Clinical trials: Tendon Injury
Rotator Cuff Tears, Rotator Cuff Injuries
Comparison of Two Arthroscopic Rotator Cuff Repair Techniques: Knot-tying Versus Knotless Suture-bridge Technique
Suture-bridge technique has been widely used for rotator cuff tears with many studies showing superior clinical results and lower failure rates compared to other techniques.
- Trial name
- NCT03982108
- Testing
- Arthroscopic rotator cuff repair with knotless suture-bridge technique, Arthroscopic rotator cuff repair with knot-tying suture-bridge technique
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Koray Sahin
Rotator Cuff Tear
Epinephrine-Added Irrigation Versus Intravenous Tranexamic Acid in Arthroscopic Rotator Cuff Repair: A Prospective Randomized Controlled Trial
This single-center randomized controlled trial was designed to compare epinephrine-added irrigation fluid with an intravenous tranexamic acid (TXA) protocol during arthroscopic rotator cuff repair.
- Trial name
- NCT07442643
- Testing
- Epinephrine in irrigation fluid, Tranexamic acid, intravenous
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Rotator Cuff Tear
Rotator Cuff: Does the Vascularity Matter and the Role for PINPOINT
The overall goal of doing this study is to improve long term patient function and outcomes in the healing rates of Rotator Cuffs.
- Trial name
- NCT03001050
- Testing
- PINPOINT System
- Where
- United States
- Sponsor
- Nirav Amin, MD
Achilles Tendon, Ankle Sprain
Validity and Reliability of Calf Raise Tests in Patients With Achilles Tendon Rupture and Lateral Ankle Sprain
This study aims to evaluate the validity and reliability of clinically used Calf Raise Test parameters (collected with the "the Calf Raise App") between patients with Lateral Ankle Sprain or Achilles Tendon Repair and healthy…
- Trial name
- NCT07197593
- Testing
- Calf Raise Test
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Rotator Cuff Tears
Can Testosterone Accelerate Injury Recovery After Arthroscopic Rotator Cuff Repair
The objective of this study is to determine if treating patients undergoing arthroscopic rotator cuff repair with testosterone will allow patients to accelerate their recovery time after surgery.
- Trial name
- NCT04345666
- Testing
- Testosterone cypionate
- Where
- United States
- Sponsor
- Orthopedic Institute, Sioux Falls, SD
Rotator Cuff Tear
Trephination in Arthroscopic Cuff Repair: a Prospective Randomized Controlled
This Clinical Trial is being conducted to study an adjunctive treatment for rotator cuff repair; bone trephination."Trephination" is a procedure that involves making small perforations in the bone that the tendon is repaired…
- Trial name
- NCT01877772
- Testing
- Bone Trephination, Control
- Where
- Canada
- Volunteers
- 168 people
- Sponsor
- Ottawa Hospital Research Institute
ACL Injury
BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft
The overall objective of the proposed research is to conduct a prospective, randomized controlled trial to investigate whether the addition of BFR therapy to standard post-operative rehabilitation regimen significantly improves…
- Trial name
- NCT04519801
- Testing
- Blood Flow Restriction (BFR) therapy, Standard REHAB
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brooke Army Medical Center
Massive Rotator Cuff Tears, Rotator Cuff Injuries
Irreparable Rotator Cuff Tears Treatment. Comparison of Two Methods: With and Without Biceps Tendon Augmentation
Management of massive rotator cuff tears (MRCT) is associated with high rates of failure. The long head of the biceps tendon augmentation (LHBTA) by reinforcement of the reconstruction and additional blood supply may improve…
- Conditions
- Massive Rotator Cuff Tears, Rotator Cuff Injuries, Shoulder Pain Chronic
- Trial name
- NCT05001581
- Testing
- Arthroscopic partial repair of massive rotator cuff tear, Arthroscopic partial repair of rotator cuff with biceps augmentation
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Saint Lucas Hospital, Poland
Osteo Arthritis Shoulders, Osteonecrosis
Exactech Shoulder Post Market Clinical Follow-up Study
The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time.
- Conditions
- Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
- Trial name
- NCT05603728
- Where
- 40 sites in United States, Canada and 4 more
- Volunteers
- 20,000 people
- Sponsor
- Exactech
Tendinopathy
A Repeat Insult Patch Test (RIPT) Study Evaluating the Sensitization Potential of Topical SM04755 Solution in Healthy Volunteers
This is a single center, randomized, controlled, within subject comparison, single dose study to determine the sensitization potential of SM04755 solution on normal skin under semi-occlusive patch conditions.
- Trial name
- NCT03502434
- Testing
- SM04755, Vehicle, White Petrolatum
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Biosplice Therapeutics, Inc.
Rotator Cuff Injuries
Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears
The purpose of the study is to assess whether the REGENETEN™ Bioinductive Implant allows patients to get back to their everyday activities quicker than if the tendon is repaired by the standard repair technique 'Completion and…
- Trial name
- IMPACT (NCT05444465)
- Testing
- Isolated Bioinductive Repair, Completion and Repair
- Where
- 20 sites in United States, Australia and 4 more
- Volunteers
- 234 people
- Sponsor
- Smith & Nephew, Inc.
Chronic Pain, Osteoarthritis, Knee
Embo Registry; National Registry for Artery Embolization
Embo Registry is a retrospective and prospective observational study to evaluate real world effectiveness and the use of Artery Embolization as a treatment for chronic pain with patients that have osteoarthritis and localized…
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder
- Trial name
- NCT06477965
- Testing
- Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions of North Carolina
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Rotator Cuff Tear
Oxandrolone Rotator Cuff Trial
This study is about healing after a rotator cuff tear repair procedure. We hope to learn if a biologic medication: Oxandrolone, a synthetic derivative of the human hormone Testosterone (the principal male sex hormone and an…
- Trial name
- ORCT (NCT03091075)
- Testing
- Oxandrolone
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Southern California
Shoulder Dislocation
Results of Rotator Cuff Repair
The primary objective of this research is to examine the result of rotator cuff repairs following acute shoulder dislocations and to investigate whether timing of surgery following acute shoulder dislocations affects patients…
- Trial name
- NCT01549912
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Utah
Healthy
Study of the Optimal Number of Repetitions to Investigate the Cerebral Activity by fNIRS During a Voluntary Movement and an Illusory Movement Induced by Vibration
The purpose of this study is to investigate the cerebral activation of healthy participants during a voluntary movement and an illusory movement induced by vibration.
- Trial name
- MoViBloc (NCT07203807)
- Testing
- Voluntary movement and illusory movement of the right upper limb induced by TVS.
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Rotator Cuff Tear
Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique
This study is a single-blind, randomized study evaluating the 6 month and 2 year outcomes of patients treated with arthroscopic rotator cuff repair using one of two techniques.
- Trial name
- RCRPRFM (NCT02256891)
- Testing
- PRFM, Double Row
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Epicondylitis, Lateral
Arthroscopic Debridement Versus Autologous Cytokine Rich Serum for the Treatment of Lateral Epicondylitis
This study aims to compare arthroscopic resection (surgical intervention) versus infiltration of cytokine rich serum (CRS) (proteins derived from the patient's own blood) for the treatment of lateral epicondylitis (LE).
- Trial name
- DA-SARC (NCT04194710)
- Testing
- Autologous Cytokine Rich Serum, Arthroscopic Resection
- Where
- 2 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Corporacion Parc Tauli
Rotator Cuff Tear
Ultrasound to Predict the Prognosis of Rotator Cuff Tears
To predict the prognosis of large-to-massive RCTs and risk of re-tear by ultrasound elastography.
- Trial name
- NCT04601623
- Testing
- Sonoelastography
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Rotator Cuff Tears
The Effect of Self-rehabilitation Using Communication APP After Arthroscopic Surgery for Rotator Cuff Tear
The purpose of this study was to assess the clinical effect of a mobile application supporting home-based rehabilitation for the patients after arthroscopic rotator cuff repair.
- Trial name
- NCT05102968
- Testing
- Home-based rehabilitation supporting with the mobile application, Supervised rehabilitation by the therapist
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Veterans General Hospital.
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