide critical participant enrollment data necessary to complete a larger definitive clinical trial in the future.
- Conditions
- Hodgkin Lymphoma, Non-hodgkin Lymphoma, Lymphoma, Breast Cancer
- Trial name
- NCT03923504
- Testing
- Physical Activity Intervention (PAI), Healthy Living Control
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Virginia Commonwealth University
Atrial Fibrillation
The Ablate-by-LAW Study
Of all the determinants of lesion creation during atrial fibrillation (AF) ablation, left atrial wall thickness (LAWT), as measured with multi-detector cardiac tomography (MDCT) is one key element that has been evaluated in some…
- Trial name
- NCT04218604
- Testing
- Personalized atrial fibrillation ablation
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 106 people
- Sponsor
- Centro Medico Teknon
Childhood Vaccinations
Tailoring of Vaccine-Focused Messages: Moral Foundations
This study is the first phase of a trial examining decision making about vaccines. This phase tests the impact of targeted vaccine-focused health messages on vaccine beliefs held by parents of young children and pre-adolescents.
- Trial name
- NCT02851459
- Testing
- Baseline Survey, Pre-intervention Survey, Morally Congruent Message
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Emory University
Pelvic Organ Prolapse
Comparisons of Clinical Outcomes Between Novel Tailored Transvaginal Mesh Surgery and Vaginal Native Tissue Repair Surgery for Pelvic Organ Prolapse
The issue of whether utilizing the mesh in the surgical treatment of pelvic organ prolapse remained undetermined.Thus, the aim of this study is to analyze clinical outcome of women who underwent pelvic organ prolapse surgeries…
- Trial name
- NCT02465710
- Testing
- Pelvic organ prolapse surgery without mesh, Pelvic organ prolapse surgery with mesh
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Healthcare Disparities, Minority Health
Tailored Approach to Sleep Health Education: A Community Engaged Approach
This study aims to develop educational tools and platforms to promote the transfer of sleep health information to blacks to foster adoption of healthful sleep practices.
- Conditions
- Healthcare Disparities, Minority Health, Sleep, Sleep Disorders
- Trial name
- TASHE (NCT02507089)
- Testing
- Tailored sleep health education materials., Generic sleep health education materials.
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Ventral Hernia, Umbilical Hernia
Prospective Study Of A Size Tailored Approach To Repair Umbilical And Epigastric Primary Ventral Hernias
Primary ventral hernias, such as umbilical and epigastric hernias, are best repaired with abdominal wall reinforcement by mesh implantation.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia
- Trial name
- SITUP (NCT01639118)
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Nicotine Dependence, Tobacco Use
Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers
The project is designed to examine the effectiveness of strategies to increase access to treatment for tobacco use and dependence among rural Veteran smokers.
- Trial name
- NCT01892813
- Testing
- Nicotine replacement therapy - Transdermal nicotine patch, Nicotine replacement therapy - Nicotine gum, Nicotine replacement therapy - Nicotine lozenge
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Mark Vander Weg