Clinical trials: Thoracic Trauma
Rib Fractures
Cryo Rib Fracture Study
The purpose of this study is to determine if patients with rib fractures who undergo cryoablation of the intercostal nerves have improved pain control 7 days from procedure when compared to those who have a ESP catheter.
- Trial name
- NCT06347874
- Testing
- Cryoablation, ESP Catheter
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Minnesota
Rib Fracture, Cartilage Damage
Point of Care Ultrasound (POCUS) for Diagnosis and Treatment of Fractures in the Costal Cartilage
The goal of this observational study is to learn if combining ultrasound and CT scans can better diagnose cartilage fractures in the ribs, and to understand how finding these injuries affects treatment decisions for patients with…
- Trial name
- NCT07338617
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Thoracic Aorta
Aortic Elongation and Dissection
Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.
- Trial name
- NCT02722889
- Where
- Netherlands
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Acute Respiratory Distress Syndrome (ARDS), Extracorporeal Membrane Oxygenation
Personalized Ventilator Settings for Patients on ECMO
While mechanical ventilation can be used to sustain life in those with lung injury, it, can further worsen lung injury or prevent lung healing resulting in high morbidity and mortality as seen in Acute Respiratory Distress…
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Extracorporeal Membrane Oxygenation, Respiratory Failure Patients Treated With ECMO, Respiratory Failure, ICU
- Trial name
- PEEPECMO (NCT07673250)
- Testing
- Personalized Positive End-Expiratory Pressure (PEEP)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, San Diego
Non Small Cell Lung Cancer, Small Cell Lung Cancer
Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic Malignancies
Hypothesis 1- Using IMRT, the radiation therapy (RT) dose can be safely escalated from 58 Gy to 74 Gy given as 6 fractions/week with concurrent chemotherapy.
- Conditions
- Non Small Cell Lung Cancer, Small Cell Lung Cancer, Thymoma, Thymus Neoplasms
- Trial name
- ESIMRT (NCT00921739)
- Testing
- Esophageal sparing IMRT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Cardiovascular Disease, Acute Renal Failure
The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure
The purpose of this trial is to study the use of nesiritide in thoracic aneurysm repair to prevent acute renal failure. The study hypothesis: Nesiritide, given prophylactically prior to surgery may prevent acute renal failure…
- Conditions
- Cardiovascular Disease, Acute Renal Failure, Death
- Trial name
- NCT00110201
- Testing
- Nesiritide
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Ejaz, Abulate A, MD
Radiotherapy Side Effect, Non-small Cell Lung Cancer
Alectinib Followed by Concomitant Consolidation Radiation Therapy in Advanced NSCLC With ALK-rearrangement (A-SAB)
The goal of this clinical trial is to learn evaluate the safety and efficacy of the addition of radiation therapy to all tumour lesions, to first line medical treatment with alectinib in non-small cell lung cancer harbouring…
- Conditions
- Radiotherapy Side Effect, Non-small Cell Lung Cancer, ALK Gene Mutation
- Trial name
- A-SAB (NCT05724004)
- Testing
- SBRT/SRS/radiation therapy
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Karolinska University Hospital
Hypertrophic Scars, Post-burn Scars
Nano-Fat Grafting for Post-Burn Scars on the Chest, Shoulders, and Back
This study aims to evaluate the effectiveness of nano-fat grafting in treating hypertrophic scars caused by burns on the chest, shoulders, and back.
- Conditions
- Hypertrophic Scars, Post-burn Scars, Burns
- Trial name
- NCT07557472
- Testing
- Autologous Nano-Fat Grafting
- Volunteers
- 55 people
- Sponsor
- Assiut University
Bronchopulmonary Dysplasia
Ultrasound Assessment of Diaphragmatic Function in Infants With BPD
Preterm infants have high and prolonged exposure to positive pressure ventilation, which contributes to acute lung injury and the development of bronchopulmonary dysplasia (BPD).
- Trial name
- NCT04941963
- Testing
- Chest ultrasound
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Mount Sinai Hospital, Canada
Pneumothorax and Air Leak, Pneumothorax
Urine Bag Usage Versus Chest Drain Clamping After Lung Resection Surgeries
Investigators will compare two different approaches of postoperative drainage after the standard water-seal drain has been used efficiently; one is by using urine bag and check it get blown by the leaked air, two is by using…
- Conditions
- Pneumothorax and Air Leak, Pneumothorax, Pleura Injury, Pleural Effusion
- Trial name
- NCT05230420
- Testing
- Clamping, Urine bag
- Where
- 4 sites in Egypt, Italy and 1 more
- Volunteers
- 160 people
- Sponsor
- Al-Quds University
Lung Cancer, Interstitial Lung Disease
Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease
In this double-blind phase II randomized controlled trial, patients with lung cancer or ≤2 oligometastatic pulmonary lesions and a concomitant diagnosis of ILD who are planned for radical Radiation Therapy (RT) will be randomized…
- Trial name
- RESPIRE-ILD (NCT05986318)
- Testing
- N-Acetyl cysteine, Dexamethasone Oral, Radiation Therapy
- Where
- 4 sites in Canada
- Volunteers
- 98 people
- Sponsor
- David Palma
Thoracic Surgery, Cardiopulmonary Bypass
Cerebral Autoregulation Monitoring During Cardiac Surgery
Neurological complications from cardiac surgery are an important source of operative mortality, prolonged hospitalization, health care expenditure, and impaired quality of life.
- Trial name
- NCT00981474
- Testing
- blood pressure maintenance based on cerebral blood flow autoregulation measurement, Control group
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Northwestern University
ARDS (Acute Respiratory Distress Syndrome), AI (Artificial Intelligence)
Exploration of Diagnosis and Treatment Strategies and Prognostic Prediction Models for Acute Respiratory Distress Syndrome Based on Radiographic Evaluations Assessed by Artificial Intelligence
By using multi-center chest CT data, an intelligent assessment model for the severity of ARDS was constructed. Based on CT quantitative features and clinical characteristics, a prediction model for short-term critical events…
- Trial name
- NCT07328997
- Testing
- CT scan
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Zhongshan Hospital
Rib Fracture, Rib Fracture Multiple
Zimmer Biomet-RibFix Titan
Prospective, single-center, non-randomized, single-cohort, post-market clinical follow-up study to confirm the safety, performance, and clinical benefits for the use of the RibFix Titan™ system implants and instrumentation) in…
- Trial name
- NCT07485829
- Testing
- The RibFix Titan™ device should be used within this arm of the study.
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Zimmer Biomet
Fracture; Rib, Multiple
Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Patients With Multiple Fracture Ribs
To assess the analgesic and respiratory effect of continuous Erector Spinae Plane block versus Thoracic Epidural in patients with multiple fracture ribs.
- Trial name
- NCT03853330
- Testing
- Ultrasound, Bupivacaine HCl Inj 0.25%, Bupivacaine Hydrochloride, 0.125%-0.9% Injectable Solution
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Assiut University
Anxiety, Depression
Meditation-Based Breathing Training in Improving Target Motion Management and Reducing Distress in Patients With Abdominal or Lung Cancer Undergoing Radiation Therapy
This randomized pilot clinical trial studies the effects of meditation-based breathing training on patients' control of their breathing patterns and breathing-related movement, as well as on their psychological distress and…
- Conditions
- Anxiety, Depression, Digestive System Neoplasm, Lung Neoplasm
- Trial name
- NCT01939210
- Testing
- Educational Intervention, Meditation Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Albert Einstein College of Medicine
Brain Injury, Intracranial Hypertension
Automated Chest Physiotherapy to Improve Outcomes in Neuro
Following current standard-of-care, subjects data (brain pressure) will be recorded for 1 hour and include 10-minutes of data during which the subject recieves chest physiotherapy (CPT).
- Trial name
- ACTION-ICP (NCT00571623)
- Testing
- Chest Physiotherapy
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Post Operative Pain
Analgesia After Video-Assisted Thoracic Surgery
Although less invasive, postoperative analgesia remains challenging in patients undergoing uniportal video-assisted thoracic surgery (VATS).
- Trial name
- NCT05094323
- Testing
- Ultrasound-guided deep serratus anterior plane block with isobaric bupivacaine, Local wound infiltration with isobaric bupivacaine, Ultrasound-guided thoracic paravertebral block with isobaric bupivacaine
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Assiut University
Acute Brain Injury
Chest Physiotherapy Effects on Intracranial Pressure
The investigators will study the effects of a chest physiotherapy technique (rapid thoracic compression) on the intracranial pressure of individuals with acute cerebral injury and with need of intubated mechanical ventilation
- Trial name
- NCT03609866
- Testing
- rapid thoracic compression technique, inferior limb passive mobilization
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Santiago de Compostela
Unstable Cervical Injury
Determining Optimal Halo Pin Management Practises to Decrease Pin Complications
The purpose of this study is to evaluate the effects of regular pin re-tensioning on pain, pin loosening and pin replacement.
- Trial name
- NCT00480727
- Testing
- Halo pin re-tensioning
- Where
- Australia
- Volunteers
- 44 people
- Sponsor
- Bayside Health