Clinical trials: Therapeutic Endoscopy
Colorectal Cancer, Colonic Adenoma
Bowel Cleansing Performance of the Pure-Vu System in Patients With a History of Poor Bowel Preparation
The diagnostic accuracy and safety of colonoscopy highly depends on the quality of the pre-procedural bowel preparation. A past history of poor bowel preparation is the most important risk factor of inadequate bowel cleansing at…
- Conditions
- Colorectal Cancer, Colonic Adenoma, Bowel Preparation
- Trial name
- NCT04700410
- Testing
- Pure-Vu System
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 44 people
- Sponsor
- Radboud University Medical Center
Biliary Obstruction, Complication of Treatment
Treatment of Postsphincterotomy Bleeding With a Novel Self-assembling Peptide Hemostatic Gel.
The aim of this observational study is to evaluate safety and efficacy of a novel self-assembling peptide hemostatic gel in reduction of bleeding after endoscopic sphincterotomy during ERCP (endoscopic retrograde…
- Trial name
- ERCPURA (NCT05886127)
- Testing
- A novel hemostatic agent (Purastat®)
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- General University Hospital, Prague
Renal Cell Carcinoma
Endoscopic Robot-Assisted Simple Enucleation Versus Standard Robot-Assisted Partial Nephrectomy in the Treatment of T1 Renal Cell Carcinoma
This is a non-inferiority, randomized controlled trial to compare the peri-operative, renal functional and oncologic outcomes of endoscopic robot-assisted simple enucleation(ERASE) and standard robot-assisted partial…
- Trial name
- NCT03624673
- Testing
- endoscopic robot-assisted simple enucleation, standard robot-assisted partial nephrectomy
- Where
- China
- Volunteers
- 380 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Peptic Ulcer Hemorrhage
Role of Doppler Ultrasound in Severe Peptic Ulcer Hemorrhage
The aim of study is to evaluate whether Doppler ultrasound can accurately identify patients who are at risk of recurrent bleeding, who will require endoscopic therapy, and who will fail endoscopic therapy.
- Trial name
- NCT00164905
- Testing
- Doppler ultrasound probe
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Chinese University of Hong Kong
Peptic Ulcer, Bleeding
TAE and Surgery in Patients With Peptic Ulcer Bleeding Uncontrolled by Endoscopic Therapy
The aim of the study is to compare the outcomes of trans-catheter arterial embolization (TAE) and surgery as salvage therapy of peptic ulcer bleeding after failed endoscopic therapy.
- Trial name
- NCT00766961
- Testing
- Trans-catheter arterial embolization, Surgery
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Chinese University of Hong Kong
Barretts Esophagus With Dysplasia, Intramucosal Adenocarcinoma
Utility Of Mutational Load As A Predictor For Endoscopic Treatment Response In Barrett's Esophagus
To evaluate association between mutational load (ML) from esophageal biopsy specimens in pre-endoscopic eradication therapy (EET) in Barrett's Esophagus (BE) or Intramucosal adenocarcinoma (IMC) patients and treatment resistance…
- Trial name
- NCT04316975
- Testing
- Study Driven Procurement of Biopsies
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of North Carolina, Chapel Hill
Pharyngo-oesphageal Strictures
Balloon Dilation Under Portable X-ray System in the Treatment of Pharyngo-oesphageal Strictures
The aim of our study is to evaluate the outcomes (efficacy and safety) and to present our experience in X-DR portable x-ray system guided endoscopic balloon dilatation in the treatment of pharyngo-oesophageal strictures as an…
- Trial name
- NCT06846801
- Testing
- Balloon Dilation Under Portable X-ray System
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Mohammed Elrabie Ahmed
Erosive Esophagitis
Efficacy and Safety of Vonoprazan Compared to Lansoprazole in the Maintenance Treatment of Erosive Esophagitis
This is a comparative study of vonoprazan (TAK-438) (10 mg or 20 mg) in participants in whom endoscopic healing of erosive esophagitis has been confirmed with vonoprazan or adequate treatment with a proton pump inhibitor (PPI)…
- Trial name
- NCT02388737
- Testing
- Vonoprazan, Lansoprazole
- Where
- 72 sites in China, Malaysia and 2 more
- Volunteers
- 703 people
- Sponsor
- Takeda
Subglottic Stenosis
Endoscopic Mucosal Injection Versus Ultrasound-Guided Injection of Triamcinolone to Treat Subglottic Stenosis
This study employs a multicenter, randomized controlled trial method, where patients meeting the inclusion criteria for subglottic stenosis are randomly divided into two groups.
- Trial name
- NCT06275269
- Testing
- Ultrasound-Guided, Translaryngeal Endoscopic Mucosal Injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- China-Japan Friendship Hospital
Polyps, Colon Cancer
Endoscopic Full Thickness Resection Versus Standard Therapy of the Colorectal Neoplasia
Most of the cancers develop from the adenomatous polyps. The therapeutic methods have been established already - endoscopic polypectomy (EPE) for stalked polyps and endoscopic mucosal resection (EMR) or endoscopic submucosal…
- Trial name
- NCT03868605
- Testing
- EMR and ESD, Over- the- scope full- thickness resection device
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Military University Hospital, Prague
Gastroparesis
Per-oral Endoscopy Pyloromyotomy (G-POEM) in the Treatment of Refractory Diabetic Gastroparesis : Prospective Evaluation of Efficacy
The objective of the study is to document the clinical efficacy and complications of endoscopic pyloromyotomy in patients with refractory gastroparesis (diabetic, post-operative and idiopathic), compared to Botulinic toxin…
- Trial name
- G-POEM (NCT02927886)
- Testing
- Per-oral endoscopy pyloromyotomy, Intrapyloric injection of Botulinum toxin
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Barrett's Esophagus
High Definition White Light Endoscopy and Narrow Band Imaging for the Assessment of Barrett's Disease After Endoscopic Therapy
The investigators seek to test the hypothesis that the improved version of high definition white light endoscopes and Narrow Band Imaging (NBI) are more accurate in detecting residual Barrett's Metaplasia and Dysplasia disease…
- Trial name
- NCT01360801
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chirurgical Intervention, Auriculotherapy
Adjuvant Treatment of Postoperative Pain Following Endoscopic Carpal Tunnel Surgery by Auriculotherapy
Retrospective study on the effect of auriculotherapy on postoperative pain after carpal tunnel surgery
- Trial name
- AURDO1 (NCT06693167)
- Testing
- chirurgie canal carpien
- Volunteers
- 38 people
- Sponsor
- Clinique Bizet
BPH
Global Post-Market Registry Using Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue
The purpose of this study is to evaluate the efficacy of the AQUABEAM System for the treatment of Lower Urinary Tract Symptoms (LUTS) resulting from Benign Prostatic Hyperplasia (BPH).
- Trial name
- OPEN WATER (NCT02974751)
- Testing
- Aquablation
- Where
- 5 sites in Australia, Germany and 3 more
- Volunteers
- 178 people
- Sponsor
- PROCEPT BioRobotics
Gastrointestinal Fistula, Gastrointestinal Perforation
Endoscopic Treatment of Intestinal Fistulas and Perforations
Gastrointestinal leaks or perforations are currently treated through either open or laparoscopic surgical procedures. The purpose of this research is to determine whether new endoscopic tools are safe and effective in the…
- Trial name
- NCT01303653
- Testing
- endoscopic closure of gastrointestinal fistulas and perforations
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Oregon Clinic
Obesity, Primary
A Feasibility Study for the Treatment of Primary Obesity Cross-over Arm
Cross-over arm of the pilot study evaluating a treatment for obesity.
- Trial name
- NCT05939973
- Testing
- g-Cath EZ Delivery Catheter with Snowshoe Suture Anchors
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- USGI Medical
Choledocholithiasis
Treatment of Choledocolithiasis by Laparoscopic Exploration
There are three treatment options for choledocholithiasis: endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy; laparoscopic exploration of the main bile duct with concomitant…
- Trial name
- NCT04690101
- Testing
- none, this is an observational study
- Volunteers
- 75 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Barretts Esophagus With Dysplasia
Impact of Histologic Concordance Between Biopsies and the Endoscopic Resection Specimen, in the Treatment of Barrett's Esophagus in Dysplasia, on the Recurrence of Dysplasia
Influence of histological concordance on the risk of recurrence: the histological concordance being the comparison between the biopsies and the endoscopic resection piece and its concordant response rate.
- Trial name
- PatheBarett (NCT03685799)
- Testing
- Pathological revision
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Institut Paoli-Calmettes
Common Bile Duct Gallstones, Choledocholithiasis
Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla
This study compare 2 techniques to treat difficult bile duct stones endoscopically
- Trial name
- EHL (NCT02703077)
- Testing
- Spyglass, Balloon dilation of the papilla, EHL (electrohydraulic lithotripsy)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Liver Cirrhosis, Esophageal and Gastric Varices
A Randomized Controlled Study on the Treatment of Cirrhosis Combined With Hypersplenism
The purpose of this study was to compare the effects of partial splenic artery embolization combined with endoscopic treatment and endoscopic treatment alone on portal hypertension in cirrhosis with hyperplenism or splenomegaly…
- Conditions
- Liver Cirrhosis, Esophageal and Gastric Varices, Hypersplenism
- Trial name
- NCT05055713
- Testing
- Endoscopic therapy+ beta blockers, Endoscopic therapy+ PSE+beta blockers, Endoscopic therapy
- Where
- China
- Volunteers
- 368 people
- Sponsor
- Qilu Hospital of Shandong University