Clinical trials: Third Molar
Tooth Extraction
Remimazolam vs Midazolam Cognitive and Motor Recovery After Intravenous Conscious Sedation for Dental Extractions.
The study is looking to see if a new drug (remimazolam) that is used to sedate and relax adults (aged 18-59 years) having dental treatment is better than the current drug in use (midozolam).
- Trial name
- REMIDENT (NCT05220462)
- Testing
- Remimazolam, Midazolam
- Where
- United Kingdom
- Volunteers
- 128 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pain, Postoperative
Extraction of Distoangular and Vertically Positioned Mandibular 3rd Molars
Mandibular 3rd molars are the most commonly impacted teeth in oral cavity followed by maxillary 3rd molars and maxillary canines respectively.
- Trial name
- NCT05032989
- Testing
- Extraction of mandibular 3rd molar via Cowhorn forcep technique, Extraction of mandibular 3rd molar via conventional technique
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dental Anxiety, Hemodynamic
Anxiety and Hemodynamic Changes in Third Molar Extraction After Patient Education
This randomized clinical trial investigates the effect of different preoperative patient information strategies on anxiety levels and hemodynamic responses during third molar extraction.
- Conditions
- Dental Anxiety, Hemodynamic, Molar, Third, Tooth Extraction
- Trial name
- NCT07018115
- Testing
- Basic Preoperative Information, Detailed Verbal Preoperative Information, Visual Preoperative Information (2D Animation)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Ummugulsum Coskun
Impacted Third Molar Tooth
Impact of Antibiotic Treatment and Extraction on the Oral Micro Biome
This is a prospective, longitudinal, observational, cohort study investigating young adults undergoing surgical extraction of a wisdom tooth with and without antibiotics post-operatively.
- Trial name
- NCT02951676
- Testing
- Extraction
- Where
- China
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mandible Fracture
Forensic Dental Age Estimation : Validation of Computed Tomography for Third Molar Demirjian's Staging
Age can be estimated in different ways by using skeletal age and dental age. Currently, bone age is determine thanks to the wrist x-rayed, and the dental age using variation in mineralization (Demirjian's score) on the dental…
- Trial name
- SCAO (NCT04907552)
- Where
- France
- Volunteers
- 557 people
- Sponsor
- University Hospital, Montpellier
Teeth; Lesion, Tooth Diseases
Low-Dose CBCT Protocol for Pre-Surgical Evaluation of the Mandibular Third Molar, a Feasible Choice?
Low-Dose CBCT Protocol for Pre-Surgical Evaluation of the Mandibular Third Molar. CBCT investigations with standard and low dose protocol for evalutation of the mandibular third molar.
- Trial name
- NCT05519462
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Malmö University
Postoperative Morbidity, Trauma
Fruit And Vegetables and OUtcomes After Removal of Impacted TEeth
The proposed study will test the following hypotheses: 1. Pre-operative daily dual supplementation with Juice Plus+ (fruit \& vegetable) for 11 weeks will result in reduced post-operative morbidity in terms of quality of life…
- Conditions
- Postoperative Morbidity, Trauma, Wound Healing
- Trial name
- FAVOURITE (NCT01145820)
- Testing
- Juice plus
- Where
- United Kingdom
- Volunteers
- 246 people
- Sponsor
- University of Birmingham
Trismus, Edema
Low Laser Light Therapy After Impacted Third Molar Removal
Third molars extraction is a surgery frequently performed in dentistry. It is generally associated to a great postoperative distress rendered by pain, swelling and trismus, caused by surgical trauma inflammation.
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT02602431
- Testing
- Extra-oral laser irradiation, Intra-oral laser irradiation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Edema Face, Scanning Devices
Lidar-based Scanning of Fascial Edema (FE)
This study compared handheld and mechanically assisted scanning to evaluate fascial edema after third molar extraction. The flexible ruler served as the reference.
- Trial name
- FE (NCT07690488)
- Testing
- Measurement with flexible ruler, Measurement with handheld scanning, Measurement with mechanically assisted scanning
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ege University
Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction
Autogenous Tooth Bone Graft for Alveolar Socket Preservation
The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction.
- Conditions
- Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction, Tooth Extraction Site Healing
- Trial name
- ATBG (NCT07267637)
- Testing
- "Autogenous Tooth Bone Graft"
- Where
- Yemen
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haifaa Mohammed Al-hussini
Wisdom Tooth, Socket Preservation
Soft and Hard Tissue Healing Following Alveolar Ridge Preservation of Mandibular Third Molar Extraction Socket Filled With Auto Tooth Bone Graft or Alloplastic Graft
This study compared two bone graft materials: 1. Auto Tooth Bone (ATB) (made from the patient's own extracted tooth) and 2. EthOss® a synthetic alternative.
- Trial name
- AutoToothGraft (NCT07723183)
- Testing
- auto tooth graft material
- Where
- Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pain Management, Shared Decision Making
ACE Pilot 3: Decision Aid 2 Options vs 3 Options
This research protocol is exploring a behavioral intervention: shared decision making with the use of a decision aid to select a post-operative analgesic.
- Trial name
- NCT07011472
- Testing
- Decision-Aid with 2-options, Decision aid with 3 options
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Drug Effect, Tooth Extraction
Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia
In the complexity of the Dental care the third molar surgery is one of the most common procedures, it is indicated for multiple reasons like infections in root canal, prosthetics or even esthetical purposes.
- Trial name
- ECA (NCT04166890)
- Testing
- Articaine / EPINEPHrine Cartridge
- Where
- Colombia
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Impacted Third Molar Tooth
EFFICACY OF ICE PACK THERAPY AFTER IMPACTED THIRD MOLAR SURGERY
this study evaluates the effect of cold application after impacted third molar extractions. Patients have bilateral impacted third molar tooth included in this study.
- Trial name
- NCT03261869
- Testing
- Cold application
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Baskent University
Impacted Third Molar Tooth
Effect of Honey and Dexamethason on Extraction Healing
Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated
- Trial name
- NCT04848259
- Testing
- Normal saline, Dexamethasone, Honey
- Where
- Saudi Arabia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Third Molars Extraction, Low Level Laser Therapy
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure.
- Conditions
- Third Molars Extraction, Low Level Laser Therapy, Bone Healing
- Trial name
- NCT07190950
- Testing
- Low Level Laser Therapy
- Where
- Vietnam
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Third Molar Surgery
Intraosseous Versus Submucosal Dexamethsone Injection in Third Molar Surgery
The goal of this clinical trial is to learn if intraosseous dexamethasone injection is better for pain and swelling postop 3rd molar surgery than submucosal dexamethasone injection.
- Trial name
- NCT06720051
- Testing
- Intraosseous dexamethasone injection after 3rd molar surgery, Submucosal dexamethasone injection after 3rd molar surgery
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Trigemino-Cardiac Reflex, Impacted Third Molar Tooth
The Frequency of Trigeminocardiac Reflex During the Extraction of Impacted Mandibular Wisdom Teeth
The goal of this clinical trial is to investigate trigeminocardiac reflex (TCR) formation during surgical extraction of mandibular impacted wisdom teeth in healthy adults.
- Trial name
- NCT06499532
- Testing
- Monitoring and Surgical removal of mandibular impacted wisdom teeth, using Gow-Gates anesthesia technique, Monitoring and Surgical removal of mandibular impacted wisdom teeth, using inferior alveolar nerve block anesthesia technique
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Pain, Postoperative
Potential Benefit of the Combination of Metamizole and Ibuprofen After Third Lower Molar Extraction
Postoperative pain is common and particularly outpatients may experience unsatisfactory pain relief. This randomized, double-blind, crossover study of postoperative pain in outpatients undergoing split-mouth, third lower molar…
- Trial name
- NovIbu (NCT02686021)
- Testing
- Metamizole and Ibuprofen
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University Hospital, Basel, Switzerland
Facial Pain, Temporomandibular Joint Disorder
Diagnosis and Evaluation of Patients Needing Third Molar (Wisdom Tooth) Extraction and Patients With Chronic Facial Pain
This study provides a mechanism for evaluating patients for possible participation in NIDCR clinical research studies. NIDCR studies involve three major areas-pain, neurosensory mechanisms, and pain-relieving drugs-all of which…
- Trial name
- NCT00001600
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)