Clinical trials: Taste Perception, active
Taste Alterations, Smell Disorder
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents
Childhood cancer is a serious and life-changing disease that affects thousands of children every year worldwide. In addition to the disease itself, cancer treatments such as chemotherapy often cause difficult side effects.
- Conditions
- Taste Alterations, Smell Disorder, Eating Behavior Changes
- Trial name
- QUALISENS (NCT07490093)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Leon Berard
Oral Health, Tast Perference
The Effect of Body Mass Index on Taste Perception,Salivary Hormones and Oral Health Status
the goal of the study is to test the effect of body mass index on adolesent Iraqi student girls by measuring salivary hormones (ghrelin,leptin,resistin)and measuring oral health by plague index score() and taste perception score…
- Trial name
- NCT06949917
- Testing
- body mass index for age
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Chronic Cough
The Real-world Treatment Satisfaction by Gefapixiant in RCC
Chronic cough has a high global prevalence and it is refractory to such treatments by approximately 20% of patients. Gafapixant is a P2X3 receptor antagonist that has demonstrated the reduction of cough in patients with…
- Trial name
- NCT06542484
- Testing
- Gefapixant Citrate
- Where
- 2 sites in Japan
- Volunteers
- 63 people
- Sponsor
- Nagoya City University
Diabetes
Taste Bud-Derived Stem Cells in Humans
Background: Stem cells are found in body tissues. They can regenerate into more of the same cells or become other types of cell. Researchers want to use stem cells from taste buds to try to make cells that secrete insulin.
- Trial name
- NCT03366168
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Healthy Diet
Monell USDA Taste Test Study
Overconsumption of carbohydrates has been implicated as a cause of significant public health problems including obesity and diabetes. The most effective approach to alter dietary pattern and improve public health is unknown.
- Trial name
- MUTT (NCT04079855)
- Testing
- Diet composition 1, Diet composition 2, Diet composition 3
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- David Baer
Obesity
Taste Physiology in Obese Volunteers Before and After Bariatric Surgery
The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery.
- Trial name
- NCT02902198
- Testing
- Glucose, Monosodium glutamate, Quinine
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University Hospital, Basel, Switzerland
Chemotherapy Side Effects, Taste, Altered
Taste Alterations Study
The main questions it aims to answer are: 1. Does completing a standard assessment increase the detection of chemotherapy induced taste changes compared with usual care (no assessment)? What TA are experienced? Are there any…
- Trial name
- TAS (NCT06669416)
- Testing
- Taste Alteration Self-Assessment, Taste Alternation Self-Management
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Wake Forest University Health Sciences
Healthy Adults
Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines
Many people, particularly small children, must take drugs in liquid form because they cannot swallow pills or capsules. The bad taste of some liquid drugs can keep patients from taking drugs they need for their health.
- Trial name
- NCT06929455
- Testing
- Flavor additives
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Head and Neck Cancer, Taste Dysfunction
Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy
Patients diagnosed with head and neck cancer who receive radiation therapy with and without chemotherapy develop altered sense of taste due to treatment effect, which typically arises in the second week of radiation therapy and…
- Trial name
- NCT05273307
- Testing
- Miraculin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Health-Related Behavior
Alteration of Sweet Taste Perception After Reduction of Sweet Food and Beverage Consumption.
The goal of this clinical trial is to determine whether reducing sugar intake by 50% for 12 weeks can change sweet taste perception in healthy adults and its consequences.
- Trial name
- NCT06678386
- Testing
- 50% sugar reduction
- Where
- Thailand
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Teeth Staining, Numbness of the Tongue and Soft Tissue
Children Acceptance of AgNP Mouthwash Against Chlorhexidine 0.12% and Chlorhexidine .2% Mouthwashs
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine 0.12% \& Chlorhexidine 0.2%
- Conditions
- Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste
- Trial name
- NCT07200063
- Testing
- nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Cairo University
Central Visual Impairment, Peripherical Visual Impairment
A Study of Taste- and Olfactory-Evoked Potentials in Patients With Visual Impairment: Taste, Smell, and Vision
Visual impairment, whether central or peripheral, may influence the plasticity of other sensory modalities, such as taste and smell.
