Clinical trials: Testosterone
Female Sexual Dysfunction, Anorgasmia
Clitoral Location in Relation to Sexual Function Using Pelvic Imaging
Women who are unable to achieve orgasm compared to women who have normal orgasmic function may have different clitoral anatomy and different hormone levels.
- Trial name
- NCT01195701
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Testosterone Deficiency
Pharmacokinetic Evaluation of Serum Testosterone Concentrations After Administration of Clomiphene Citrate
This is a randomized, open-label trial examining two doses of clomiphene citrate in men with low serum testosterone concentrations (total testosterone (TT) < 300 ng/dl).
- Trial name
- NCT05096169
- Testing
- Clomiphene Citrate 25mg, Clomiphene Citrate 50mg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Major Depressive Disorder, Anxiety Disorders
Sensitivity of Short and Long Allele Carriers of the 5-HTTLPR to Environmental Threat Post Hydrocortisone Administration
The current study will test the causal relationship between elevated levels of cortisol and the serotonin transporter gene (5-HTTLPR) as these factors influence sensitivity to environmental threat.
- Trial name
- 5-HTTLPR (NCT01710202)
- Testing
- Hydrocortisone
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Hypertension
Testosterone Regulation of the Natriuretic Peptide System
The proposed study is a physiologic investigation of the effects of testosterone on the natriuretic peptide system. The hypotheses of the study are that testosterone administration will decrease natriuretic peptide levels and…
- Trial name
- NCT02269072
- Testing
- Testosterone, Nesiritide, Leuprolide
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypogonadism, Diabetes
Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial.
Background: Men≥65 years often produce lower levels of testosterone, meaning there is less testosterone circulating to the tissues of the body.
- Conditions
- Hypogonadism, Diabetes, Sarcopenia, Osteoporosis
- Trial name
- NCT00104572
- Testing
- Androgel (Testosterone Gel), Anastrozole (Aromatase Inhibitor), Calcium Cardone 500mg with vitamin D 400 IU
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Men With Low Testosterone Levels
Study to Determine the Effects of Testosterone Replacement Therapy in Aging Men With Androgen Deficiency
The T-001 study is a placebo-controlled investigation of the effects of injectable testosterone replacement therapy on prostate tissues of aging men with low testosterone levels.
- Trial name
- NCT00161304
- Testing
- Testosterone Enanthate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Leonard S. Marks, M.D.
Hypogonadism
Vitamin D Treatment and Hypogonadism in Men
Low total testosterone (TT) is present in about 30% of men aged >60 years and in up to 7% of younger men. Male hypogonadism is associated with metabolic and cardiovascular diseases as well as with increased mortality.
- Trial name
- NCT01748370
- Testing
- Vitamin D supplementation in hypogonadal men, Vitamin D supplementation in eugonadal men
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Healthy, Men
Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception
The long term objective is to develop a gel to be used as a male contraceptive.
- Conditions
- Healthy, Men, Male Contraception
- Trial name
- NCT03452111
- Testing
- Nestorone + Testosterone Combination Gel
- Where
- 17 sites in United States, Chile and 5 more
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Premier Research
Muscle Anabolism
A Study to Evaluate the Effect of Testosterone on Muscle Fractional Synthetic Rate (MK-0000-064)
This is a study to evaluate the use of fractional synthetic rate as an early biomarker of muscle anabolism (muscle build-up).
- Trial name
- NCT00816712
- Testing
- Comparator: Testosterone 300 mg, intramuscular injection, Comparator: Testosterone 100 mg, Intramuscular injection
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy Volunteers
Study of Exposure to Substances Prohibited by the World Anti-Doping Agency in Healthy Volunteers.
Background: The use of stimulants such as bupropion, enzyme inhibitors such as anastrozole, androgens such as testosterone, antigonadotropins such as danazol, and diuretics such as chlorthalidone have been reported in urine drug…
- Trial name
- ESPAMA (NCT04757532)
- Testing
- Bupropion, Anastrozole, Testosterone cyclopentylpropionate
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Female Hormone Profile
Acute Vitamin D Supplementation on Testosterone in Females
Participation will take place over two visits to the Clinical Exercise Research Center (CERC) at the University of Southern California Health Sciences Campus.
- Trial name
- NCT06610968
- Testing
- Vitamin D (Cholecalciferol )
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Major Depression
Testosterone and Major Depression
Context - As men age, testosterone levels decline leading to symptoms that overlap with the symptoms of major depression. Little is known about the potential role of testosterone in the treatment of major depression.Objective …
- Trial name
- NCT00286546
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto