Clinical trials: Therapeutic Engagement
Opioid Use Disorder, Chronic Pain
Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial
This study is a multisite randomized clinical trial of a treatment designed to reduce pain interference while simultaneously addressing relapse prevention among individuals who have co-occurring chronic pain and Opioid Use…
- Trial name
- HOPE (NCT05571917)
- Testing
- Acceptance and Commitment Therapy + Mindfulness Based Relapse Prevention (ACT + MBRP), Enhance Usual Care (EUC)
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- University of New Mexico
Opioid-use Disorder
Medication Maintenance Therapy in Community Pharmacy Settings
The goal of this study is to examine how the pharmacy can better optimize treatment expansion by providing pharmacy-based medication assisted treatment (MAT) for maintenance under a collaborative pharmacy practice agreement.
- Trial name
- MATPharm (NCT03766893)
- Testing
- Buprenorphine / Naloxone Oral Product, injectable naltrexone, Pharmacy maintenance addiction care
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Lifespan
Social Wellness Through Engagement in a Creative Process, Patient Engagement
The ARTS-REHAB Project Research Study
The ARTS-REHAB Project Research Study examines how meaningful engagement in a creative process might impact inpatients in rehabilitation centres.
- Trial name
- ARTS-REHAB (NCT02374658)
- Testing
- Living Through the Arts Intervetion
- Where
- Canada
- Volunteers
- 188 people
- Sponsor
- The Royal Conservatory of Music
Patient Adherence, HIV Positive
CCTG 594: Engagement and Retention in Care for HIV+
CCTG 594 is a controlled, unblinded, two-arm, randomized (1:1) clinical trial to evaluate the effectiveness of a clinic-based HIV ALERT specialist on improving endpoints of retention in care and maintenance of ART as compared to…
- Trial name
- NCT01957748
- Testing
- SoC + ALERT Intervention
- Where
- 3 sites in United States
- Volunteers
- 117 people
- Sponsor
- University of California, San Diego
PTSD, Depression Disorders
Patient Engagement in PTSD Treatment (PEP)
The goal of this clinical study is to improve the outcome of outpatient PTSD treatment at two clinics treating majority ethnic Danes and refugees with PTSD respectively.
- Conditions
- PTSD, Depression Disorders, Patient Engagement
- Trial name
- PEP (NCT06755710)
- Testing
- Introductory PTSD module, Shared Decision Making, Treatment as Usual
- Where
- Denmark
- Volunteers
- 427 people
- Sponsor
- Herlev and Gentofte Hospital
Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases
Culturally Tailored HPV Psychoeducational Multimedia Intervention
Community members ages 18 - 45 years old from the El Paso, Texas, U.S.-Mexico Border Region will be recruited to compare psychoeducational multimedia interventions focused on the human papillomavirus (HPV).
- Conditions
- Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases, Intention, Adherence, Patient
- Trial name
- NCT06098690
- Testing
- Culturally Tailored Multimedia Psychoeducational HPV Intervention, General HPV Multimedia Psychoeducational Control Group
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Patient Empowerment, Patient Engagement
Video Extradition of Continuous Positive Airway Pressure - Influence on Compliance
Confirming or denying it in the future is an opportunity for certain patient groups to have the option of video delivery. So that in calm circumstances and possibly.
- Conditions
- Patient Empowerment, Patient Engagement, Patient Compliance
- Trial name
- NCT04249518
- Testing
- Videoeducation
- Volunteers
- 1,234 people
- Sponsor
- University of Aarhus
Musculoskeletal Pain - Acute and Subacute Conditions
MOVE Protocol - Movement-Oriented Velocity of Engagement
A Prospective, Multi-Site, Interventional Case-Series Evaluating the MOVE (Movement-Oriented Velocity of Engagement) Protocol for Musculoskeletal Pain Recovery
- Trial name
- NCT07220200
- Testing
- MOVE Rehabilitation Protocol
- Where
- 4 sites in United States, India
- Volunteers
- 52 people
- Sponsor
- MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Tobacco Dependence Caused by Cigarettes
Feasibility and Acceptability of Switching to E-cigarettes Among Cigarette Smokers Engaged in SUD Treatment
The purpose of the proposed study is to examine the feasibility of integrating a smoking harm reduction program featuring provision of e-cigarettes and tailored instructions to switch into an existing substance use disorder…
- Trial name
- NCT05918887
- Testing
- NJOY ACE commercial e-cigarette
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Nevada, Reno
Cataract, Refractive Errors
Strengthening Community- to- Hospital Eye Care Pathways From Boko Eye Care Center in Rural Assam
This operational research project aims to strengthen continuity of eye care delivery between community screening and hospital-based treatment in rural Assam by redesigning referral pathways from the Boko Eye Care Center (ECC) to…
- Trial name
- NCT07333248
- Testing
- Experimental: Integrated Referral and Engagement Model
- Where
- India
- Volunteers
- 2,000 people
- Sponsor
- Seva Canada Society
Rare Disorders
Implementing Dynamic Consent for Rare Disease Patients
The study aims to test on a cohort of rare patients a digital innovative tool to support patients/parents in the informed consent and assent process and to keep up-to-date a lawful informed and dynamic consent and to use samples…
- Trial name
- ConsDinamico (NCT06656247)
- Testing
- Online consenting
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Human Immunodeficiency Virus, Treatment Adherence
Data Science and Qualitative Research for Decision Support in the HIV Care Cascade
The goal of this study is to determine whether clinical prediction algorithms derived using statistical machine learning methods can be used to improve patient outcomes in large HIV care programs in sub-Saharan Africa and…
- Conditions
- Human Immunodeficiency Virus, Treatment Adherence, Treatment Compliance, Patient No Show
- Trial name
- CASCADE (NCT06604663)
- Testing
- Activation of the CDSS system
- Where
- Kenya
- Volunteers
- 80,000 people
- Sponsor
- Brown University
Obesity
The EMBER Trial for Weight Management Engagement
This study will test whether EMBER, a self-help tool to increase weight loss treatment engagement, helps veterans engage in Veterans Health Administration (VHA) weight management programs.
