Clinical trials: Teeth Loss
Tooth Loss
Ridge Expansion in the Maxillary Aesthetic Zone Using Piezo-electric Surgery
In this split-mouth controlled study, implants placed using the alveolar ridge expansion technique will be compared to those placed in native bone with sufficient horizontal bone width.
- Trial name
- NCT01796119
- Testing
- Ridge Splitting, Implants placed using drilling technique
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinique Dentaire et d'implantologie Dr.Vinh Nguyen
Bone Loss, Tooth Movement
The Introduction of a Novel PAOO Technique
The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated…
- Trial name
- NCT05264480
- Testing
- Bone augmentation with minimally invasive corticotomy (piezotomy), Bone augmentation without corticotomy
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Tooth Loss
Removable Partial Dentures Made of PEEK
As part of the clinical study, 25 patients each were provided with removable partial dentures with clasps made of PEEK in two centres (University Hospital Heidelberg, Department of Prosthodontics and University Hospital for…
- Trial name
- KLAP (NCT06191107)
- Testing
- Removable Partial Denture
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Missing Teeth, Dentures
Comparison Between Conventional and CAD/CAM Complete Dentures Designed Based on Neutral Zone Concept
A within-subject cross-over study is done on eight completely edentulous patients to compare two different complete removable dentures.
- Trial name
- NCT05990088
- Testing
- Heat Cured Conventional Polymethylmethacrylate Complete Removable Dentures based on neutral zone concept, CAD/CAM Milled Methacrylate Complete Removable Dentures based on neutral zone concept.
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Teeth Absent, Tooth-loss
Peri-implant Tissues on the Galimplant Anti-rotational Slim Abutment.
A dental implant is an alloplastic material surgically inserted in a residual bone ridge, mainly with a prosthetic foundation. Nowadays the most widely used implants and with a higher degree of scientific evidence are the…
- Conditions
- Teeth Absent, Tooth-loss, Tooth Extraction, Dental Implant
- Trial name
- NCT05118815
- Testing
- Slim abutment, Standard abutment
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Bone Loss, Alveolar
L-PRF in Alveolar Ridge Preservation
The effect of leucocyte- and platelet-rich fibrin (L-PRF) for enhancing the healing after dental extractions is still a matter of debate.
- Trial name
- L-PRF (NCT03408418)
- Testing
- Platelet-rich fibrin
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Missing Teeth
Evaluation Of Innovative 3D Printed Space Maintainer Versus Conventional One
The primary aim of this study is to introduce a new effective and efficient 3D printed design of an intra-oral space maintainer.
- Trial name
- NCT04221243
- Testing
- 3D printed space maintainer by NextDent Ortho Rigid, Conventional Band and Loop
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Farah Ahmed Barakat
Periodontal Pocket, Periodontal Bone Loss
Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets
To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal…
- Conditions
- Periodontal Pocket, Periodontal Bone Loss, Impacted Third Molar Tooth
- Trial name
- NCT06318247
- Testing
- site preservation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Missing Teeth
Single-retainer Lithium Di-silicate Versus Zirconia Resin Bonded Bridge for Replacement of an Anterior Missing Tooth.
First, Participants in this study will be recruit according to inclusion criteria. Proper examination for the participants (clinically and radiographically). Preparation for abutment tooth for Resin bonded fixed partial denture.
- Trial name
- RBFPD (NCT05861921)
- Testing
- Single-retainer Lithium Di-silicate Resin Bonded Fixed Partial Denture
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
The aim of this trial is to compare whole-tooth vs particulate dentin for their effects in alveolar ridge preservation.
- Trial name
- NCT05336149
- Testing
- Alveolar ridge preservation using whole-tooth dentin graft, Alveolar ridge preservation using particulate dentin graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Unsatisfactory or Defective Restoration of Tooth
Minimal Invasive Rehabilitation of Tooth Loss in the Posterior Segment (MIZE-S)
Tooth loss can be addressed by different rehabilitative strategies. Implant-supported crowns and conventional bridges (fixed dental prostheses [FDPs]) are well established treatment alternatives.
