Clinical trials: Thin-cap fIbroatheroma
Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques
Effectiveness of Interventional Therapy for Non-Flow-Limiting Vulnerable Plaques
The aim of this clinical trial is to explore the optimal preventative treatment strategy for non-flow-limiting vulnerable plaques.
- Conditions
- Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques, Thin-cap fIbroatheroma, Acute Coronary Syndromes (ACS)
- Trial name
- NCT06855537
- Testing
- PCI strategy, OMT strategy
- Where
- China
- Volunteers
- 2,190 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease, Thin-cap fIbroatheroma
The Efficacy of Alirocumab for Thin-cap fIbroatheroma in Patients With Coronary Artery Disease Estimated by Optical Coherence Tomography
the purpose of this study is to show that alirocumab with statin therapy have a s tronger stabilizing effect on vulnerable plaque in coronary artery disease than statin alone administration
- Trial name
- ALTAIR (NCT03552432)
- Testing
- Alirocumab
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Kobe University
Coronary Artery Disease, Obstructive Sleep Apnea
Relationship Between Obstructive Sleep Apnea and Coronary Atherosclerosis
Obstructive sleep apnea (OSA) is a respiratory disorder of sleep characterized by recurrent episodes of complete or partial upper airway obstruction, leading to intermittent oxygen deprivation.
- Trial name
- IDEAS-OSA (NCT01306526)
- Where
- Singapore
- Volunteers
- 118 people
- Sponsor
- National University of Singapore
Atherosclerosis Coronary Artery With Angina Pectoris, Atheroscleroses, Coronary
First-In-Human Intracoronary OCT-FLIm In Patients Undergoing PCI
Patients will undergo intracoronary imaging using combined optical coherence tomography-fluorescence lifetime imaging (OCT-FLIm) during percutaneous coronary intervention, and the obtained imaging data will be used to assess the…
- Conditions
- Atherosclerosis Coronary Artery With Angina Pectoris, Atheroscleroses, Coronary, Atherosclerotic Plaque, Thin-cap fIbroatheroma
- Trial name
- NCT04835467
- Testing
- Dual-modal OCT-FLIm
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University Guro Hospital
Acute Coronary Syndrome
Endothelial Dysfunction and Plaque Vulnerability
Thinning of fibrous cap in atherosclerotic plaques is associated with plaque vulnerability. The high resolution of optical coherence tomography (OCT) provides an accurate measurement of fibrous cap thickness.
- Trial name
- NCT01578616
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Yokohama City University Medical Center
Coronary Artery Disease
Ezetimibe and Atorvastatin Therapy on TCFA
After successful coronary angiography and OCT examination, patients with TCFAs in non-culprit, mild-to-moderate stenotic lesions will be enrolled.
- Trial name
- NCT02588235
- Testing
- Ezetimibe and Atorvastatin, Atorvastatin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital