Clinical trials: Tailored Condition
Congestive Heart Failure
Peripheral Venous Oxygen Saturation and Biomarkers to Estimate Cardiac Output and Filling Pressures in Heart Failure
The relationship between peripheral venous saturation and central hemodynamics (including right and left heart filling pressures and cardiac output), mixed venous oxygen saturation, and contemporary biomarkers of heart failure is…
- Trial name
- NCT00595738
- Testing
- Standard of care therapy for severe decompensated heart failure
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer
The Andromeda Study.Predictive Value of Combined Criteria to Tailor Breast Cancer Screening.
Some women have a higher risk than others of developing breast cancer. Unhealthy lifestyles, high breast density, family history, obesity, the presence of biomarkers associated with early neoplastic changes (considered alone or…
- Trial name
- NCT02618538
- Where
- 4 sites in Italy
- Volunteers
- 26,600 people
- Sponsor
- Centro di Riferimento per l'Epidemiologia e la Prev. Oncologica Piemonte
Chronic Pain
Tailored Non-Pharmacotherapy Services for Chronic Pain
The RESOLVE study is a multicenter comparative effectiveness trial of two cognitive behavioral therapy-based chronic pain (CBT-CP) treatments delivered via telehealth modalities: 1) online program and 2) live, health coach-led…
- Trial name
- RESOLVE (NCT04523714)
- Testing
- Online CBT-CP based program, Virtual health coach-led CBT-CP based program
- Where
- 4 sites in United States
- Volunteers
- 2,333 people
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea
Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation Workers
The objective of this protocol is to conduct a focus group to identify OSA beliefs, attitudes, and knowledge among employees in the transportation industry on shift schedules.
- Trial name
- NCT05039528
- Testing
- Personalized OSA messages, Control
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Colorectal Cancer
Tailored Messaging for CRC Screening
This is a randomized controlled trial to to determine whether direct, tailored messaging to patients prior to scheduling colonoscopy will increase patient adherence to provider recommendation for screening colonoscopy.
- Trial name
- NCT03310892
- Testing
- Generic message, Tailored message
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Frailty, Sarcopenia
Promoting Autonomy Through ExerCisE (PACE) in Outpatient Geriatric Clinics
Physical inactivity is highly prevalent among older adults and is associated with declines in physical function, independence, quality of life, and social participation.
- Trial name
- PACE - OGC (NCT07787663)
- Testing
- PACE
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- Université du Québec a Montréal
Coronary Artery Disease
HeartHab, Can a Patient-tailored Application Support Coronary Artery Disease Patients During Rehabilitation?
The HeartHab study is a pilot trial in which coronary artery disease patients (n = 15-30) are given the HeartHab application. The HeartHab application is a smarthphone based mobile application that serves as a secondary…
- Trial name
- HeartHab (NCT02668757)
- Testing
- HeartHab application intervention
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Enrichment With Meaning-generating Activities, Rehabilitation as Usual
Enrichment of Day Centers in Community-based Psychiatry
This RCT study addresses the topic of improving the possibilities for people with severe mental illness (SMI) to be engaged in meaningful daily occupations at community-based activity (CBA) centers.
- Trial name
- NCT01732575
- Testing
- Enrichment with meaning-generating activities
- Volunteers
- 107 people
- Sponsor
- Lund University
Postthrombotic Syndrome
The Ideal Deep Venous Thrombosis (DVT) Study
In the Netherlands, 25.000 patients each year are diagnosed with Deep Venous Thrombosis (DVT). Elastic compression stocking (ECS) therapy reduces the incidence of post thrombotic syndrome (PTS) following DVT from 50% without ECS…
- Trial name
- IDEAL (NCT01429714)
- Testing
- Individually tailored duration of elastic compression therapy, Elastic compression therapy with a standard duration of 24 months
- Where
- 14 sites in Italy, Netherlands
- Volunteers
- 865 people
- Sponsor
- Maastricht University Medical Center
HIV (Human Immunodeficiency Virus), Geriatric
Promoting Aging and Thriving With HIV
The pilot is an intervention of a geriatric assessment and management tool (PATH) in outpatient HIV clinics.
- Conditions
- HIV (Human Immunodeficiency Virus), Geriatric, Geriatric Assessment, HIV
- Trial name
- PATH (NCT07192419)
- Testing
- Promoting Aging and Thriving with HIV (PATH)-Implementation of a Tailored Geriatric Assessment and Management Strategy for HIV Care Settings
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Weight Loss, Weight Regain
Testing a Tailored Approach to Long-Term Weight Loss Success
The purpose of this study is to develop and test an adaptive, individually tailored intervention to prevent weight regain in people who have intentionally lost weight.
- Conditions
- Weight Loss, Weight Regain, Obesity & Overweight
- Trial name
- NCT07577765
- Testing
- Adaptive weight regain prevention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity
Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments
Background Obesity and physical inactivity contribute substantially to cardiovascular disease risk, diabetes, hypertension, and dyslipidemia.
- Trial name
- NCT03288207
- Testing
- AMRA(r) Researcher Image reconstruction software, MRI: radiofrequency coils (Device Manufacturer: Siemens Medical Solutions USA, Inc.), MRI: Research pulse sequences (Device Manufacturer: NIH)
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity
Efficacy of a Web-based Tailored Weight Management Program
The primary objective of this study is to assess the benefit of using online, tailored behavioral weight management materials (Balance), in combination with nutritional materials (Balance and Nourish), in conjunction with a goal…
- Trial name
- NCT00284167
- Testing
- tailored web-based weight management intervention
- Where
- United States
- Volunteers
- 1,848 people, healthy volunteers welcome
- Sponsor
- Robert Wood Johnson Foundation
Colorectal Cancer (Diagnosis)
Medically Tailored Meals to Reduce Ultra-processed Food Intake in Colorectal Cancer Survivors
This research study is a three-arm, parallel-group randomized clinical trial that examines the feasibility and initial impact of consuming medically tailored meals to reduce intake of ultra-processed food and improve health and…
- Trial name
- MTM (NCT07701707)
- Testing
- MTM: Medically tailored meals, MTM plus Fresh Produce, Control group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Diabetes Type 2
Evaluation of a Closed-loop Insulin Delivery System at Home With Tailored Home Care Services in Poorly Controlled Type 2 Diabetes Patients (T2D)
Closed-loop insulin delivery system has the potential to improve the condition of many poorly controlled insulin-treated Type 2 Diabetes (T2D) patients.
- Trial name
- CLOSEAP+ (NCT04233229)
- Testing
- t:slim X2 with Control-IQ, home healthcare services, usual care for daily insulin treatment
- Where
- 10 sites in France
- Volunteers
- 43 people
- Sponsor
- Air Liquide Santé International
Hypertension
Tailored Drug Titration Using Artificial Intelligence
The purpose of the ARTERY Outcomes study is to compare optima-for-blood pressure (optima4BP), a clinical decision support system for hypertension (HTN) treatment optimization to standard of care in patients with essential HTN.
- Trial name
- NCT04223934
- Testing
- optima4BP
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Optima Integrated Health
Unhealthy Alcohol Use, Alcohol Use Disorders
Tailoring Screening, Brief Intervention, and Referral to Treatment for Medical ICU Survivors
Unhealthy alcohol use is present in up to 38% of the 4 million patients admitted to an American intensive care unit (ICU) each year in the US.
- Trial name
- NCT02465177
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Colorado, Denver
Breast Cancer
Web-based Screening and Tailored Support
The ever expanding breast cancer survivor population urges the health care system to develop (cost-)effective screening and management of convalescent care needs that can be easily implemented in conventional follow-up care.
- Trial name
- ENCOURAGE (NCT01834521)
- Testing
- Web-based screening and tailored support
- Where
- Netherlands
- Volunteers
- 128 people
- Sponsor
- University Medical Center Groningen
Miscarriage in First Trimester
Comprehensive Assessment of First Trimester Pregnancy Loss
The FIRST-CARE Study is a prospective research project conducted at Hospital de la Santa Creu i Sant Pau (Barcelona, Spain), aimed at better understanding the causes and consequences of first-trimester pregnancy loss…
- Trial name
- FIRST-CARE (NCT07293819)
- Where
- 2 sites in Spain
- Volunteers
- 225 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Retinitis Pigmentosa
Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis Pigmentosa
The aim of the study is to apply a novel clinical investigation protocol in patients with Phosphodiesterase 6A (PDE6A), PDE6B and Rhodopsin (RHO)-based retinitis pigmentosa.
- Trial name
- NCT06323772
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Tuebingen