- Trial name
- MIZE-S (NCT01997710)
- Testing
- all-ceramic inlay-retained RBFDP, all-ceramic RBFDP
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Caries Active, Tooth Decay
Effects of Platelet and Leukocyte-rich Fibrin on Alveolar Ridge Maintenance Through Three-dimensional Analysis
Understanding, through accurate and reliable volumetric analysis, how the biomaterial (LPRF) and the thickness of the vestibular bone plate influence changes in bone volume after extraction, is essential for making clinical…
- Conditions
- Caries Active, Tooth Decay, Tooth Loss / Rehabilitation
- Trial name
- NCT07278180
- Testing
- Alveolar socket preservation with graft and flap surgery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Tooth Loss
Effect of Zirconia Implant Supported PEKK Crowns Versus Lithium Disilicate Crowns on Esthetics
aim of study is to evaluate esthetic and biomechanical outcome of maxillary anterior single-tooth zirconia implant supported PEKK crowns compared to lithium disilicate crowns on PEKK abutments .
- Trial name
- NCT03521024
- Testing
- poly ether ketone ketone, lithium disilicate
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Pathological Conditions, Anatomical
Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation Procedures
The purpose of this study is to examine if a biologically active commercially available amnion chorion membrane (ACM) is as effective as the commercially available inert dense polytetrafluoroethylene membrane (D-PTFE) in…
- Trial name
- NCT02602223
- Testing
- Placing Amnion chorion membrane over grafted site, Placing d-PTFE membrane over grafted site
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Indiana University
Tooth Loss
Hard and Soft Tissue Maintenance Around Implants With a Sloped Configuration
This study is a controlled, randomized clinical trial over about 16-months (active phase). 40 patients in need of replacement of a single tooth with a minimal crestal bone width of 4 - 5mm and suitable for simultaneous GBR…
- Trial name
- NCT04712565
- Testing
- Astra Tech Implant System Profile EV, Astra Tech Implant System EV
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Tooth Loss, Recession, Gingival
Soft Tissue Volume Gain and Stability Comparing Palate and Tuberosity
The goal of this study is to compare clinical and histologically the soft tissue changes in terms of volume gain and stability around dental implants in cases where a subepithelial connective tissue graft from the palate or from…
- Trial name
- NCT03090906
- Testing
- Soft tissue augmentation palate, Soft tissue augmentation tuberosity, Intraoral optical scan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Edentulous Jaw, Tooth Loss
Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites
The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time.
- Conditions
- Edentulous Jaw, Tooth Loss, Toothless Mouth
- Trial name
- NCT07177521
- Testing
- Insertion of implants in post-extraction tooth
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Tooth Loss
Harnessing Chronomodulation to Enhance Osteogenesis
Chronotherapy is an emerging field in biomedicine that leverages on fine-tuning the timing of drug delivery to obtain a therapeutic effect. Dr.
- Trial name
- NCT03911336
- Testing
- Group A - test:Tooth extraction and intake of NSAID and a non-NSAID, Group B - Control 1: tooth extraction and intake of NSAID and a non-NSAID, Group C - Control 2: tooth extraction and intake of a Non-Nsaid
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Tooth Loss, Partial Edentulism in the Maxilla or in the Mandible
Evaluation of Autogenous Bone Graft on Immediate Dental Implant Osseointegration Using Piezosurgery
This clinical study aims to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar sites.
- Trial name
- ABG-IDIP (NCT07705399)
- Testing
- Immediate implant with autogenous bone graft, Immediate implant without bone graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Alveolar Bone Loss
Alveolar Ridge Preservation After Tooth Extraction
Post-extractive alveolar ridge remodeling represents a physiological phenomenon that may hamper successive implant insertion. Several techniques have been proposed without any significant difference of efficacy among them.
- Trial name
- CRES-PRES (NCT06546826)
- Testing
- BARP, simple tooth extraction, tooth root and PRF
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy