Clinical trials: Teratozoospermia
Male Infertility, Oxidative Stress
Effect of Daily Intake of Gazpacho on Semen Quality and Oxidative Stress
The goal of this clinical trial is to learn whether drinking a daily serving of gazpacho can improve semen quality in men with reduced sperm quality.
- Conditions
- Male Infertility, Oxidative Stress, Subfertility, Oligozoospermia
- Trial name
- G-OXSEM (NCT07375238)
- Testing
- Standardized Mediterranean Diet, Gazpacho
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Ginefiv
Oligozoospermia, Asthenozoospermia
Effect of Walnuts on Sperm Parameters and Male Fertility
The investigators are testing the hypothesis that two ounces of whole-shelled walnuts/day added to the diet of men seeking care for infertility will beneficially affect sperm parameters and fertility.
- Conditions
- Oligozoospermia, Asthenozoospermia, Teratozoospermia, Fertility
- Trial name
- NCT01954498
- Testing
- Walnuts, OTC multivitamin
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Reproductive Issues, Male Infertility
Efficacy and Safety of a New Sperm Capacitation Method
Prospective, multicenter research study with a split-sample design on semen samples, without intervention, to evaluate the efficacy and safety of HyperSperm, a new sperm capacitation method, in 300 semen samples with various…
- Conditions
- Reproductive Issues, Male Infertility, Asthenozoospermia, Oligozoospermia
- Trial name
- HyperSperm01 (NCT06742437)
- Testing
- Standard sperm preparation, HyperSperm
- Where
- 4 sites in Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fecundis Lab SL
Teratozoospermia
Effect of Cannabis Consumption on Sperm Nuclear Quality in Infertile Men
Lifestyle and environmental factors can disrupt development and testicular function. In France, cannabis is the most widely used illicit substance and about 8% of adults between 18 and 64 years smoke cannabis at least once a…
- Trial name
- CANNASPERM (NCT02932527)
- Testing
- Questionnaire about cannabis consumption, blood intake, Semen samples collection
- Where
- 3 sites in France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Rouen
Male Infertility, Teratospermia
Live Birth Rate Between ICSI and AOA and ICSI Alone in Patients With Severe Teratospermia
The goal of this clinical trial is to compare the live birth rate between intracytoplasmic sperm injection (ICSI) and artificial oocyte activation (AOA) vs intracytoplasmic sperm injection alone in patients with teratospermia.
- Trial name
- NCT06561451
- Testing
- intracytoplasmic sperm injection and artificial oocyte activation, intracytoplasmic sperm injection
- Where
- China
- Volunteers
- 208 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Teratozoospermia
Medical Treatment Alone Versus Varicocelectomy Versus Varicocelectomy and Medical Treatment
A varicocele is defined as an abnormal venous dilatation and/or tortuosity of the pampiniform plexus in the scrotum. Although varicoceles are almost always and more common on the left side, up to 50% of the men with varicocele…
- Trial name
- NCT07016867
- Testing
- l-carnitine
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- South Valley University
Oligospermia, Teratospermia
Ramipril for the Treatment of Oligospermia
This is a randomized controlled trial to evaluate the effect of ramipril in stimulating and promoting sperm production in men with low sperm count.
- Conditions
- Oligospermia, Teratospermia, Asthenozoospermia, Male Infertility
- Trial name
- NCT01856361
- Testing
- Ramipril
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Spermatozoa, Abnormal, in Vitro Fertilization
The Influence of Sperm Morphology and Functional Indices on Blastocyst Development in Assisted Reproduction
Samples from male partners of 120 infertile couples undergoing IVF were analyzed. Sperm morphology was assessed using the SpermBlue staining method, while TZI, MAI, and SDI were calculated.
- Conditions
- Spermatozoa, Abnormal, in Vitro Fertilization, Blastocyst, Aneuploidy
- Trial name
- NCT06801652
- Testing
- Sperm morphology indexes
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Calla IVF Center
Infertility
Magnetic Nanoparticle Sperm Separation for Teratozoospermia Male and Women Older Than 35 Years
Women over 35 years old are likely to suffer from impaired oocyte repair capacity. Teratozoospermia is a condition reflects morphological affection of sperm. These spermatozoa would add an extra burden on the oocyte after ICSI.
