Clinical trials: Teenagers
Obesity, Childhood, Pediatric Obesity
Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers
The US Preventive Services Task Force (USPSTF) recommends that providers screen children aged 6 years and older for obesity and offer or refer them to a comprehensive behavioral intervention (≥26 hours over a period of up to 12…
- Conditions
- Obesity, Childhood, Pediatric Obesity, Childhood Obesity, Adolescent Obesity
- Trial name
- TEAM UP (NCT03843424)
- Testing
- eSOC program, FBT program
- Where
- 7 sites in United States
- Volunteers
- 1,460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Opioid Free Anesthesia
Opioid-Free Anesthesia Versus Opioid Based Anesthesia For Adolescent Idiopathic Scoliosis
Opioid-free anesthesia (OFA) is a multimodal analgesic approach designed to eliminate the intraoperative use of systemic, neuraxial, or intracavitary opioids.
- Trial name
- NCT07389096
- Testing
- Dexmedetomidine, Fentanyl (IV)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nashwa Ahmed
Idiopathic Adolescent Scoliosis, Idiopathic Juvenile Scoliosis
Minimal Invasive Scoliosis or Open Surgery
Surgical treatment for idiopathic scoliosis usually involves open surgery from the back (posterior approach). This method corrects the curve and stabilizes the spine using screws and rods, followed by a fusion of the treated…
- Trial name
- MISCOS (NCT07203586)
- Testing
- Minimally invasive scoliosis surgery, Traditional open scoliosis surgery group
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Uppsala University
Adolescent Idiopathic Scoliosis
COMPARISON OF THE EFFECTIVENESS OF CLINICAL AND HOME-BASED SCHROTH EXERCISES ON ADOLESCENT IDIOPATHIC SCOLIOSIS INDIVIDUALS
In individuals diagnosed with AIS, significant regressions in curvature were observed with the use of schroth exercises and brace.
- Trial name
- NCT06187623
- Testing
- Clinic based exercise, Home based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uskudar University
Mental Health Issue
The Effect of Increasing Physical Activity or Reducing Mobile Phone Use on Mental Health in Young People in Austria
Introduction: Data show adolescent mental health has declined in recent years, possibly due to increased uncertainty and loss of opportunities.
- Trial name
- SPARKY (NCT06153524)
- Testing
- Physical activity, Smartphone time
- Where
- Austria
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Asthma
Study to Evaluate Tezepelumab in Adults & Adolescents With Severe Uncontrolled Asthma
A Multicentre, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults and Adolescents with Severe Uncontrolled Asthma
- Trial name
- NAVIGATOR (NCT03347279)
- Testing
- Experimental: Tezepelumab
- Where
- 289 sites in United States, Argentina and 16 more
- Volunteers
- 1,061 people
- Sponsor
- AstraZeneca
Obesity
Effect of Different Intensities of Exercise on Daily Energy Expenditure With Physical Activity in Overweight Boys
The main purpose of this study is evaluate the effect of different intensities of exercise (moderate vs. intense) on the daily energy expenditure in overweight adolescents.
- Trial name
- PAPPAS2 (NCT02272088)
- Testing
- physical activity-moderate, Intense physical activity
- Volunteers
- 24 people
- Sponsor
- Rio de Janeiro State University
Bipolar Disorder
Placebo Controlled Trial of Valproate and Risperidone in Young Children With Bipolar Disorders
The primary aim of this proposal is to conduct a preliminary controlled trial of valproate and risperidone in children ages 3-7 yr. with bipolar disorders.
- Trial name
- NCT00221403
- Testing
- Risperidone oral solution, Valproate Oral Solution
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Adenovirus, Primary Immune Deficiency Disorder
Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection
Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered intravenously in in children, adolescents and young adults with…
- Trial name
- NCT03266627
- Testing
- cytotoxic t-lymphocytes
- Where
- 10 sites in United States
- Volunteers
- 20 people
- Sponsor
- New York Medical College
Depression, Subclinical Depressive Symptoms
Cognitive Training Video Game to Target Subclinical Depressive Symptoms in Youth
The purpose of the study is to determine how cognitive control training (CCT) changes behavior in youth with subclinical depressive symptoms.
- Trial name
- NCT05697627
- Testing
- Computerized cognitive training (CCT) using EndeavorRx
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Michigan
Mb Crohn, Ulcerative Colitis (UC)
Uneven Nutrition and Life Style as IBD Triggers in Adolescents and Adults
The aims of the study are 1. to determine the effect on dysbiosis, permeability and inflammatory activity after administration of a Mediterranean like diet (a Nordic equivalent, "Nordiet"), 2.
- Trial name
- UNITA (NCT07389161)
- Testing
- Nordiet
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Region Skane
Obesity in Adolescents
Impact of a Targeted Nutritional Intervention on Glycaemic Variability and Correlation Between Glycaemic Parameters and Satiety.
Obesity affects 18% of French adults and increasingly impacts adolescents. Dietary management is challenging, particularly with eating disorders like hyperphagia.
- Trial name
- APETIT (NCT07771842)
- Testing
- The primary intervention in this study is dietary counseling and education on adopting a low glycaemic index diet with sample menus provided, continuous glucose monitoring (CGM) sensors
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Healthy, Condom Use
Nen ŨnkUmbi/EdaHiYedo Plus (We Are Here Now Plus): a Multi-level Intervention to Reduce Health Disparities Among American Indian Youth
We Are Here Now - Plus (NE+) is a holistic, culturally centered, and multilevel intervention for American Indian youth to improve sexual health, mental health, and substance use outcomes.
- Conditions
- Healthy, Condom Use, Mental Health, Substance Use (Drugs, Alcohol)
- Trial name
- NE+ (NCT07460973)
- Testing
- NE+, Control
- Where
- United States
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- Montana State University
Athletic Performance, Soccer
Acute Effects of Isometric Conditioning on Sprint, Jump and Change of Direction Performance in Youth Soccer Players
This study aims to examine the acute effects of an isometric conditioning activity on sprinting, jumping, and change-of-direction performance in elite youth soccer players.
- Conditions
- Athletic Performance, Soccer, Isometric Strength Training
- Trial name
- NCT07482254
- Testing
- Isometric Conditioning Activity, Control Condition
- Where
- Poland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Type 2 Diabetes
Type 2 Continuous Glucose Monitoring Academy
The goal of this clinical trial is to evaluate the Impact of Continuous Glucose Monitoring Academy Education Curriculum Versus Standard Care on Glycemic Outcomes for Youth With Type 2 Diabetes (T2D): The first aim is to determine…
- Trial name
- NCT06516640
- Testing
- Continuous Glucose Monitoring Academy, Standard Education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Los Angeles
Cystinosis
Neuromuscular Characterisation in Late Adolescent and Adult Cystinosis Patients
The primary objective of the study is to evaluate the change in motor function of patients with cystinosis. The secondary objectives of the study: assessment of the respiratory function; assessment of the muscle function…
- Trial name
- Cystinose (NCT05545774)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stress, Anxiety
Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer
The goal of this study is to find the best way to help participants and families manage the stress of facing a serious illness and be better able to "bounce back" or be resilient after a difficult situation.
- Trial name
- NCT06038318
- Testing
- PRISM Program Video Coach, PRISM Program Text Coach, mPRISM Program App
- Where
- 2 sites in United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Depression, Anxiety
Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services
The primary aim of this study is to determine the feasibility and acceptability of the W-GenZD mobile application among a group of adolescents and who have screened and triaged into low-intensity treatment within the Children's…
- Trial name
- NCT05372913
- Testing
- Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Woebot Health
Type1 Diabetes Mellitus
Comparison of Real-time CGMS With Intermittently-scanned CGMS in Adolescents and Adults With Type 1 Diabetes Mellitus
Type 1 Diabetes Mellitus (T1DM) is characterized by absolute insulin deficiency. Despite multiple daily insulin injections, glycemic targets are usually not achieved in T1DM patients.Use of continuos glucose monitoring system…
- Trial name
- NCT05928260
- Testing
- Medtronic Guardian Connect Sensor 3, Abott Freestyle Libre Sensor, Self blood Glucose monitoring by a glucometer
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Autoimmune Thyroiditis
Oxidative Status in Children With Autoimmune Thyroiditis
Oxidative status in autoimmune thyroiditis was not investigated previously in children and adolescents. We investigated oxidant and antioxidant systems in a cohort of Egyptian children and adolescents with AIT to explore their…
- Trial name
- NCT02318160
- Testing
- measurement of oxidant status in AIT
- Volunteers
- 64 people
- Sponsor
- Assiut University
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