- Conditions
- Central Visual Impairment, Peripherical Visual Impairment, Macular Retinal Dystrophy, Peripherical Macular Dystrophy
- Trial name
- GOUSTAVIS (NCT07707219)
- Testing
- Taste and smell evaluation, Recording of evoked potentials (EP)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Multiple Myeloma (MM), GI Cancer
Gustabor Phase 2 - Treating Taste Changes During Cancer Therapy: A Randomized Study Evaluating an AI- Based Nutrition Intervention
The study investigates taste disorders that commonly occur during or after cancer treatment, often leading to issues such as malnutrition and treatment discontinuation.
- Conditions
- Multiple Myeloma (MM), GI Cancer, Taste Disorder, Melanoma (Skin Cancer)
- Trial name
- GustaborRCT (NCT07649681)
- Testing
- Gustabor server, Standard Recommendations
- Where
- 6 sites in Germany
- Volunteers
- 198 people
- Sponsor
- Wuerzburg University Hospital
Elevated Blood Pressure, Vascular Health
Sodium-rich COndiments Unifying Health and Taste
This research aims to develop an evidence-based classification for sodium-rich condiments (natremic index) based on their CVD-related risks.
- Conditions
- Elevated Blood Pressure, Vascular Health, Sensory Evaluation
- Trial name
- Scout (NCT07397754)
- Testing
- Control porridge with no condiments, Porridge with light soya sauce, Porridge with fermented bean paste
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Alcohol Use Disorder
Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)
Background: Alcohol use disorder (AUD) is the most common substance use disorder in the world. Long-term AUD can affect a person s sense of taste and smell.
- Trial name
- NCT05677321
- Where
- United States
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Dietary Behavior, Free Sugar
This Trial Aims to Assess the Effects of Three Different Taste-based Dietary Recommendations for Reducing Free Sugar Intakes on Free Sugar Consumption in UK High Free Sugar Consumers
This randomised controlled trial aims to assess the effects of three different taste-based dietary recommendations for reducing free sugar intakes on free sugar consumption in UK high free sugar consumers.
- Conditions
- Dietary Behavior, Free Sugar, Sweet Taste
- Trial name
- NCT06925932
- Testing
- Dietary advice - Sweet taste, Dietary advice - Taste, Dietary advice - No taste
- Where
- United Kingdom
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Dysphagia, Stroke
Changes in Sensitivity, Taste and Smell in Stroke Patients
This study evaluates changes in swallowing using endoscopic swallowing studies and measuring of pharyngeal sensitivity, taste and smell in stroke patients.
- Trial name
- 5S (NCT03240965)
- Testing
- FEES (flexible endoscopic evaluation of swallowing), Sensitivity threshold, Taste-/smell-test
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Metastatic Triple Negative Breast Cancer, Metastatic Testicular Cancer
The TASTY-steering Study
This is a multicentre non-blinded randomised intervention trial with a parallel cluster design. The multicentre study will be performed at 12 hospitals in the Netherlands.
- Conditions
- Metastatic Triple Negative Breast Cancer, Metastatic Testicular Cancer, Stage II-IV Diffuse Large B Cell Lymphoma
- Trial name
- TASTY-steering (NCT07258563)
- Testing
- Taste steering
- Where
- 11 sites in Netherlands
- Volunteers
- 201 people
- Sponsor
- University Medical Center Groningen
Obesity / Overweight, Obesity (BMI Equal to or >30)
A PHASE 2A, EXPLORATORY, RANDOMIZED, SINGLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY OF WEIGHT LOSS INDUCED BY NKS-3 IN OBESE ADULTS.
This study is designed as a single-blind, placebo-controlled, randomized, parallel-group trial. Subjects will be randomized in a 2:1 ratio to receive either NKS-3 or matching placebo, with a total planned enrollment of 31…
- Trial name
- SERENITY-1 (NCT07882654)
- Testing
- Investigational product is a modified linoleic acid, named NKS-3. This non-caloric agent, synthetized from linoleic acid, is a fat taste receptors agonist, targeting CD36 with also an impact on GPR120
- Where
- Tunisia
- Volunteers
- 31 people
- Sponsor
- EktaH
Healthy
A Study to Learn How Different Preparations of Osivelotor Taste and Enter the Blood With Food or Liquids or With an Antacid in Healthy Adults
A study to learn how different preparations of osivelotor taste and enter the blood with food or liquids, or with an antacid in healthy adults.
- Trial name
- NCT06507904
- Testing
- Osivelotor, Famotidine
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pfizer