Clinical trials: Teeth Sensitivity
Dentin Sensitivity
A Clinical Study of Two Dentinal Hypersensitivity Treatments Used With Normal Oral Hygiene
This study will compare the safety and effectiveness of normal oral hygiene with two different marketed dentifrices, on longer term dentinal hypersensitivity response following use of potassium oxalate desensitizers.
- Trial name
- NCT02221349
- Testing
- Potassium oxalate, Sodium fluoride paste, Stannous fluoride paste
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Sensitivity, Tooth
Evaluation of Gluma Desensitizer in Post-treatment Sensitivity in Posterior Composite
To evaluate the effect of Gluma desensitizer in controlling immediate post-treatment sensitivity in posterior occlusal composite restorations.
- Trial name
- NCT04248803
- Testing
- GLUMA (Kulzer GmbH, Germany) desensitizing agent
- Where
- India
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Dentin Hypersensitivity
Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity
This study will be performed to assess the effect of inert prepared tooth paste loaded with Calcium Silicate Nanoparticles (CSNPs) and compare it to another one containing Sodium Fluoride Nanoparticles in the management of…
- Trial name
- NCT06557980
- Testing
- toothpaste
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Diabetes Mellitus, Sarcoidosis
Salivary Proteins in Disease and Health
This study will examine saliva samples from healthy volunteers and patients with various diseases to learn more about how disease affects the mouth and salivary glands.
- Conditions
- Diabetes Mellitus, Sarcoidosis, Dental Caries, Sjorgren's Syndrome
- Trial name
- NCT00100204
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Tooth Sensitivity
Effect of CPP-ACP Associated With NaF or SnF₂ on Post-Bleaching Tooth Sensitivity
This randomized, triple-blind, placebo-controlled clinical trial aims to evaluate the efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) associated with sodium fluoride (NaF) or stannous fluoride (SnF₂) in…
- Trial name
- NCT07506850
- Testing
- CPP-ACPF, CPP-ACP+SnF2
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Tooth Sensitivity
IN-OFFICE TOOTH BLEACHING WITH 37% CARBAMIDE PEROXIDE
Objectives: This study will determine the clinical efficacy of bleaching agent 37% carbamide peroxide compared to 35% hydrogen peroxide on the change of color scores in anterior superior teeth, in-office bleaching technique after…
- Trial name
- NCT02935114
- Testing
- 37% Carbamide Peroxide, 35% hydrogen Peroxide
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Toothache, Tooth Bleaching
Naproxen on Tooth Sensitivity Caused by In-office Bleaching
This study aims to evaluate the effects of prior use of non-steroidal anti-inflammatory Naproxen on risk and level of tooth sensitivity caused by in-office bleaching procedures.
- Trial name
- NCT02463552
- Testing
- Naproxen
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dentin Hypersensitivity, Tooth Discoloration
Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies
This study evaluates the effectiveness of Scigates foam mouth sanitizer 2 in 1 toothpaste and mouthwash in reducing tooth sensitivity and improving tooth whitening compared to Lacalut® White \& Repair toothpaste.
- Trial name
- NCT07511530
- Testing
- Scigates Foam Mouth Sanitizer 2 in 1 Toothpaste and Mouthwash, Lacalut White and Repair Toothpaste
- Where
- Jordan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Prof. Mayyas Al-Remawi
Bad Breath, Tooth Sensitivity
A Clinical Trial to Evaluate the Effects of Larineco Remineralizing Gum on Oral Health, Breath Freshness, Tooth Sensitivity, and Gum Comfort
This is a single-group, open-label, decentralized (virtual) clinical trial evaluating the effects of Larineco Remineralizing Gum on self-reported oral health outcomes in 40 generally healthy adults aged 18-57 years who experience…
- Trial name
- NCT07692581
- Testing
- Larineco Remineralizing Gum
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Larine C Corporation
Composite Resins, Teeth Sensitivity
Clinical Evaluation of Short Fiber-Reinforced Composite Restorations With and Without Preheating Approach
To clinically evaluate the performance of preheated versus non-preheated short fiber-reinforced composite (SFRC) restorations in Class I posterior cavities over a 12-month period
- Conditions
- Composite Resins, Teeth Sensitivity, Restoration Design, Composite Restoration
- Trial name
- NCT07496047
- Testing
- Preheated everX Posterior composite, Non-preheated everX Posterior composite
- Where
- 2 sites in Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tanta University
Periodontal Disease, Dentin Sensitivity
Dentin Hypersensitivity Following Non-surgical Periodontal Therapy With Hand or Ultrasonic Instruments
Periodontal instrumentation aims to remove plaque and calculus from the root surface. Both manual and ultrasonic instruments have been used for such decontamination; however, establishing a healthy periodontium can result in…
- Trial name
- NCT01427764
- Testing
- manual and ultrasonic instruments
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Escola Bahiana de Medicina e Saude Publica
Sensitivity, Tooth
To Assess the Efficacy of a Toothpaste Containing 8% Arginine as Compared to Colgate Cavity Protection Toothpaste in the Reduction of Dentinal Hypersensitivity.
