Clinical trials: Tailored Condition
Acute Coronary Syndrome
Half Dose of Prasugrel and Ticagrelor in Acute Coronary Syndrome (HOPE-TAILOR)
East Asian patients will be required optimal dose of newer P2Y12 inhibitors (prasugrel or ticagrelor) to determine the safer treatment and better outcome.
- Trial name
- NCT02944123
- Testing
- Clopidogrel 75 mg, Prasugrel 5 mg, Ticagrelor 45 mg
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Dong-A University
Malaria
Malaria High-Risk Populations in Namibia
This study aims to determine the effectiveness, cost-effectiveness, acceptability, and feasibility of targeted delivery of a package of malaria interventions for improving effective coverage and reducing Plasmodium falciparum…
- Trial name
- NCT04094727
- Testing
- Presumptive treatment with Artemether-lumefantrine (AL), Enhanced vector control
- Where
- Namibia
- Volunteers
- 3,302 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Inflammatory Bowel Diseases
Tailored Therapeutic Model According to the Expression of Genes in Inflammatory Bowel Disease Patients
This study is a randomized controlled study conducted at five tertiary university hospitals. Patients who are 20-80 years old, diagnosed as having Inflammatory Bowel Disease(IBD) and who are planned to start thiopurines for the…
- Trial name
- NCT03719118
- Testing
- genotyping for three genes (TPMT, NUDT15 and FTO), non-genotyping
- Where
- 5 sites in South Korea
- Volunteers
- 215 people
- Sponsor
- Yonsei University
Chronic Pain, Depressive Symptoms
Internet-delivered Cognitive Behavioral Therapy for Patients With Chronic Pain and Psychiatric Distress
This study is a randomized controlled trial studying the efficacy of an iCBT treatment for patients with chronic pain and comorbid psychiatric distress.
- Conditions
- Chronic Pain, Depressive Symptoms, Anxiety, Stress, Psychological
- Trial name
- TIPPS (NCT03316846)
- Testing
- Internet-Delivered Cognitive Behavioral Therapy
- Where
- Sweden
- Volunteers
- 187 people
- Sponsor
- Uppsala University
Cancer-related Fatigue
The Efficacy of Health Navigation® for Cancer-Related Fatigue in Cancer Survivors
The objective of this study is 1. to develop a web-based, tailored program for Cancer-related fatigue in cancer survivors, which is comprehensive and evidence-based, 2.
- Trial name
- NCT01228773
- Testing
- Tailored web-based care program (Health Navigation®)
- Where
- South Korea
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Fatigue, Depression
Health Literacy Assessment and Intervention to Reduce Disparities: FLIGHT/VIDAS II
The purpose of this study will to be to evaluate the effects of a mobile intervention focused on improving the chronic disease self management skills of individuals with low health literacy.
- Conditions
- Fatigue, Depression, Pain, Sleep Wake Disorders
- Trial name
- FV2 (NCT02922439)
- Testing
- Tailored Intervention, Control Intervention
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Hodgkin Lymphoma
Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Favorable-Risk Hodgkin Lymphoma
This phase II trial is studying how well combination chemotherapy with or without radiation therapy works in treating young patients with favorable-risk Hodgkin lymphoma.
- Trial name
- NCT00846742
- Testing
- Stanford V Chemotherapy, Radiation Therapy
- Where
- 6 sites in United States
- Volunteers
- 88 people
- Sponsor
- St. Jude Children's Research Hospital
Life Stress, Smoking Cessation
Promoting Health During Pregnancy: A Multiple Behavior Computer Tailored Intervention
This program of research tested the effectiveness of an iPad delivered multiple behavior intervention grounded in the Transtheoretical Model of Behavior Change for pregnant women.
- Conditions
- Life Stress, Smoking Cessation, Poor Nutrition
- Trial name
- NCT01997151
- Testing
- Healthy Pregnancy: Step by Step
- Volunteers
- 374 people
- Sponsor
- Pro-Change Behavior Systems
Obstructive Sleep Apnea
Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation Workers
The objective of this protocol is to conduct a focus group to identify OSA beliefs, attitudes, and knowledge among employees in the transportation industry on shift schedules.
