Clinical trials: Terminal Care
Clinical Decision-Making
Mixed Methods Study Web-based Life Support Decision Aid
Patients and families want to be involved in healthcare decisions. When the decision-making process does not engage older patients and their families, the care provided does not match patient preferences or meet their needs.
- Trial name
- eLSDA (NCT03271658)
- Testing
- Web based life support patient decision aid, Decision coaching
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Palliative Care
The PROAKTIV Study
The overall objective of this study is to identify whether the systematic anticipation of highly structured specialized palliative home care into primary care influences the quality of care and care utilization.
- Trial name
- NCT04673760
- Testing
- Specialized palliative home care
- Where
- Switzerland
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Aging Problems
Enhancing Care of the Aged and Dying in Prisons Ph II
The mission of corrections is to provide custody, control and care for incarcerated individuals. United States prisons are required by constitutional law to provide adequate care for growing numbers of older inmates who will…
- Trial name
- NCT03055429
- Testing
- Full Scale Unit
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Advance Care Planning
Culturally-Adapting a Communication Intervention to Improve Palliative Care Literacy on Two Native American Reservations
This study will evaluate the feasibility, acceptability, and perceived effectiveness of the culturally-adapted COMFORT Communication Curriculum in two Native American reservation communities.
- Trial name
- NCT03569150
- Testing
- Cultural adaptation/implementation COMFORT CC
- Volunteers
- healthy volunteers welcome
- Sponsor
- South Dakota State University
End-of-life Care
The Effect of End-of-Life Care Awareness Education on Knowledge, Attitudes, and Behaviors of Intensive Care Nurses: A Randomized Controlled Study
This study was designed as a prospective randomized controlled study in order to evaluate the effect of end-of-life care awareness training to be given to intensive care nurses on the knowledge levels, attitudes, and behaviors of…
- Trial name
- NCT05994430
- Testing
- End-of-life care awareness training in intensive care
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Istanbul University
End Stage Renal Disease, Decision Aid
A Guide to Conservative Care
This is a randomized pilot study to test the feasibility and acceptability of a patient decision aid on conservative care among older patients with advanced CKD and their close persons.
- Conditions
- End Stage Renal Disease, Decision Aid, Patient Engagement, Dialysis
- Trial name
- NCT04919941
- Testing
- A Guide to Conservative Care
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections
Family Centered Advanced Care Planning for Adolescents With HIV/AIDS and Their Families
This study will examine the efficacy of Family Centered Advance Care Planning in enhancing quality of life, integrating effective end-of-life care, and preventing depression and anxiety among HIV infected adolescents and their…
- Trial name
- NCT00723476
- Testing
- Family Centered Advanced Care Planning (FCACP) sessions, Health education control sessions
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Maureen Lyon
Advance Care Planning, Advance Directives
Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations
Compared to the general population, individuals from underserved communities are more likely to receive low quality end-of-life care and unwanted, costly and burdensome treatments due in part to a lack of advance care planning…
- Conditions
- Advance Care Planning, Advance Directives, Terminal Illness, Chronic Illness
- Trial name
- NCT04612738
- Testing
- Hello (serious game), The Conversation Project (CP) Starter Kit, Table Topics (general conversation game)
- Where
- 79 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Healthy
Intervention to Improve Expression of End of Life Preferences for Homeless Persons
The purpose of this study is to determine whether homeless individuals will complete a living will and whether guidance enhances rates of completion and to see whether filling out a living will has any impact on the care given at…
- Trial name
- SELPH (NCT00546884)
- Testing
- MI condition, GI
- Where
- 2 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Death Anxiety, Death Attitude (Implicit/Explicit)
Platform for End-of-life Awareness, Conversations, and Education (PEACE) Among Registered Nurses
The goal of this clinical trial is to evaluate whether the PEACE program can improve early career registered nurses' registered nurses' attitudes towards caring for palliative patients, ability to cope with patients' death, and…
- Conditions
- Death Anxiety, Death Attitude (Implicit/Explicit), End of Life Care, Advanced Care Planning (ACP)
- Trial name
- NCT07774468
- Testing
- Death Conversation, Online ACP Education
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
The Families or Next of Kin of Patients Treated at MSKCC for Non-cutaneous Squamous Cell Carcinomas of the, Upper Aerodigestive Tract
Improving End of Life Care in Head and Neck Cancer
The purpose of this study is to improve the quality of care provided for head and neck cancer patients. By better understanding the end of life experiences of dying patients and their families, the investigators hope to better…
- Trial name
- NCT01632969
- Testing
- The The Family Assessment of Treatment at the End of life (FATE ) survey
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
End of Life Care, Cancer
Serious Illness Communication Project
The purpose of the study is to evaluate the impact of implementing a "Serious Illness Conversation Guide" to guide patient/family-clinician discussions and planning about end-of-life care decisions.