The objective of this clinical investigation is to assess the efficacy of a toothpaste containing 8% arginine (Colgate-Palmolive Company, New York, NY, USA) as compared to a commercially available non-desensitizing toothpaste…
- Trial name
- NCT07149376
- Testing
- TOMs of Maine Sensitive SLS Free Xtra Fresh, Colgate Cavity protection toothpaste
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Pain
The Effect of Oxalic Acid on Cervical Restorations
The aim of this double-blind randomized controlled clinical trial was to evaluate the effect on dentin sensitivity using oxalic acid desensitizing agent before restoring with resin-based-composites, during one-year follow-up.
- Trial name
- OxalicAc (NCT02306486)
- Testing
- with 0,5% oxalic acid (Desenssiv SSWhite)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Chile
Dental Restoration Failure of Marginal Integrity
Different Application Strategies When Using Ambar Universal in Class V Cavities
Treatment clinical trial, randomized, controled, parallel, double-blinded, with four groups, that aims to evaluate the best application strategy when using a new Universal Adhesive system, Ambar Universal (FGM, Joinville…
- Trial name
- AUC (NCT02948686)
- Testing
- Self-Etching Application Strategy, Enamel Etching Application Strategy, Self Etching with Extended time Application Strategy
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Inflammation
Anti-inflammatory Steroids in the Prevention of Tooth Sensitivity
Clinical randomized, triple-blind, used to measure the level of tooth sensitivity on volunteers using a modified virtual analog scale (VAS).
- Trial name
- NCT02956070
- Testing
- Dexamethasone acetate, Potassium Nitrate
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Sensitivity, Tooth
Efficacy of a Desensitizing Agent During At-home Bleaching
The main objective of this study is to evaluate if the use of UltraEZ during at-home bleaching treatment is effective in reducing tooth sensitivity, as well as doesn't affect the degree of tooth bleaching.
- Trial name
- NCT06371092
- Testing
- UltraEZ
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Dentin Hypersensitivity
The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life
The aim of this study was to evaluate the effects of a self etch adhesive resin and two desensitizing agents(Calcium phosphate, 5% glutaraldehyde) in treatment of dentin hypersensitivity on the quality of life of individuals.
- Trial name
- NCT04887181
- Testing
- Teethmate Desensitizer, Gluma Desensitizer, Hybrid Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Dentin Hypersensitivity, Quality of Life
Validation of a French Version of the DHEQ
Dentin hypersensitivity (DH) results in brief, sharp pain in response to a stimulus. It often seems to be underdiagnosed but also undertreated due to the lack of consensus on the topic.
- Trial name
- DHEQ-VALID (NCT06466200)
- Testing
- Schiff Test, GOHAI questionnaire, OHIP questionnaire
- Where
- 3 sites in France
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Dentin Sensitivity
Clinical Evaluation of the Effectiveness of the Er:Cr:YSGG Laser in Reducing Dentin Sensitivity
This study aims to evaluate the clinical effectiveness of the Er:Cr laser in reducing dentin hypersensitivity (DH), a common dental condition characterized by sharp pain in response to thermal, mechanical, chemical, or osmotic…
- Trial name
- NCT06651827
- Testing
- Dentin sensitivity was measured using the Yeaple Probe and air stimulation tests before and after treatment
- Where
- Vietnam
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Allergic Rhinitis, Asthma in Children
Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
The aim of the study was to evaluate if there were differences in oral findings between patients diagnosed with allergic rhinitis and/or asthma and a control group of health people.
- Conditions
- Allergic Rhinitis, Asthma in Children, Dental Caries, Periodontal Diseases
- Trial name
- NCT05576142
- Testing
- Oral examination
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pavia