Clinical trials: Thoracic Epidural
Liver and Intrahepatic Bile Duct Disorder
Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery
This phase III trial studies how well thoracic epidural analgesia or four-quadrant transversus abdominus plane block works in reducing pain in patients undergoing liver surgery.
- Trial name
- NCT03214510
- Testing
- Bupivacaine, Fentanyl, Hydromorphone Hydrochloride
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- M.D. Anderson Cancer Center
General Anesthesia, Propofol Target-controlled Infusion
Effects of Epidural Local Anesthetics on Propofol Induction
The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.
- Conditions
- General Anesthesia, Propofol Target-controlled Infusion, Thoracic Epidural Anesthesia
- Trial name
- NCT02000973
- Testing
- Lidocaine, Bupivacaine, Ropivacaine
- Volunteers
- 80 people
- Sponsor
- First Hospital of China Medical University
Epidural Block, Oesophageal Cancer
The Hemodynamic Effect Between Two Types of Anesthesia in Esophageal Surgery
Continuous Paravertebral block (PVB) was reported to provide less episodes of hypotension than continuous thoracic epidural block (TEB).
- Conditions
- Epidural Block, Oesophageal Cancer, Oesophagectomy
- Trial name
- HEMOBLOC (NCT03185403)
- Testing
- paravertebral block, thoracic epidural block, ropivacaine
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Pain, Chronic
Comparison of Pain Relief Between High Thoracic Erector Spinae Plane Block and Cervical Epidural Injection
The primary endpoint of this study was to identify whether there is a pain improving effect of high thoracic eretor spinae plane block (ESPB) when compared with cervical epidural injection
- Trial name
- NCT05487326
- Testing
- Erector spinae plane block, cervical epidural injection
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Keimyung University Dongsan Medical Center
Postoperative Pain
The Postoperative Analgesic Effect of Combination With Dexmedetomidine in Fentanyl-based Intravenous Patient Controlled Analgesia Compared With Conventional Thoracic Epidural and Intravenous Patient Controlled Analgesia After Radical Open Gastrectomy
The aim of this study to test hypothesis that addition of dexmedetomidine to fentanyl based intravenous patient controlled analgesia (PCA) improves postoperative pain compared with conventional thoracic epidural and intravenous…
- Trial name
- NCT02325882
- Testing
- Dexmedetomidine, Fentanyl 1, Fentanyl 2
- Where
- South Korea
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Thoracic Epidural Anesthesia
CompuFlo Thoracic Epidural Study
Traditionally, loss-of-resistance (LOR) to air or saline with a special ground-glass syringe is the technique used to identify epidural space, but failure rates up to 30% have been reported using this technique for thoracic…
- Trial name
- NCT03826186
- Testing
- Traditional (loss-of-resistance technique) thoracic epidural placement, CompuFlo thoracic epidural placement
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- YATISH SIDDAPURA RANGANATH
3 or More Rib Fractures
Optimal Method of Pain Management in Patients With Multiple Rib Fractures
Rib fractures are a common injury of trauma patients and can cause significant pain which, if inadequately treated, can lead to impaired breathing, lung collapse, and respiratory failure.
- Trial name
- NCT01401712
- Testing
- ON-Q® Pain Relief System, Thoracic epidural catheter
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Massachusetts General Hospital
Pain, Postoperative, Surgery, Thoracic
Multimodal Analgesia in Children and Adolescents After the Ravitch Procedure and Thoracotomy
The study was performed in patients aged 6-18 years after the Ravitch procedure and thoracotomy. The primary aim of the study was to evaluate the efficacy and safety of pain control provided by the multimodal approach that…
- Trial name
- NCT03444636
- Testing
- Ropivacaine/Fentanyl, Bupivacaine/Fentanyl
- Where
- Poland
- Volunteers
- 94 people
- Sponsor
- National Institute for Tuberculosis and Lung Diseases, Poland
Lung Cancer, Acute Pain
US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy
Thoracic surgeries is known to be one of the most painful surgeries . Multiple analgesic techniques have been used for post operative analgesia including Thoracic epidural , Patient Controlled Analgesia and systemic opioids.
- Conditions
- Lung Cancer, Acute Pain, Chronic Pain
- Trial name
- NCT05672394
- Testing
- Continuous Serratus anterior plane block, Thoracic Epidural, Bupivacaine
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- National Cancer Institute, Egypt
Pectus Excavatum, Pain, Postoperative
Pectus ESC Outcomes and Comparative Effectiveness Study
Investigators hypothesize that Erector spinae catheter pain management protocol would allow patients to have earlier and more effective rehabilitation with decreased length of hospital stay.
- Trial name
- PectusESC (NCT05063695)
- Testing
- Multimodal Erector spinae catheter protocol
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Lung Diseases, Pain, Acute
TEA, ESB and Paravertebral Block During Single-lung Ventilation for Lung Resection
Thoracotomy operations are known to be painful surgical procedures, so providing effective intraoperative and postoperative analgesia is so important for all anaesthesiologists.
- Trial name
- NCT05211791
- Testing
- erector spinae block, paravertebral block anesthesia, Thoracic epidural anesthesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- South Egypt Cancer Institute
Chest Trauma
Erector Spinae Plane Block Versus Thoracic Epidural Block for Chest Trauma
Rib fractures are very common as a consequence of blunt chest trauma which is associated with severe pain, morbidity and mortality.
- Trial name
- NCT03797079
- Testing
- ESP block, TEA, Catheter insertion
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sameh Fathy
Pain, Postoperative
The Effect of Gabapentin on Thoracic Epidural Analgesia Following Thoracotomy
The purpose of this trial is to investigate the effect of gabapentin on thoracic epidural analgesia following thoracotomy, including assessment of both analgesia, pain intensity, pain quality and whether or not gabapentin…
- Trial name
- GABATEA (NCT01116583)
- Testing
- Gabapentin
- Where
- Denmark
- Volunteers
- 104 people
- Sponsor
- University of Aarhus
Postoperative Pain Management
Postoperative Analgesia in Thoracic Surgery
Analgesic management in thoracic surgery presents a particular challenge for the anesthesiologist, given the intensity of postoperative pain associated with thoracotomy, a surgical procedure that can impact respiratory function…
- Trial name
- ARP-TS (NCT07694141)
- Testing
- Postoperative pain through Visual analogue scale, Postoperative complications
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Ultrasound, Multilevel Erector Spinae Plane Block
Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients
The aim of this study is to compare the analgesic efficacy of multilevel erector spinae plane block (ESPB) vs thoracic epidural in modified radical mastectomy (MRM) regarding duration of analgesia, postoperative opioid…
- Conditions
- Ultrasound, Multilevel Erector Spinae Plane Block, Thoracic Epidural Analgesia, Post Mastectomy
- Trial name
- NCT06884852
- Testing
- Erector spinae plane block (ESPB), Thoracic epidural block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Cancer Institute, Egypt
Ultrasound Guided Serratus Plane Block, Thoracic Epidural
Ultrasound Guided Serratus Plane Block Versus Thoracic Epidural for Post Thoracotomy Pain
This study aims at comparing the effect of serratus plane block versus thoracic epidural in patients undergoing thoracotomy for lung cancer surgery regarding pain control and possible side effects.
- Conditions
- Ultrasound Guided Serratus Plane Block, Thoracic Epidural, Post Thoracotomy Pain
- Trial name
- NCT03933592
- Testing
- Serratus anterior block, thoracic epidural
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Epidural Placement
Epidural Wave Form Analysis vs Fluoroscopic Guidance for Thoracic Epidural Placement
The primary objective of this study is to compare the effectiveness of epidural waveform analysis (EWA) with fluoroscopic guidance for confirmation of successful epidural placement.
- Trial name
- NCT07217457
- Testing
- Epidural Waveform Analysis
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pectus Excavatum, Pain, Postoperative
Identification of Best Postoperative Analgesia Method Following a Minimally Invasive Repair of Pectus Excavatum
Pectus excavatum is the most common chest wall deformity in children, accounting for 90% of all congenital chest wall deformities. It occurs in one to eight per 1000 live births.
- Trial name
- (MIRPE) (NCT04211935)
- Testing
- Use of PCA, Use of ESB for postoperative pain control after MIRPE, Use of INC for postoperative pain control after MIRPE
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Post Thoracic Surgery
Intrapleural Bupivacaine for Ipsilateral Shoulder Pain After Thoracotomy
While thoracic epidural could control incisional pain after thoracotomy, an excruciating ipsilateral shoulder pain happens post thoracotomy and could affect up to 85% of thoracotomy patients.
- Trial name
- NCT03862404
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Subcostal, Lateral
Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery
This study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal…
- Conditions
- Subcostal, Lateral, Transversus Abdominis Plane Block, Postoperative Analgesia
- Trial name
- NCT07273136
- Testing
- Subcostal and lateral transversus abdominis plane block, Thoracic epidural anesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University