- Trial name
- NCT01786811
- Testing
- Training
- Where
- United States
- Volunteers
- 994 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Influenza
Trial of the Safety, Transmissibility, and Phenotypic and Genotypic Stability of Influenza Virus Vaccine,(CAIV-T), in Children Who Attend Day Care. (Final Report Version 2.0)
To assess whether CAIV-T was transmitted from vaccinated children to their unvaccinated contacts in a day care setting; and if so, to estimate the rate of transmission.
- Trial name
- NCT00192361
- Testing
- CAIV-T
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Advance Care Planning
Advance Care Planning With Formerly Homeless Older Adults Residing in Permanent Supportive Housing
The homeless population is aging, with an increasing proportion of individuals over age 50 who experience accelerated aging, high rates of mortality, and a high risk of not having their wishes honored at the end of life.
- Trial name
- ACP-PSH (NCT06239896)
- Testing
- Facilitated Group ACP Session, Facilitated one-on-one ACP visits
- Where
- 6 sites in United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Terminal Illness, Critical Illness
Targeting Bias to Reduce Disparities in End of Life Care
This study aims to determine the ways in which clinician implicit racial biases affect clinician communication with family members of patients near the end of life and to test a novel physician training intervention to reduce the…
- Trial name
- BRiDgE-Sim (NCT05165888)
- Testing
- Communication and Bias Mitigation Training, Communication skills training
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Self-Efficacy, Attitude
End-of-Life Care Preparedness Program for Senior Nursing Students
In this study, between 1 April- 31 May 2025, who met the inclusion and exclusion criteria, a total of 59 senior nursing students who are with 4th year nursing students starting the Nursing Department of Çankırı Karatekin…
- Conditions
- Self-Efficacy, Attitude, End-of-Life Care
- Trial name
- NCT07257159
- Testing
- The End-of-Life Care Preparedness Program
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Hilal ALTUNDAL DURU
Hypertension, Chronic Kidney Disease
Genetic Testing to Understand and Address Renal Disease Disparities
In this genomic medicine implementation pilot project, the investigators aim to conduct a randomized trial in a network of community health centers and primary care facilities to study processes, effects and challenges of…
- Conditions
- Hypertension, Chronic Kidney Disease, Genomics
- Trial name
- GUARDD (NCT02234063)
- Testing
- Immediate Genetic Testing
- Where
- 2 sites in United States
- Volunteers
- 2,052 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
End Stage Disease
Comparison Between the Assessment of Anxious and Depressive Symptomology
In palliative care, anxiety and depression in advanced cancer are under evaluated, under diagnosed and therefore under treated. 5 to 30% of patients present anxious and depressive disorders. Physical symptoms are easy to assess.
- Trial name
- EDAPAL (NCT04148924)
- Testing
- Questionnaire, Medical staff questionnaire
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Death Attitude (Implicit/Explicit), Death Anxiety
Die-logue Program for Community Dwelling Adults: A Randomized Controlled Trial
The goal of this clinical trial is to evaluate whether the Die-logue program can improve attitudes toward death, coping with death, and readiness for advance care planning (ACP) among community-dwelling middle-aged adults aged…
- Conditions
- Death Attitude (Implicit/Explicit), Death Anxiety, End of Life Care, Advanced Care Planning (ACP)
- Trial name
- NCT07525492
- Testing
- Death Conversation, Online ACP Education
- Where
- Singapore
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- National University of Singapore