- Trial name
- NCT05039528
- Testing
- Personalized OSA messages, Control
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Dental Caries
Evaluation of a Brief Tailored Motivational Intervention to Prevent Early Childhood Caries
The Detroit Dental Health Project (DDHP)aims to promote oral health and reduce disparities within the community of low-income African-American children (0-5 years) and their main caregivers (14+ years), living in the City of…
- Trial name
- NCT01123330
- Testing
- Motivational Interviewing
- Where
- United States
- Volunteers
- 2,042 people, healthy volunteers welcome
- Sponsor
- Temple University
Analgesia, Patient-Controlled
Tailored PCA Based on Preoperative Pain Sensitivity
Opioids via intravenous patient-controlled analgesia (IV PCA) are widely used for postoperative pain control. However, effective pain control with minimized side effects of analgesic agents is still challenging.
- Trial name
- NCT03252977
- Testing
- Tailored regimen of IV PCA according to pain sensitivity, Regimen of IV PCA without considering pain sensitivity
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Seoul National University Hospital
Migraine With Aura, Migraine Without Aura
Tailored Digital Treatment for Migraine
Background: An individualized internet-based treatment program from a biopsychosocial perspective has been developed within the Västra Götaland region (VGR) with funds from the Innovation Fund.
- Trial name
- NCT05617339
- Testing
- I am (internet approach to migraine)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Suspected Deep Vein Thrombosis
The Designer D-dimer Deep Vein Thrombosis Diagnosis (4D) Study
This is a cohort study that will assess a new diagnostic management strategy for suspected Deep Vein Thrombosis in outpatients.The new diagnostic strategy is designed to reduce the use of ultrasound testing on the day of…
- Trial name
- 4D (NCT02038530)
- Where
- 10 sites in Canada
- Volunteers
- 1,513 people
- Sponsor
- McMaster University
Major Depressive Disorder, Schizophrenia
Disorder-tailored Transcranial Direct Current Stimulation (tDCS) of the Prefrontal Cortex
Major depressive disorder (MDD) is a common, recurrent, and frequent chronic disorder. Among others, deficient cognitive control over emotional distraction is a central characteristic of MDD (Ochsner \& Gross 2005; Disner et al.
- Trial name
- MRSDC1 (NCT02715128)
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Sepsis
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis
Little is known about the optimal fluid therapy of patients with uncomplicated sepsis. Most recommendations are extrapolated from studies performed in patients with septic shock.
- Trial name
- NCT03728998
- Testing
- Passive leg raise (PLR), Clearsight non-invasive hemodynamic monitoring system
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Frisius Medisch Centrum
Myocardial Infarction, Aging
Physical Activity Intervention in ELderly Patients With Myocardial INfarction
Elderly patients presenting with myocardial infarction (MI) are the highest risk population with the worst prognosis. No trial has ever been designed to optimize their outcome through a systematic improvement of their physical…
- Trial name
- PIpELINe (NCT04183465)
- Testing
- Health Education, Multi-domain lifestyle intervention
- Where
- 7 sites in Italy
- Volunteers
- 512 people
- Sponsor
- University Hospital of Ferrara
Heart Failure
A Trial to Evaluate Medically Tailored Meals With Patients With Heart Failure
The goal is to conduct a pilot trial that provides 4 weeks of medically-tailored meals (MTM) to patients with heart failure (HF) via collaboration with the Philadelphia Meals on Wheels chapter to assess the feasibility of such an…
- Trial name
- NCT04289181
- Testing
- Medically Tailored Meals
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Thomas Jefferson University
Diabetes, Weight Loss
De Por Vida: A Diabetes Risk Reduction Intervention for Hispanic Women
This pragmatic randomized clinical trial will assess the efficacy, cost, and sustainability of a culturally tailored weight-loss program targeting obese Hispanic women with pre-diabetes or T2D.
- Conditions
- Diabetes, Weight Loss, PreDiabetes, Obesity
- Trial name
- NCT03113916
- Testing
- Behavioural Lifestyle Intervention
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obesity
Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments
Background Obesity and physical inactivity contribute substantially to cardiovascular disease risk, diabetes, hypertension, and dyslipidemia.
- Trial name
- NCT03288207
- Testing
- AMRA(r) Researcher Image reconstruction software, MRI: radiofrequency coils (Device Manufacturer: Siemens Medical Solutions USA, Inc.), MRI: Research pulse sequences (Device Manufacturer: NIH)
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pediatric Obesity
Study on the Tailored Intervention Strategy of Childhood Obesity Based on Monitoring Physical Activities and Dietary Behaviors
The project aims at developing the tailored intervention strategy of childhood obesity based on monitoring physical activities with accelerometer and dietary behaviors using diary.
- Trial name
- NCT02228434
- Testing
- Monitoring and Tailored prescription, Happy 10 program, Specified nutrition education
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Wang Jingjing