Clinical trials: Therapeutic Endoscopy
Obesity, Obesity, Morbid
Endoscopic Metabolic and Bariatric Therapies
This is a prospective collection of data from adult patients who have had an endoscopic metabolic and bariatric endoscopy procedure (EMBT) for primary or revision surgical procedures for obesity.
- Conditions
- Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate
- Trial name
- EMBTs (NCT05725967)
- Testing
- Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Christopher C. Thompson, MD, MSc
GERD
STRETTA ,Radio Frequency Ablation (RFA) v/s Sham Therapy for the Treatment of Refractory GERD
Gastro-esophageal reflux disease (GERD) is a chronic disorder with significant impact on the quality of life of patients. It may also lead to several complications like peptic strictures, ulcerations, Barrett 's disease and…
- Trial name
- STRETTAGERD (NCT02935881)
- Testing
- Radio Frequency Ablation (RFA) (Stretta Procedure)
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Asian Institute of Gastroenterology, India
Urinary Calculi
Endoscopic Combined Intrarenal Surgery vs. Percutaneous Nephrolithotomy for Treatment of Staghorn Calculi
This is a prospective randomized study to compare endoscopic combined intrarenal surgery and PCNL as modalities of treatment for staghorn stones. In terms of efficacy and safety
- Trial name
- NCT06519812
- Testing
- Combined Intrarenal Surgery and percutaneous nephrolithotomy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Pancreatic Cancer
Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic Lesions
This is a 7-year prospective single-center registry study to assess the safety and efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the treatment of pancreatic lesions.
- Trial name
- NCT07737171
- Testing
- Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center, Houston
Ulcerative Colitis
Study of Effects and of Modifications in Apoptosis Regulators Observed After Stopping 5-ASA Treatment in Patients With Inactive Ulcerative Colitis
Male or female, 18 years of age or older. Ulcerative Colitis described according usual criteria, diagnosed for at least 1 year. Oral maintenance treatment with 5-aminosalicylic acid (5-ASA) only for at least 3 months with a…
- Trial name
- NCT00209287
- Testing
- Observe patients with inactive ulcerative colitis
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Ferring Pharmaceuticals
Head and Neck Cancer, Esophageal Cancer Stage
Outcomes of A Novel Treatment Decision of Patients With Esophageal and Head and Neck Carcinoma Synchronously
To summarise the outcomes of a treatment decision of patients with superficial esophageal carcinoma synchronously associated with head and neck cancer, that is endoscopic treatment for the superficial esophageal carcinoma plus…
- Trial name
- NCT03450447
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Yanqing Li
Gallbladder Diseases, Cholecystitis, Acute
Endoscopic vs Non-endoscopic Drainage for Benign Gallbladder Diseases in High-risk Patients or Patients Desiring Gallbladder Preservation
Common gallbladder conditions like gallstones, polyps, and gallbladder inflammation are typically treated by surgically removing the gallbladder.
- Conditions
- Gallbladder Diseases, Cholecystitis, Acute, Cholelithiasis
- Trial name
- GB-PRESERVE (NCT07649811)
- Testing
- Endoscopic Gallbladder Drainage, Percutaneous Gallbladder Drainage
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Air Force Military Medical University, China
Gastroesophageal Reflux
Treatment Of Gastroesophageal Reflux Disease By Endoscopic Fundoplication, A Placebo-Controlled Study
Aim: To evaluate the therapeutic efficacy of a therapeutic procedure, involving endoscopic suturing, for gastroesophageal reflux disease (GERD) compared to a sham procedure.
- Trial name
- NCT00235677
- Testing
- Endoscopic gastroplication
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- UMC Utrecht
Acute Appendicitis
Clinical Trial Comparing ERAT vs Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis
Endoscopic retrograde appendicitis therapy (ERAT) is a new and minimally invasive method for the diagnosis and treatment of acute appendicitis.After a positive diagnosis of acute appendicitis is established by either colonoscopic…
- Trial name
- NCT02789865
- Testing
- Ertapenem, Levofloxacin and Metronidazole, Endoscopic retrograde appendicitis therapy (ERAT), Appendectomy
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Hemorrhage, Anemia
Capsule Endoscopy Versus Conservative Therapy for Obscure Gastrointestinal Bleeding
This study is a single center prospective randomized control trial comparing the utility of performing capsule endoscopy compared to conservative management with oral iron therapy as the initial course of action in patients with…
- Trial name
- NCT01837030
- Testing
- Ferrous sulfate, Capsule Endoscopy
- Where
- United States
- Sponsor
- Medical University of South Carolina
Zenker Diverticulum
Evaluation of Endoscopic Treatment of Zenker's Diverticulum Using LigaSure
The primary objective of this study is to evaluation the success of endoscopic treatment of Zenker's diverticulum using a LigaSure device (thermal fusion of vessels) via a measure of swallowing function at 12 months post-surgery.
- Trial name
- ZENKER LS (NCT01739426)
- Testing
- Repair w/LigaSure
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Craniosynostosis
Endoscopic Treatment for Isolated, Single Suture Craniosynostosis
This is a prospective study to evaluate outcomes in patients undergoing endoscopic craniectomy for isolated, single-suture craniosynostosis.
- Trial name
- NCT00769847
- Testing
- Endoscopic strip craniectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Colorectal Cancer
Simulation Training of Endoscopy Staff to Improve Patient Experience in Colonoscopy
Some patients experience a degree of pain and discomfort during endoscopic examination of the large bowel. Sedatives and analgesics may be administered in low doses.
- Trial name
- NCT02428907
- Testing
- simulation training
- Where
- Denmark
- Volunteers
- 539 people
- Sponsor
- Aalborg University Hospital
Barrett Esophagus, Adenocarcinoma Esophagus
Outcomes of Endoscopically Resected High-risk Mucosal and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's Esophagus
The purpose of this study is to assess lymph node metastasis rate, distant metastasis rate, disease-specific mortality, and overall mortality in patients with Barrett's related T1b and high risk T1a esophageal adenocarcinoma…
- Conditions
- Barrett Esophagus, Adenocarcinoma Esophagus, Submucosal Esophageal Adenocarcinoma, High-risk Mucosal Esophageal Adenocarcinoma
- Trial name
- NCT04818476
- Testing
- diagnostic endoscopic resection
- Where
- 16 sites in Australia, Belgium and 5 more
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hydrocephalus
HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants
Hydrocephalus is a potentially debilitating neurological condition that primarily affects babies under a year of age and has traditionally been treated by inserting a shunt between the brain and the abdomen.
- Trial name
- ESTHI (NCT04177914)
- Testing
- Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization (ETV+CPC), Ventriculoperitoneal Shunt
- Where
- 21 sites in United States, Canada
- Volunteers
- 165 people
- Sponsor
- University of Utah
Hypoxia, Obesity
High-flow Nasal Oxygen Therapy in Obese Patients Undergoing Sedativegastrointestinal Endoscopy
Obese patients often have fat accumulation in the head and neck, increased soft tissue in the oropharynx, decreased lung compliance, decreased lung volume and residual volume, and some obese patients also suffer from obstructive…
- Conditions
- Hypoxia, Obesity, Gastrostomy
- Trial name
- NCT06585306
- Testing
- jaw lift, increasing oxygen flow, mask ventilation, intubation
- Where
- China
- Volunteers
- 864 people
- Sponsor
- XiaoLiang Wang
Gastroduodenal Ulceration
Evaluation of Upper GI Ulceration Induced by PL2200 Versus Aspirin in At-Risk Subjects
This trial is a Phase 2, randomized, controlled study to compare the degree of mucosal injury after the oral administration of an investigational product, PL2200, and a marketed 325 mg immediate-release aspirin product.
- Trial name
- NCT01646814
- Testing
- PL2200, Aspirin tablets
- Where
- 10 sites in United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- PLx Pharma
Gastrointestinal Bleeding, Antiplatelet Therapy
MCE Identifying Bleeding Lesions in Patients with Antiplatelet Drugs-Related Acute Non-Hematochezia Gastrointestinal Bleeding
The goal of this clinical trial is to explore the diagnostic efficacy of detachable string magnetically controlled capsule endoscopy (ds-MCE) for identification of bleeding lesions in patients with antiplatelet drugs-related…
- Trial name
- MCE (NCT06698874)
- Testing
- ds-MCE and EGD examinations
- Where
- 4 sites in China
- Volunteers
- 204 people
- Sponsor
- Changhai Hospital
Acute Pancreatitis (AP), Gallstone Pancreatitis
Pentoxifylline Treatment in Acute Pancreatitis (AP)
The purpose of this study was to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis.
- Conditions
- Acute Pancreatitis (AP), Gallstone Pancreatitis, Alcoholic Pancreatitis, Trauma Acute Pancreatitis
- Trial name
- AP (NCT02487225)
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Mayo Clinic
Colon Cancer
Endoscopic Therapy Or Surgery for Early Colon Cancer
The trial is a randomized head-to-head comparison of the benefits, harms and burdens of endoscopic full-thickness resection (eFTR), a novel, minimally invasive endoscopic treatment modality, for early colon cancer as compared to…
- Trial name
- ETHOS (NCT06940947)
- Testing
- eFTR, Surgery
- Where
- Poland
- Volunteers
- 434 people
- Sponsor
- Norwegian Department of Health and Social Affairs