Clinical trials: Taste Disorder
Hypogeusia
Free Fatty Acids: Short Exposure Study
This study will examine whether or not short, daily exposures change a person's ability to detect free fatty acids in a solution by its taste. Repeated exposure should improve a person's ability to detect free fatty acids.
- Trial name
- NCT01686113
- Testing
- NEFA, Sucrose
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Purdue University
Ovulation, Menstruation
Impact of Menstrual Phase on Oral Glucose Sensitivity
In this study we are determining whether the hormones associated with the phases of the menstrual cycle (menstruation \& ovulation) influence taste sensitivity to glucose.
- Trial name
- NCT06800690
- Testing
- Urinary Estrogen Level
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Obesity, Overweight
The Effects of GLP-1 Receptor Agonists on Chemosensory Function and Ingestive Behavior
The goal of this study is to explore whether of GLP-1 receptor agonist use is associated with differences in taste, smell, food preferences, appetite, food cravings, and responses to food cues in adults.
- Conditions
- Obesity, Overweight, Taste Perception, Olfaction
- Trial name
- NCT07611201
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity
Taste Physiology in Obese Volunteers Before and After Bariatric Surgery
The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery.
- Trial name
- NCT02902198
- Testing
- Glucose, Monosodium glutamate, Quinine
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University Hospital, Basel, Switzerland
Healthy Lifestyle, Taste Disorders
Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults
Personalized nutrition is one of the most up to date trends in human nutrition and gains much interest of general public and scientists as well.
- Conditions
- Healthy Lifestyle, Taste Disorders, Diet Habit
- Trial name
- NCT04145453
- Testing
- Intervention genotype personalized nutritional recommendations, Control Group 1 personalized nutritional recommendations, Control Group 2 general nutritional recommendations
- Where
- Poland
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Cirrhosis, Food Preferences
Feeding Behavior and Taste Sensitivity Before and After Liver or Renal Transplantation
This study evaluates the influence of the taste sensitivity, of food preferences and of the reward system on the energetic balance before and after liver transplantation in cirrhotic patients and after kidney transplantation in…
- Conditions
- Cirrhosis, Food Preferences, Taste Disorders, Protein-Energy Malnutrition
- Trial name
- GREFFE (NCT02931812)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
End Stage Renal Disease
Pilot Study of Taste Sensations in Patients With End-stage Renal Disease on Hemodialysis
Individuals on dialysis due to kidney failure have very prescriptive diets. These diets help increase dialysis effectiveness and help patients control blood levels of electrolytes including potassium and phosphate, acid-base…
- Trial name
- NCT03495271
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Purdue University
Oropharynx Cancer
Bitter Taste Receptors in Oropharynx Cancer
The aim of this work is to investigate the expression of the bitter taste receptors in p16-positive and negative oropharyngeal carcinomas (in comparison to healthy, local tissue).
- Trial name
- NCT05211427
- Testing
- Biopsy
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Hummel
Obesity
Quantitative Evaluation of Bitter Taste in Obesity
Although taste influences food choices and favours diseases like obesity, there is no consensus about the existence of correlations between bitterness and anthropometric variables.
- Trial name
- NCT03149666
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Diet, Healthy, Obesity
Olfactory and Taste Changes During Fasting Mimicking Diet (FMD)
Literature experiences demonstrated the impact of medically-assisted pulsed fasting on olfactory behavior in both the animal and human models and - conversely - the lack of homogeneous results linked - up to now - to…
- Conditions
- Diet, Healthy, Obesity, Olfaction Disorders
- Trial name
- FMD1 (NCT04529161)
- Testing
- Fasting Mimicking Diet (FMD), Routinary diet habits
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Uniter Onlus
Asthma, Croup
Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup
Study of the palatability and acceptability of dexamethasone oral tablets crushed and placed in apple sauce or pudding in comparison with the IV solution mixed with sugar syrup and given orally.
- Trial name
- NCT03705273
- Testing
- Dexamethasone IV for PO, Dexamethasone crushed tablets
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Stroke
Sour Taste and Cold Temperature in Dysphagia
The objective is to establish the effect of sour taste and cold temperature on the pharyngeal swallowing transit time after ischemic hemisphere stroke.
- Trial name
- NCT00780364
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Obesity
The Obese Taste Bud Study
The sense of taste is essential for priming food preferences and is therefore important for caloric uptake and body weight regulation.
- Trial name
- OTB (NCT04633109)
- Testing
- taste bud biopsy, oral glucose tolerance test, Taste sensitivity
- Where
- Germany
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Chemotherapy Side Effects, Taste, Altered
Taste Alterations Study
The main questions it aims to answer are: 1. Does completing a standard assessment increase the detection of chemotherapy induced taste changes compared with usual care (no assessment)? What TA are experienced? Are there any…
- Trial name
- TAS (NCT06669416)
- Testing
- Taste Alteration Self-Assessment, Taste Alternation Self-Management
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Wake Forest University Health Sciences
Melanoma, Non-small Cell Lung Cancer (NSCLC)
Taste and Smell Dysfunction in Patients More Than Two Years After Start of Immune Checkpoint Inhibitor Therapy
Background of the study: Immune checkpoint inhibitors (ICIs) are widely used as treatment for multiple cancer types and the number of patients with longterm disease control after ICIs is increasing.
- Conditions
- Melanoma, Non-small Cell Lung Cancer (NSCLC), Urogenital Cancers
- Trial name
- TasteSPICIER (NCT06495008)
- Testing
- no intervention, only questionnaires, saliva collection and taste/smell tests
- Where
- Netherlands
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Lichen Planus
Mucosal and Nasal Involvement and Their Correlation With Smell and Taste Functions in Lichen Planus Patients
This study investigates smell and taste function in patients diagnosed with lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes.
- Trial name
- LP-NOSE (NCT07570706)
- Testing
- Grup 1 - Lichen Planus Patients Intervention Name: Taste and Smell Testing, Oral and Nasal Examination, Nasal Endoscopy Intervention Description: Participants undergo taste and smell testing to assess
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
PCOS, Semaglutide
The Effects of Semaglutide on Taste, Tongue Tissue Transcriptome, Gastric Emptying and Central Neural Response in Women With PCOS and Obesity
The purpose of the study is to explore the effects of GLP-1 receptor agonist (GLP-1 RA) semaglutide on modulation of taste sensitivity, tongue tissue transcriptome, modulation of neural response in central reward processing…
- Conditions
- PCOS, Semaglutide, Taste, Altered, Tongue Tissue Transcriptome
- Trial name
- NCT04263415
- Testing
- Semaglutide
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Taste Disorders
Sensitivity of Basic Taste in Elderly
The purpose of this study is to identify the thresholds sensitivity of the five basic tastes in an elderly population and relate to food intake, nutritional status, age, gender and others variables.
- Trial name
- TASTE (NCT03196440)
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- Hospital Israelita Albert Einstein
Bipolar II Disorder
Differential Responses to Drugs and Sweet Tastes
Young adults who exhibit "bipolar phenotype" (BPP), defined as occasional episodes of mood elevation and heightened activity, are at risk for several psychiatric disorders, including problem use of drugs and alcohol.
- Trial name
- HAP (NCT03810703)
- Testing
- d-amphetamine 10 mg oral capsule, d-amphetamine 20 mg oral capsule
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Hyperaldosteronism; Primary, Hypertension
Investigating Salt Taste Threshold in Patients Being Investigated for Primary Hyperaldosteronism Before and After Treatment.
This study looks at how hypertensive patients, with high levels of aldosterone (hyperaldosteronism) differ from hypertensive patients without hyperaldosteronism with regards to markers of salt appetite.
- Conditions
- Hyperaldosteronism; Primary, Hypertension, Salt; Excess, Appetite Disorders
- Trial name
- AldoSalt (NCT04556279)
- Testing
- adrenalectomy, Aldosterone Antagonist
- Where
- United Kingdom
- Sponsor
- Imperial College London