Clinical trials: Third Molar Extraction Surgery, open to volunteers
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Gel in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07520097)
- Testing
- Concentrated Growth Factor (CGF) Gel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Pain, Molar
A Study of LY4515100 in Participants With Pain Following Third Molar Removal
The purpose of this study is to evaluate the safety and efficacy of LY4515100 and see how a single oral dose compares with placebo in acute postsurgical pain after removing impacted third molars.
- Conditions
- Acute Pain, Molar, Molar, Third, Surgery, Oral
- Trial name
- NCT07511816
- Testing
- LY4515100
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Eli Lilly and Company
Impacted Third Molar Tooth
Local Metformin Gel and Impacted Lower Third Molar
Completed medical and dental history will take for all patients and the position of the impacted teeth will evaluate by panoramic films.
- Trial name
- NCT06975839
- Testing
- Metformin, non metformin gel
- Volunteers
- 36 people
- Sponsor
- Fayoum University
Impacted Mandibular Third Molar
Comparison of Electrocautery and Scalpel Blade Incisions of Impacted Mandibular Third Molars
This randomized controlled trial aims to compare electrocautery and scalpel blade incisions during surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07723326
- Testing
- scalpel blade incision, electrocautery incision
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Riphah International University
Pain (Visceral, Somatic, or Neuropathic)
Postoperative Pain and Swelling After Flap vsFlapless Technique For Mandibular Third Molar Surgery
This randomized controlled trial evaluates postoperative pain and facial swelling following surgical removal of partially impacted mandibular third molars using flap versus flapless techniques.
- Trial name
- NCT07247929
- Testing
- flap technqiue for mandibular third molar extraction Arm A, flapless technquie arm b
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Dental Anxiety, Mandibular Third Molar
Virtual Reality to Reduce Anxiety in Adults Having Lower Wisdom Tooth Surgery
This randomized controlled trial will evaluate whether immersive virtual reality can reduce anxiety in adults undergoing surgical removal of mandibular third molars under local anesthesia.
- Trial name
- NCT07853014
- Testing
- Immersive Virtual Reality (Meta Quest 3)
- Where
- Vietnam
- Volunteers
- 120 people
- Sponsor
- Hanoi Medical University
Wisdom Tooth Removal, Post Operative Complications
Comparing Methylprednisolone And Hyaluronic Acid To Reduce Wisdom Tooth Surgery Complications
The goal of this clinical trial is to assess and compare the effectiveness of methylprednisolone and hyaluronic acid (HA), alone and in combination, in managing post-operative complications following the surgical extraction of…
- Conditions
- Wisdom Tooth Removal, Post Operative Complications, Hyaluronic Acid, Methylprednisolone
- Trial name
- NCT07317596
- Testing
- Methyl Prednisolone (MP), Hyaluronic Acid (HA)
- Where
- Yemen
- Volunteers
- 40 people
- Sponsor
- Sana'a University
Trismus, Edema
Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care
The surgical removal of impacted lower wisdom teeth (mandibular third molars) frequently leads to uncomfortable postoperative symptoms, including pain, facial swelling (edema), and restricted jaw movement (trismus).
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT07719270
- Testing
- Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Alveolar Bone Loss
Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge…
- Trial name
- NCT06457373
- Testing
- Demineralized Dentin Allograft, Demineralized Dentin Autograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Horus University
Third Molars Extraction, Oral Health-Related Quality of Life
Effects of Irrigation Solutions at Different Temperatures Used in Mandibular Third Molar Surgery
The present study aims to compare the effects of saline, chlorhexidine, and hydrogen peroxide irrigation solutions at different temperatures on postoperative complications, including pain, swelling, and mouth opening, as well as…
- Conditions
- Third Molars Extraction, Oral Health-Related Quality of Life, Postoperative Complications in Maxillofacial Surgery, Irrigation Solution
- Trial name
- NCT07835958
- Testing
- 4°C sterile saline solution, 25°C sterile saline solution, 4°C 0.2% chlorhexidine solution
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Oral Health
Effect of Hypochlorous Acid-containing Mouthwash on Healing After Impacted Wisdom Tooth Surgery
INTRODUCTION: Local chemotherapeutic agents are used to reduce inflammation after impacted tooth extraction and to minimize possible complications, as well as to increase patient comfort.
- Trial name
- Mouthwash (NCT06920485)
- Testing
- Third molar surgery, Pain Medicine, Wound healing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluation of the Use of CGF Based Sticky Bone Packed in Fresh Odontectomy Site of Impacted Lower 3rd Molars
This clinical study aims to evaluate the effectiveness of Concentrated Growth Factor (CGF)-based sticky bone in enhancing bone healing after surgical removal of impacted mandibular third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07517835)
- Testing
- Concentrated growth factors
- Volunteers
- 10 people
- Sponsor
- Cairo University
Psychological Stress
Presurgical Illustration and Psychological Stress in Mandibular Third Molar Surgery
The aim of this clinical trial is to evaluate the influence of presurgical patient's diagrammatic illustration of mandibular third molar (Wisdom tooth) surgery on degrees of psychological stress.
- Trial name
- NCT07803510
- Testing
- Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Third Molar Impaction, Surgical Extraction of Impacted Third Molars
The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar
Surgical extraction of impacted third molar is the most common surgical procedure performed in oral and maxillofacial surgery. The immediate post operative complications after 3rd molar surgery are pain, swelling and trismus…
- Trial name
- NCT07351279
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- University of Health Sciences Lahore
Postoperative Pain, Postoperative Complications
Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction
The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars.
- Conditions
- Postoperative Pain, Postoperative Complications, Trismus, Periodontal Health
- Trial name
- NCT07180498
- Testing
- Chlorhexidine Gluconate 0.12% Mouthwash, Tea Tree Oil mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Harran University
Post Operative Swelling
Assessment of Post Operative Swelling Among Patients Following Extraction of Impacted Third Molars
This randomized controlled trial aims to compare Ward's incision and Comma incision regarding postoperative swelling following extraction of impacted mandibular third molars.
- Trial name
- APOSTM (NCT07655089)
- Testing
- Ward's Incision, Comma Incision
- Volunteers
- 116 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Alveolar Bone Loss, Periodontal Pocket
Regenerative Gel (Emdogain®) for Healing After Wisdom Tooth Extraction
This study investigates whether the intraoperative application of a specialized regenerative gel (Emdogain®) can improve the periodontal health of the mandibular second molar by preventing or reducing the formation of tissue…
- Conditions
- Alveolar Bone Loss, Periodontal Pocket, Impacted Tooth With Abnormal Positioning
- Trial name
- NCT07718932
- Testing
- Enamel Matrix Derivative (Emdogain®)
- Where
- 2 sites in Greece
- Volunteers
- 70 people
- Sponsor
- Aristotle University Of Thessaloniki
Dental Anxiety, Third Molar Extraction
Clinical Study Evaluating the Effect of Virtual Reality on Reducing Patients' Anxiety During Wisdom Teeth Extraction
Dental anxiety is common during third molar extractions and may exacerbate pain perception. Local anesthesia does not prevent exposure to stress-inducing stimuli.
- Conditions
- Dental Anxiety, Third Molar Extraction, Oral Surgery
- Trial name
- SEREIN (NCT07273968)
- Testing
- Virtual reality HypnoVR® (VR headset + hypnotic software), Control Group (No VR)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France