Clinical trials: Therapy Effect
Brain Insulin Sensitivity, Healthy Controls
Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect?
This study aimed at helping researchers understand how a medication called haloperidol can affect insulin action in the brain. Insulin is a hormone in the body that controls sugar levels in part by lowering the amount of glucose…
- Conditions
- Brain Insulin Sensitivity, Healthy Controls, Cognition
- Trial name
- NCT07109245
- Testing
- Haloperidol, Insulin Lispro, Saline
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Mechanical Ventilation
Tracheal Suctioning and Expiratory Pause in Bronchial Hygiene
A randomized crossover clinical trial conducted in an Intensive Care Unit of the Hospital de Clinicas de Porto Alegre (HCPA) to compare the efficacy of the two techniques on the amount of aspirated pulmonary secretion and…
- Trial name
- NCT05579145
- Testing
- 5-Second Expiratory Pause, 10-Second Expiratory Pause
- Where
- 2 sites in Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cicatrix, Post-Surgical Complication
Class I Medical Device on Post-surgical Scars
To compare the effect of a class I pullulan based medical device containing Allium cepa \& HA versus a class I medical device silicone gel on new post-surgical wounds
- Conditions
- Cicatrix, Post-Surgical Complication, Scar Itching, Keloid
- Trial name
- NCT05412745
- Testing
- Kaloidon Plus, silicone gel
- Where
- 2 sites in Italy
- Volunteers
- 64 people
- Sponsor
- University of Rome Tor Vergata
Dialysis Amyloidosis, Hypotension
Studying the Effect of Dialysate Temperature on Toxin Removal and Hypotension
Hemodialysis (HD) is widely used treatment for end stage renal diseases (ESRD) patients. The chief aims of HD are solute and fluid removal.
- Trial name
- NCT02064153
- Testing
- Cool dialysate, Warm dialysate
- Where
- Singapore
- Volunteers
- 14 people
- Sponsor
- National University Hospital, Singapore
Traumatic Brain Injury, Depression
The Effect of Exercise on Mood After Traumatic Brain Injury
We proposed to examine the effect of an aerobic exercise intervention on depression in persons with Traumatic Brain Injury (TBI).
- Trial name
- NCT00571545
- Testing
- Aerobic exercise, No exercise
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Washington
the Effect of Virtual Reality on Stroke Rehabilitation
Effect of Robotic Therapy on Upper Extremity With Stroke
The purpose of this study is to determine how adding virtual reality assisted robotic treatment to traditional rehabilitation affects stroke patients' pain levels, functional status, and daily living activities.After conventional…
- Trial name
- NCT05815823
- Testing
- robotic exercise therapy, conventional therapy
- Volunteers
- 40 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Allergic Rhinitis
The Effects of Using Yupingfeng Powder with Variation for the Treatment of Allergic Rhinitis
Allergic rhinitis (AR) is an IgE mediated chronic inflammatory disease of the upper airways characterized by symptoms of sneezing, rhinorrhea, nasal itching, and nasal obstruction .
- Trial name
- NCT04976023
- Testing
- Yupingfeng Powder granules
- Where
- Hong Kong
- Volunteers
- 58 people
- Sponsor
- Prof. Lin Zhixiu
tDCS, Cues Type
tDCS and the Gaze Cueing Effect
This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.
- Conditions
- tDCS, Cues Type, SOA, Congruency
- Trial name
- NCT07592559
- Testing
- Gaze cues, Arrow cues, SOA 200 ms
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Healthy
Pain Inhibitory Effects of a Single Painful Mechanical Stimulus Compared to Multiple and Multiple at Different Locations
The objective is to estimate the effects on pain thresholds of a single painful mechanical stimulus compared to multiple and multiple stimuli at different locations.
- Trial name
- NCT05730179
- Testing
- Mechanical Conditioning stimulus
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Josue Fernandez Carnero
Covid19, Cytokine Storm
Intramuscular Effect of Polymerized Type I Collagen on the Cytokine Storm in COVID-19 Patients
SARS-CoV-2 infection induces a hyperinflammatory syndrome, causing the acute respiratory distress syndrome, massive lung cell destruction and, as a plausible sequelae, pulmonary fibrosis in COVID-19 patients.
- Conditions
- Covid19, Cytokine Storm, Regulation of Inflammatory Response, Pulmonary Fibrosis
- Trial name
- NCT04517162
- Testing
- Collagen-Polyvinylpyrrolidone
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Janette Furuzawa Carballeda
Pelvic Examination,Virtual Reality
Examining the Effect of Virtual Reality on Pain and Anxiety Management During Pelvic Examination
Objective: The study was conducted as a randomized controlled experimental study to examine the effect of the video watched with virtual reality glasses during the pelvic examination on the level of pain and anxiety perceived by…
- Trial name
- NCT05545488
- Testing
- Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
Effect of Intervention to Improve Stroke Recognition
Despite the abundance of stroke education materials available, studies continue to reveal severe deficiencies in stroke literacy (knowledge of symptoms, urgent action, and prevention measures).
- Trial name
- NCT01497886
- Testing
- Hip Hop Stroke educational program, Nutrition Education program
- Where
- United States
- Volunteers
- 4,614 people
- Sponsor
- Columbia University
HIV Infections, Obesity
Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain
The purpose of this research study is to understand why certain HIV medication regimens (called anti-retroviral or ARV medications) cause more weight gain than others.
- Trial name
- NCT05463783
- Testing
- Biktarvy, Symtuza
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- East Carolina University
Pulmonary Disease, Chronic Obstructive
The Effect of Spa Treatment on Chronic Obstructive Pulmonary Disease
The primary objective of this study is to measure and compare the number of exacerbations (moderate or severe) between the two groups of randomized patients with and without thermal treatment).
- Trial name
- BPCeaux (NCT01296854)
- Testing
- Spa therapy
- Where
- 6 sites in France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Postoperative Pain
Effect of Intravenous Acetaminophen on Postoperative Opioid-related Complications
Some patients have respiratory depression (decreased breaths per minute) after surgery. Acetaminophen, an FDA approved pain medication, may prevent this problem.
- Trial name
- NCT02156154
- Testing
- Intravenous Acetaminophen
- Where
- United States
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Post-Concussion Symptoms, Distorted; Balance
Comparing the Effect of Osteopathic Manipulative Medicine (OMM) Versus Counseling in the Treatment of Concussion
Concussion or mild traumatic brain injury (TBI) is a challenging injury for physicians to manage and is among the most serious disabling neurological disorders.
- Trial name
- NCT02750566
- Testing
- Osteopathic Manipulative Treatment, Counseling
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- New York Institute of Technology
Aged
Factors Affecting Kinesiophobia in the Elderly
In epidemiological studies, the incidence of foot problems has been found to be high as a result of the increase in life expectancy.
- Trial name
- NCT06138366
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Cerebral Palsy (CP), Cerebral Palsy, Hemiplegic
Effect of Whirlpool Therapy Combined With Botulinum Toxin in Children With Cerebral Palsy
This study aims to investigate the effects of adding whirlpool therapy to standard rehabilitation in children with cerebral palsy who recently received botulinum toxin-A injections.
- Trial name
- NCT07690722
- Testing
- Conventional Rehabilitation, Whirlpool Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Ankara Etlik City Hospital
Biliary Tract Neoplasms
The Effect of Individualized Precision Therapy Programs in Patients With BTC
This is a prospective cohort study. Patients who meet the inclusion criteria will be enrolled in this study. The samples of biliary tract tumors will be collected.
- Trial name
- NCT02943031
- Testing
- Individualized Precision Therapy Programs
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Cardiovascular Diseases
Randomized Controlled Trial on Uptake of NHS Health Checks
The National Health Service (NHS) Health Check is a significant part of the strategy to tackle premature mortality and promote healthy lifestyles.
- Trial name
- NCT03524131
- Testing
- risk-framed leaflet, benefits-framed leaflet, current national leaflet
- Where
- United Kingdom
- Volunteers
- 12,000 people
- Sponsor
- Public Health England
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