Clinical trials: Thoracic Aorta
Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection
GORE® TAG® Thoracic Endoprosthesis French Mandatory Registry
This is a French Registry mandated by the French National Health Authority assessing long-term (5-years) safety of the GORE® TAG® Thoracic Endoprosthesis treating diseases of the thoracic aorta.
- Conditions
- Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection, Aortic Diseases, Aorta Thoracic; Traumatic Rupture
- Trial name
- NCT02266342
- Testing
- GORE® TAG® Thoracic Endoprostheses
- Where
- France
- Volunteers
- 154 people
- Sponsor
- W.L.Gore & Associates
Abdominal Aortic Aneurysm
Limb Remote Ischemic Preconditioning Reduces Heart and Lung Injury After Abdominal Aortic Aneurysm Repair
To investigate whether limb remote ischemic preconditioning (LRIP) has protective effects against intestinal and pulmonary injury in patients undergoing open infrarenal abdominal aortic aneurysm (AAA) repair.
- Trial name
- NCT01344239
- Testing
- Limb remote ischemic preconditioning(LRIP)
- Volunteers
- 62 people
- Sponsor
- Cai Li
Postimplantation Syndrome, Myocardial Injury
Steroid Treatment to Prevent Thoracic Endovascular Aortic Repair Postimplantation Syndrome
Postimplantation syndrome (PIS) is a common and clinically important complication following thoracic endovascular aortic repair (TEVAR).
- Conditions
- Postimplantation Syndrome, Myocardial Injury, MACE, Mortality
- Trial name
- STOP TEVAR PIS (NCT07328906)
- Testing
- Methylprednisolone (MP)
- Where
- Serbia
- Volunteers
- 174 people
- Sponsor
- University of Belgrade
Thoracic Aortic Aneurysm, Bicuspid Cardiac Valve
Indexed Aortic Area in Bicuspid Aortic Valve Aortopathy
This study aims to determine the relationship between the cross-sectional aortic area/patient height ratio (indexed aortic area) and absolute aortic diameter in proximal thoracic aortic aneurysms associated with a bicuspid valve.
- Trial name
- NCT04756778
- Testing
- Aortic surgery +/- aortic valve replacement
- Where
- United Kingdom
- Volunteers
- 69 people
- Sponsor
- St. George's Hospital, London
Aortic Aneurysm of the Proximal Arch, Aortic Aneurysms Arch
Effects of Remimazolam on Postoperative Cognitive Dysfunction and Neuroinflammatory Biomarkers in Patients Undergoing Aortic Arch Surgery
The purpose of this study is to compare remimazolam- and propofol-based anesthesia for their effects on postoperative cognitive dysfunction in patients undergoing aortic arch surgery.
- Conditions
- Aortic Aneurysm of the Proximal Arch, Aortic Aneurysms Arch, Aortic Arch Disease, Postoperative Delirium (POD)
- Trial name
- NCT07816068
- Testing
- Remimazolam Besylate, propofol
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Type B Acute Aortic Syndrome, Thoracic and Thoracoabdominal Aneurysms With Crawford Extent I, II, III, or IV
A Standard Carbon Dioxide Flushing Protocol to Reduce Air Embolization During Thoracic Endovascular Aortic Repair
FlushTEVAR is a non-profit, interventional, randomized, controlled, single-blind, national multicenter study promoted by the University of Bologna and coordinated by the Vascular Surgery Unit of IRCCS Azienda…
- Trial name
- FlushTEVAR (NCT07734584)
- Testing
- Carbon dioxide pre-implant endograft flushing followed by saline flushing, Saline endograft flushing
- Where
- 4 sites in Italy
- Volunteers
- 90 people
- Sponsor
- University of Bologna
AAOCA, ACAOS
Speed-up the Diagnosis and Evaluation of anoMalous Coronary ARTery From the Aorta
Anomalous aortic origin of the coronary arteries (AAOCA) is a rare congenital disease and one of the leading causes of sudden cardiac deaths (SCD) in young athletes but also has a lethal presentation in adult age with myocardial…
- Conditions
- AAOCA, ACAOS, Anomalous Aortic Origin of the Coronary Artery (AAOCA), Anomalous Coronary Artery Arising From the Opposite Sinus
- Trial name
- SMART (NCT06705751)
- Testing
- Autonomic response in AAOCA
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- IRCCS Policlinico S. Donato
Myocardial Protection, Minimally Invasive Surgery
Myocardial Protection in Minimally Invasive Mitral Valve Surgery
Perfusion strategies and aortic clamping techniques for right mini-thoracotomy mitral valve (MV) surgery have evolved over time and remarkable short- and long-term results have been re-ported.
- Conditions
- Myocardial Protection, Minimally Invasive Surgery, Mitral Valve Prolapse
- Trial name
- NCT04231903
- Testing
- Aortic clamp
- Volunteers
- 116 people
- Sponsor
- University of Turin, Italy
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection
Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System
This is an observational cohort study addressing the incidence of cerebral microemboli and alterations of cerebral hemodynamic physiology of the Relay®Branch thoracic stent-graft system.
- Conditions
- Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Microemboli
- Trial name
- CHaMP (NCT05155956)
- Testing
- transcranial Doppler ultrasonography (TCD)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Aortic Stenosis, Heart Failure
Quality of Life After Transcatheter Aortic Valve Implantation
This observational cohort study investigates whether hemodynamic improvements following transcatheter aortic valve implantation (TAVI) are associated with improvements in patient-reported quality of life among patients in Western…
- Conditions
- Aortic Stenosis, Heart Failure, Angina Pectoris, TAVI(Transcatheter Aortic Valve Implantation)
- Trial name
- TAVI-QoL (NCT07798713)
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Systemic Inflammatory Response Syndrome, Infections
AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis
The goal of the prospective observational study is to evaluate the immunological background of inflammatory response often seen after open thoracic aortic surgery.
- Conditions
- Systemic Inflammatory Response Syndrome, Infections, Thoracic Aortic Aneurysm, Aortic Diseases
- Trial name
- AOSIS (NCT06028789)
- Testing
- Blood sample test, Thoracic Aortic Surgery
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Hradec Kralove
Aortic Aneurysm, Thoracic, Penetrating Aortic Ulcers (PAUs)
Evaluation of Thoraflex in the Treatment of Aneurysm or Penetrating Ulcer of the Descending Thoracic Aorta
ThoraflexTM is designed for the treatment of aneurysm or penetrating ulcer of the descending thoracic aorta. Each system is advanced from a transfemoral or transiliac approach over a 0.035" guidewire and positioned under…
- Trial name
- NCT01357590
- Testing
- Thoracic Endovascular Stent Graft System (ThoraflexTM)
- Where
- 28 sites in Belgium, Canada and 5 more
- Sponsor
- Vascutek Ltd.