- Trial name
- NCT03666364
- Testing
- Sperm preparation for ICSI
- Where
- 3 sites in Egypt
- Volunteers
- 1,400 people
- Sponsor
- Ibn Sina Hospital
Teratozoospermia, Sperm DNA Fragmentation
PGT-A Evaluates Advanced Sperm Selection in Embryos From High Teratozoospermia Males
In this study of 264 couples, sperm selection techniques in males with high teratozoospermia index and sperm DNA fragmentation significantly increased fertilization, blastocyst development rates, and maintained comparable embryo…
- Conditions
- Teratozoospermia, Sperm DNA Fragmentation, Infertility
- Trial name
- NCT06231589
- Testing
- Sperm Selection
- Where
- Egypt
- Volunteers
- 264 people
- Sponsor
- Ganin Fertility Center
Male Subfertility, Oligospermia
7 NUTS Study. Diet Modification and Male Fertility.
Setting. Outpatient fertility clinic. Aim. Investigate if a modification in nutritional habits may improve in the short term the qualities of human sperm, testing two hypothesis: i) that adding to the diet a natural whole food…
- Conditions
- Male Subfertility, Oligospermia, Asthenospermia, Teratospermia
- Trial name
- NCT02063256
- Testing
- 7 nuts a day, Diet modification
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Infertility, Male, Azoospermia
The Association of Gut Microbiota and Spermatogenic Dysfunction
This is a multicenter, case-control study that aims to investigate the relationship between microbiota and sperm quality via stool, blood, and urine microbiome, metabolomics, and collected clinical metadata.
- Conditions
- Infertility, Male, Azoospermia, Oligozoospermia, Asthenozoospermia
- Trial name
- NCT05628987
- Testing
- no intervention
- Where
- 3 sites in China
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Reduced Sperm Motility, IVF
Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods
Purpose: To compare the effects of the density gradient centrifugation and microfluidic chip sperm preparation methods on embryo development in a study population with astheno-teratozoospermia.
- Conditions
- Reduced Sperm Motility, IVF, ICSI, Astheno Teratozoospermia
- Trial name
- NCT04962074
- Testing
- Microfluidic sperm sorting chip, Density gradient
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Maltepe University
Male Infertility, Oligozoospermia
Probiotics on Sperm Quality in Male Infertility Patients
This randomized, placebo-controlled pilot study aims to evaluate the effects of probiotic supplementation on sperm quality in male patients diagnosed with infertility.
- Conditions
- Male Infertility, Oligozoospermia, Asthenozoospermia, Teratozoospermia
- Trial name
- NCT07345455
- Testing
- Probiotics
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Mackay Memorial Hospital
Oligospermia
A Clinical Study of Gulingji Capsule in the Treatment of Idiopathic Oligospermia, Asthenia, and Teratozoospermia
The object of study for patients with idiopathic disease of OAT, the use of multicenter, randomized, double-blind, controlled, prospective clinical research, choose according to row, standard units of idiopathic male infertility…
- Trial name
- NCT05320536
- Testing
- Guilingji Capsule
- Where
- 4 sites in China
- Volunteers
- 240 people
- Sponsor
- Jinling Hospital, China
Azoospermia, Nonobstructive, Teratospermia
Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product MediReg®
The study is open to patients with severe forms of male infertility (non-obstructive disorders of spermatogenesis, including azoospermia).
- Conditions
- Azoospermia, Nonobstructive, Teratospermia, Oligospermia, Men Infertility
- Trial name
- MARS (NCT06869863)
- Testing
- Medicinal product MediReg® (Human Mesenchymal Stromal Cell Secretome), lyophilizate for preparation of solution for injection in patients with severe spermatogenesis disorders, Clostilbegit (clomiphene) 50 mg 1 tablet x 1 p a day - 3 months, Triovit - 1 tablet x 1 p a day - 3 months, Folic acid - 1 tablet x 1 p a day - 3 months.
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Lomonosov Moscow State University Medical Research and Educational Center
Male Infertility
Administration of Antioxidants to Infertile Men and Sperm Quality
The purpose of this randomized clinical trial is to assess the effect of oral antioxidant administration to infertile men, by evaluating semen variables, sperm DFI and levels of ROS.
- Trial name
- NCT04256278
- Testing
- Spermotrend
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Aristotle University Of Thessaloniki