Clinical trials: Third Molar Surgery
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Impacted Mandibular Third Molar Extraction
Piezo-surgery Technique and Intramuscular Dexamethasone Injection to Reduce Postoperative Pain After Impacted Mandibular Third Molar Surgery
The purpose of my study is to test the effect of using piezosurgery and dexamethasone injection in the surgical extraction of impacted mandibular third molars, on Postoperative Pain.
- Trial name
- NCT04889781
- Testing
- Dexamethasone injection, Piezosurgery, Conventional Rotatory instruments
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Military Healthcare - Oral and Maxillofacial Surgery Department
Anesthesia
VR Sedation in Third Molar Surgery
Anaesthesia or sedation for dental surgery is Challenging. Over-sedation, leading to upper airway obstruction, desaturation and apnoea, is very common.
- Trial name
- NCT04540666
- Testing
- Propofol
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Facial Swelling, Tooth Position Anomalies
Effect of Pre-emptive Dose of Prednisone Versus Placebo in Impacted Third Molar Surgery
The present study proposes to compare the effect of a single preoperative dose of prednisone versus placebo in terms of facial swelling, trismus and pain after surgical removal of the mandibular third molar (M3M) in a split-mouth…
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT05830747
- Testing
- Prednisone
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Psychological Stress
Presurgical Illustration and Psychological Stress in Mandibular Third Molar Surgery
The aim of this clinical trial is to evaluate the influence of presurgical patient's diagrammatic illustration of mandibular third molar (Wisdom tooth) surgery on degrees of psychological stress.
- Trial name
- NCT07803510
- Testing
- Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Swelling, Trismus
Comparing Different Suturing Techniques on the Post-operative Morbidity After Removal of Impacted Mandibular Third Molar
This study compares the effect of two types of suturing techniques in the postoperative swelling and mouth opening after surgical removal of impacted mandibular third molar.
- Trial name
- NCT03492814
- Testing
- partial wound closure, total wound closure
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Impacted Mandibular Third Molar
Comparison of Chlorhexidine and Hypochlorous Acid Mouthwash After Impacted Third Molar Surgery
Impacted mandibular third molar extraction is one of the most common procedures in oral and maxillofacial surgery and is frequently associated with postoperative complications such as pain, edema, and trismus, which may…
- Trial name
- NCT07466992
- Testing
- Hypochlorous Acid, Chlorhexidine Gluconate Mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Pain, Other Surgical Procedures
Comparison of the Clinical Efficacy of Ketoprofen, Associated or Not With Omeprazole in Lower Third Molar Removal
The control of pain, swelling and trismus in patients undergoing oral and maxillofacial surgery is frequently performed through the administration of non-steroidal anti-inflammatory drugs (NSAIDS).
- Trial name
- NCT02730026
- Testing
- Ketoprofen, Ketoprofen and Omeprazole
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Luis Fernando Simoneti
Oral Soft Tissue Conditions
Phytotherapy Agent in Third Molar Surgery
The aim of the present study was to evaluate the effect of a phytotherapy agent on clinical and inflammatory parameters, for the postoperative therapy of the impacted third molar surgery.
- Trial name
- NCT03335683
- Testing
- Lenidase
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gaetano Isola, DDS, PhD
Alveolar Bone Loss
Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge…
- Trial name
- NCT06457373
- Testing
- Demineralized Dentin Allograft, Demineralized Dentin Autograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Horus University
Impacted Wisdom Tooth, Pain
Investigation of Effectiveness of Local Antibiotic With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo
The aim of this study was investigate the effectiveness of Local Antibiotic Applications With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo and In Vitro.
- Conditions
- Impacted Wisdom Tooth, Pain, Staphylococcus Aureus
- Trial name
- NCT05678296
- Testing
- Diagnosis, Analgesic, traditional osteotomies
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ceren Melahat Donmezer
Third Molars Extraction, Oral Health-Related Quality of Life
Effects of Irrigation Solutions at Different Temperatures Used in Mandibular Third Molar Surgery
The present study aims to compare the effects of saline, chlorhexidine, and hydrogen peroxide irrigation solutions at different temperatures on postoperative complications, including pain, swelling, and mouth opening, as well as…
- Conditions
- Third Molars Extraction, Oral Health-Related Quality of Life, Postoperative Complications in Maxillofacial Surgery, Irrigation Solution
- Trial name
- NCT07835958
- Testing
- 4°C sterile saline solution, 25°C sterile saline solution, 4°C 0.2% chlorhexidine solution
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pain, Acute, Edema
Lornoxicam Versus Etodolac After Third Molar Surgery
Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction
- Conditions
- Pain, Acute, Edema, Trismus
- Trial name
- NCT05679453
- Testing
- Lornoxicam 8 Mg Oral Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Pain, Oral Surgery
Hyaluronic Acid and Amino Acid Gel Applied to the Alveolar Socket After Mandibular Third Molar Extraction
Objective: The study aimed to assess the effect of topical application of an amino acid + sodium hyaluronate acid gel after lower third molar extraction.
- Conditions
- Pain, Oral Surgery, Third Molar Extraction
- Trial name
- NCT03428698
- Testing
- Aminogam
- Where
- Italy
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Oral Health Care
The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery
Introduction: The aim of this study was to determine the effects of a dietary supplement containing trypsin, chymotrypsin, and serratia peptidase (Tripser Forte N30, Incir Pharma, Turkey) on postoperative healing and to determine…
- Trial name
- Trypsin (NCT07269171)
- Testing
- Pain Assessment, Number of Analgesics Needed, Edema Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Inflammation, Pain, Postoperative
Use of Corticosteroids in Third Molar Surgery
Surgical extraction of retained lower third molars is associated with the development of postoperative complications, including inflammation, trismus and postoperative pain, that lead to a decrease in patients' quality of life.
- Conditions
- Inflammation, Pain, Postoperative, Trismus
- Trial name
- NCT05752305
- Testing
- Dexamethasone 4 Mg/mL Injectable Solution, MethylPREDNISolone 40 Mg/mL Injectable Suspension
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Dental Anxiety
Aromatherapy With Lavender Essential Oil as a Complementary Treatment for the Control of Dental Anxiety
Dental anxiety is a common problem in dental care, the aim of this protocol is to evaluate the effect of lavender for the control of anxiety during a surgical dental extraction.
- Trial name
- NCT04285385
- Testing
- Lavender aromatherapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Facial Swelling, Tooth Position Anomalies
The Use of Platelet-rich-fibrin in Lower Third Molar Surgery.
The present study aims to analyze the effect of PRF (Platelet-rich-fibrin) in terms of facial swelling, trismus and pain after surgical removal of mandibular third molar (M3M) in a split-mouth randomized controlled clinical trial.
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT06165692
- Testing
- PRF
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Postoperative Pain, Postoperative Complications
Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction
The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars.
- Conditions
- Postoperative Pain, Postoperative Complications, Trismus, Periodontal Health
- Trial name
- NCT07180498
- Testing
- Chlorhexidine Gluconate 0.12% Mouthwash, Tea Tree Oil mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Harran University