Clinical trials: Taste Perception, open to volunteers
Radiation-induced Oral Mucositis
Hydroxychloroquine Sulfate Tablets for Radiation-induced Oral Mucositis
Evaluate the safety, tolerance and efficacy of hydroxychloroquine sulfate tablets the prevention and treatment of oral mucositis and dysgeusia in patients undergoing radiotherapy
- Trial name
- RIOM (NCT06939582)
- Testing
- Hydroxychloroquine Sulfate Tablets
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Xingchen Peng
Nasopharyngeal Carcinoma
ChemoRT With and Without Dental Stent for Taste Protection in NPC Patients
Primary objective: Evaluate and compare incidence of acute and long-term taste dysfunction in chemoradiation plus dental stent group vs.
- Trial name
- NCT06733948
- Testing
- Dental stent, No dental stent
- Where
- 2 sites in Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Chronic Cough
The Real-world Treatment Satisfaction by Gefapixiant in RCC
Chronic cough has a high global prevalence and it is refractory to such treatments by approximately 20% of patients. Gafapixant is a P2X3 receptor antagonist that has demonstrated the reduction of cough in patients with…
- Trial name
- NCT06542484
- Testing
- Gefapixant Citrate
- Where
- 2 sites in Japan
- Volunteers
- 63 people
- Sponsor
- Nagoya City University
Central Visual Impairment, Peripherical Visual Impairment
A Study of Taste- and Olfactory-Evoked Potentials in Patients With Visual Impairment: Taste, Smell, and Vision
Visual impairment, whether central or peripheral, may influence the plasticity of other sensory modalities, such as taste and smell.
- Conditions
- Central Visual Impairment, Peripherical Visual Impairment, Macular Retinal Dystrophy, Peripherical Macular Dystrophy
- Trial name
- GOUSTAVIS (NCT07707219)
- Testing
- Taste and smell evaluation, Recording of evoked potentials (EP)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Sensory Testing, Umami Taste
Energy Reduction and Umami
People tend to regulate intake by the weight of food rather than its energy content, making energy dense foods, especially those combining salty, fatty, and umami tastes, more likely to promote passive overconsumption.
- Conditions
- Sensory Testing, Umami Taste, Energy Density, Food Intake Measurement
- Trial name
- Season (NCT07438028)
- Testing
- Regular energy density, no added umami, Regular energy density, with added umami, Lowered energy density, with added umami
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Healthy
A Study to Learn How Different Preparations of Osivelotor Taste and Enter the Blood With Food or Liquids or With an Antacid in Healthy Adults
A study to learn how different preparations of osivelotor taste and enter the blood with food or liquids, or with an antacid in healthy adults.
- Trial name
- NCT06507904
- Testing
- Osivelotor, Famotidine
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pfizer
Head and Neck Cancer, Taste Dysfunction
Intraoral Hypothermia Device for Preserving Taste During Radiation
Radiation therapy to the head and neck region is known to cause taste dysfunction. Preliminary studies showed that cooling normal structures may lower damage caused by radiation.
- Conditions
- Head and Neck Cancer, Taste Dysfunction, Radiation Therapy
- Trial name
- NCT06579248
- Testing
- Intraoral Device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Henry Ford Health System
Health-Related Behavior
Alteration of Sweet Taste Perception After Reduction of Sweet Food and Beverage Consumption.
The goal of this clinical trial is to determine whether reducing sugar intake by 50% for 12 weeks can change sweet taste perception in healthy adults and its consequences.
- Trial name
- NCT06678386
- Testing
- 50% sugar reduction
- Where
- Thailand
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Taste Disorders, Breast Cancer
Incidence of Dysgeusia in Breast Cancer Patients Undergoing Chemotherapy
The goal of this observational study is to examine how frequently changes in taste occur in people with early-stage breast cancer who receive chemotherapy.
- Conditions
- Taste Disorders, Breast Cancer, Quality of Life, Taste Perception
- Trial name
- GustiAmo (NCT07317752)
- Testing
- Taste Assessment / Nutritional Assessment / Quality of Life Assessment
- Volunteers
- 40 people
- Sponsor
- Azienda Sanitaria Locale CN2 Alba-Bra
Dental Anesthesia, Sweet Taste Perception
Efficacy of Pre-cooling and Sweet-tasting Solution on Pain Related to Local Anesthesia Injection in Children
The study aims to determine whether pre-cooling and sweet-tasting solutions, alone or combined with topical anesthesia, provide better pain control during dental local anesthesia in children.
- Conditions
- Dental Anesthesia, Sweet Taste Perception, Pain and Anxiety, Behavioral Management
- Trial name
- NCT07835191
- Testing
- Dental anesthesia
- Where
- Egypt
- Volunteers
- 224 people
- Sponsor
- British University In Egypt
Cancer
Rehabilitation of Taste and Smell Disorders Associated With Chemotherapy Using Aromatherapy
Changes in taste and smell can occur during chemotherapy treatment. These chemotherapy-related side effects can negatively impact patients' quality of life and diet.
- Trial name
- AGORA (NCT07041710)
- Testing
- experimental in day hospital, taste and smell disorders questionnaire
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Médipôle Lyon-Villeurbanne
Multiple Myeloma, GI Cancer
Gustabor Phase 1 - AI-based Creation of a Nutritional Plan to Compensate for Chemotherapy-induced Taste Disorders
The study investigates taste disorders that commonly occur during or after cancer treatment, often leading to issues such as malnutrition and treatment discontinuation.
- Conditions
- Multiple Myeloma, GI Cancer, Taste Disorders
- Trial name
- GustaborPilot (NCT07040189)
- Testing
- Gustabor server
- Where
- 3 sites in Germany
- Volunteers
- 51 people
- Sponsor
- Wuerzburg University Hospital
Dysphagia, Stroke
Changes in Sensitivity, Taste and Smell in Stroke Patients
This study evaluates changes in swallowing using endoscopic swallowing studies and measuring of pharyngeal sensitivity, taste and smell in stroke patients.
- Trial name
- 5S (NCT03240965)
- Testing
- FEES (flexible endoscopic evaluation of swallowing), Sensitivity threshold, Taste-/smell-test
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Obesity
Mechanisms Underlying Individual Variations of Taste and Smell in Obesity
Background: Changes to the sense of taste or smell can change eating behavior. This may contribute to obesity. Researchers want to see how taste and smell perceptions that affect food choices may differ between people with…
- Trial name
- NCT04714892
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Plaque Induced Gingival Disease
Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis
This randomized controlled clinical trial aims to compare the taste acceptance and clinical effectiveness of hyaluronic mouthwash and chlorhexidine mouthwash in children with plaque-induced gingivitis.
- Trial name
- NCT07662226
- Testing
- Hyaluronic Acid mouthwash, Chlorohexidine 0.12% mouthwash
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pancreatic Cancer
Personalised Nutritional Care in Older Patients With Pancreatic Ductal Adenocarcinoma
NutriCa65-PDAC is a clinical study for patients aged 65 years or older with pancreatic ductal adenocarcinoma, a type of pancreatic cancer.
- Trial name
- NutriCa65-PDAC (NCT07821554)
- Testing
- Experimental: Personalised nutritional care delivered by a trained dietitian
- Where
- 5 sites in Denmark, Italy and 3 more
- Volunteers
- 250 people
- Sponsor
- Inna Chen, MD
Taste Alterations, Smell Disorder
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents
Childhood cancer is a serious and life-changing disease that affects thousands of children every year worldwide. In addition to the disease itself, cancer treatments such as chemotherapy often cause difficult side effects.
- Conditions
- Taste Alterations, Smell Disorder, Eating Behavior Changes
- Trial name
- QUALISENS (NCT07490093)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Leon Berard
Acupuncture, Taste Disorders
Hypoglossal Acupuncture for Dysgeusia in Patients Undergoing Chemotherapy
This randomized controlled trial aims to investigate hypoglossal acupuncture in comparison to sham acupuncture and standard medical treatment (dietary recommendations) in the treatment of dysgeusia in cancer patients undergoing…
- Conditions
- Acupuncture, Taste Disorders, Dysgeusia, Chemotherapy
- Trial name
- OralAcu (NCT02304913)
- Testing
- Hypoglossal acupuncture, Dietary recommendations
- Where
- 3 sites in Germany
- Volunteers
- 75 people
- Sponsor
- Universität Duisburg-Essen
Cognitive Disorders
Single-center Prospective Longitudinal Study of Taste in Patients With Cognitive Disorders at Different Stages of Severity (Isolated Cognitive Complaint, Minor or Major Neurocognitive Alzheimer-type Disorders) by Analysis of Gustatory Evoked Potentials
The aim of the MAPEG 2 study is to explore gustatory function and to follow its evolution in the 4 following groups of participants: Healthy subjects Participants with isolated cognitive complaint Participants with minor…
- Trial name
- MAPEG 2 (NCT05888961)
- Testing
- Blood samples, Interviewing the subject and scales, Neurocognitive evaluation
- Where
- France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Diabetes
Taste Bud-Derived Stem Cells in Humans
Background: Stem cells are found in body tissues. They can regenerate into more of the same cells or become other types of cell. Researchers want to use stem cells from taste buds to try to make cells that secrete insulin.
- Trial name
- NCT03366168
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)