- Trial name
- NCT05424081
- Testing
- EMBER, Control
- Where
- 2 sites in United States
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
GBAT+Individual, GBAT+Engagement Booster
Transdiagnostic Group Therapy (GBAT) for Autistic Adults With Personalized Therapeutics
The purpose of this study is to build upon an earlier study that evaluated the use of a 10-week transdiagnostic Group Behavioral Activation Therapy (GBAT), a telehealth delivered intervention, as a cost effective and accessible…
- Conditions
- GBAT+Individual, GBAT+Engagement Booster, GBAT+Both
- Trial name
- (GBAT+) (NCT05512221)
- Testing
- GBAT+I, GBAT+E - Phase I, Watchful Waiting and Groups - Phase 2, GBAT+IE
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Rutgers, The State University of New Jersey
Healthy, Digital Health
Personalized NFTs as a Trial Participation Incentive
NFTs are blockchain-based digital and physical assets traded on digital marketplaces. Current and exploratory NFT use cases include art, collectibles, in-game items, real estate, ticketing, events, fintech, licenses, IDs, and…
- Conditions
- Healthy, Digital Health, Incentive Interventions
- Trial name
- AvatarDTx (NCT06647030)
- Testing
- CURATE.DTx sessions, Interview
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Institute for Digital Medicine (WisDM)
HIV Infection
Use of Incentives to Retain Drug Users in HIV Therapy
In many urban centres including Vancouver's Downtown Eastside, there is a high rate of HIV infection among users of illicit drugs.
- Trial name
- Incentives-2 (NCT01488942)
- Testing
- monetary reinforcer
- Where
- Canada
- Volunteers
- 139 people
- Sponsor
- University of British Columbia
Multiple Chronic Conditions, Patient Engagement
AI-Augmented Motivational Interviewing Training for Primary Care
This study will examine the impact of training primary care providers (PCPs) in motivational interviewing (MI) using artificial intelligence (AI) to augment the training process.
- Conditions
- Multiple Chronic Conditions, Patient Engagement, Burnout, Professional, Motivational Interviewing
- Trial name
- AIM-PC (NCT06597123)
- Testing
- Basic AI (artificial intelligence)-Augmented Motivational Interviewing Training, Plus AI (artificial intelligence)-Augmented Motivational Interviewing Training
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Wright State University
Decision Making, Computer-assisted
Diagnosis Assessment With Diaana #3
Single-center, unblinded, 2:1 parallel pseudo-randomized efficacy trial. In the intervention group only, resident physicians will be assisted by the automated medical history-taking device "Diaana" during their consultations in…
- Conditions
- Decision Making, Computer-assisted, General Practitioners, Patient Engagement
- Trial name
- NCT03939650
- Testing
- Diaana
- Where
- Switzerland
- Sponsor
- Adrien Schwitzguebel
Substance Use Disorder, Opioid Use Disorder, Moderate
EXHIT ENTRE Comparative Effectiveness Trial
This study is a multi-site open-label randomized comparative effectiveness trial of a 28-day formulation of extended-release buprenorphine (XR-BUP) versus treatment as usual (TAU) for hospitalized patients with a moderate or…
- Conditions
- Substance Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
- Trial name
- EXHITENTRE (NCT04345718)
- Testing
- Extended Release Buprenorphine, Treatment as Usual
- Where
- 6 sites in United States
- Volunteers
- 344 people
- Sponsor
- Gavin Bart
Tobacco-Related Carcinoma, Smoking &Amp; Tobacco Cessation
Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation
This phase IV clinical trial determines the impact of implementing a Quitline electronic (e)Referral system with an enhanced academic detailing implementation strategy on Quitline reach, tobacco cessation assistance and…
- Trial name
- CONNECT (NCT04969978)
- Testing
- Enhanced Academic Detailing, Informational Intervention
- Where
- United States
- Volunteers
- 9,133 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute