Clinical trials: Thoracoscopic Surgeries
Lung Cancer, Complication of Surgical Procedure
Comparison of LigaSure to Conventional Electrocoagulation in Video-assisted Thoracoscopic Surgery Lobectomy
Surgical treatment of lung cancer consists of two elements: anatomical lung resection (segmentectomy, lobectomy or pneumonectomy) followed by mediastinal lymph node dissection (MLND).
- Trial name
- NCT03125798
- Testing
- LigaSure™, Monopolar electrocautery
- Where
- Poland
- Volunteers
- 216 people
- Sponsor
- Wielkopolskie Centrum Pulmonologii i Torakochirurgii
Video-assisted Thoracoscopic Surgery (VATS), One-lung Ventilation
IPg2 Study: Left-sided Lung Isolation
Lung isolation is primordial in thoracic surgery. To achieve it, two techniques are used: the double lumen tube (DLT) and the bronchial blocker (BB).
- Trial name
- IPg2 (NCT02137291)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Edge of Laminar Block, Erector Spinae Plane Block
Edge of Laminar Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Video-Assisted Thoracoscopic Surgery
This study aims to compare the ultrasound-guided edge of laminar block (ELB) and erector spinae plane block (ESPB) for postoperative analgesia in patients undergoing video-assisted thoracic surgery (VATS).
- Conditions
- Edge of Laminar Block, Erector Spinae Plane Block, Postoperative Analgesia, Video-Assisted Thoracoscopic Surgery
- Trial name
- NCT07201285
- Testing
- Edge of laminar block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
One-Lung Ventilation, Thoracic Surgery Video Assisted
The Effects of Different Types of Non-ventilated Lung Management on DO2 During OLV in the Supine Position
The aim of this study is the comparison of oxygen delivery during OLV+capnothorax and OLV+capnothorax and CPAP.
- Conditions
- One-Lung Ventilation, Thoracic Surgery Video Assisted, Supine Position
- Trial name
- OLVinFACHIR (NCT02959515)
- Testing
- Capnothorax, Capnothorax and CPAP
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Centro Cardiologico Monzino
Chronic Pain, Acute Pain
Intra-operative Lidocaine Infusion in Preventing CPSP Post VATs
The aim of this study is to evaluate the impact of intravenous lidocaine on acute and chronic post surgical pain on patients undergoing video assisted thoracoscopic surgery(VATS).
- Conditions
- Chronic Pain, Acute Pain, Neuralgia
- Trial name
- NCT02862769
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Acute Postoperative Pain, Chronic Postoperative Pain
Comparison of the Efficacy and Safety of Intravenous Buprenorphine Administered Via PCA System Versus Oxycodone in the Management of Postoperative Pain After Video-Assisted Thoracoscopic Surgery
The goal of this clinical trial is to learn whether intravenous buprenorphine administered via a patient-controlled analgesia (PCA) system provides effective and safer postoperative pain control than intravenous oxycodone PCA in…
- Conditions
- Acute Postoperative Pain, Chronic Postoperative Pain, Toracosurgery, Video-assisted Thoracis Surgery (VATS)
- Trial name
- NCT07434427
- Testing
- Group B (Buprenorphine), Group O (Oxycodone)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Silesia
Video Assisted Thoracoscopic Surgery, Postoperative Analgesia
Serratus Posterior Superior Intekcostal Plane Block vs Serratus Anterior Plane Block for Postoperative Analgesia in VATS: A Randomized Trial"
Thoracotomy is known as one of the most painful surgical procedures, with up to 65% of patients developing chronic post-thoracotomy pain syndrome (PTPS), and approximately 10% experiencing pain that significantly impacts quality…
- Trial name
- NCT07020624
- Testing
- SAPB, SPSIPB
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Samsun University
Non-small Cell Lung Cancer
Assisted-VATS Sleeve Lobectomy for Non-small Cell Lung Cancer
The purpose of this study is to examine the feasibility of assisted-VATS (video-assisted thoracoscopic surgery) sleeve lobectomy for non-small cell lung cancer for non-small cell lung cancer.
- Trial name
- VATS (NCT00997724)
- Testing
- a-VATS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Local Analgesia Via Nerve Block
A Study of Bupivacaine Liposome Injection in the Treatment of Pain After Thoracoscopic Surgery
The objective of this study is to evaluate the efficacy, safety, and tolerability of bupivacaine liposomes for paravertebral nerve block in the treatment of thoracoscopic postoperative pain, and to evaluate the relevant human…
- Trial name
- NCT06529432
- Testing
- Bupivacaine Liposome Injection, Bupivacaine Hydrochloride Injection
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Women, Asian
Effect of Small Double-lumen Tube on the Intubation Time of Thoracoscopic Pulmonectomy in Asian Women
The purpose of this experiment is to verify whether selecting a double-lumen tube one size smaller based on the traditional personalized method can shorten the intubation time without increasing ventilation complications when…
- Conditions
- Women, Asian, Thoracic Surgery With One-lung Ventilation
- Trial name
- NCT07097584
- Testing
- Selecting the size of a Left Double-lumen endobronchialtube one size smaller than the traditional method, Selecting the size of a Left Double-lumen endobronchialtube according to traditional methods
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Zhejiang Cancer Hospital
Pleural Effusion
Comparison of Thoracoscopic Talc Pleurodesis by Thoracic Epidural or General Anesthesia
Video-assisted thoracoscopic surgery (VATS) talc pleurodesis is often carried out in patients with malignant recurrent pleural effusion to relieve symptoms and prevent recurrence.
- Trial name
- NCT01469728
- Testing
- Non-awake VATS talc pleurodesis, Awake VATS talc pleurodesis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Lung Cancer (Suspected or Confirmed), Thoracoscopic Lobectomy
Right Ventricular Afterload Indices in Lung Surgery
Lung cancer is a leading cause of cancer death in Scotland and the UK. Surgery, typically using a keyhole approach, provides the best chance of cure.
- Conditions
- Lung Cancer (Suspected or Confirmed), Thoracoscopic Lobectomy, One Lung Ventillation (OLV)
- Trial name
- RAILS (NCT07812207)
- Testing
- Contrast cardiac magnetic resonance imaging, Right heart catheterisation, Perioperative plasma sampling
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Breast Carcinoma, Prostate Cancer Surgery
High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins
These are patients in whom a benign or malignant tumor was recorded requiring surgery. During that surgery, the surgeon will cut away the tumor as part of the treatment of the disease.
- Conditions
- Breast Carcinoma, Prostate Cancer Surgery, Thyroid Cancer, Parathyroid Adenomas
- Trial name
- NCT06835426
- Testing
- Single intravenous injection of the radiotracer, Imaging resected specimen using the high-resolution PET-CT specimen imager
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Postoperative Pain, Thoracic Surgery, Video Assisted
Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
This prospective randomized controlled trial was conducted to compare the effectiveness of two ultrasound-guided regional anesthesia techniques, erector spinae plane block (ESPB) and serratus posterior superior intercostal plane…
- Trial name
- NCT07426692
- Testing
- Erector Spinae Plane Block (ESPB) group, Serratus posterior superior intercostal plane block, Morfin
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Marmara University
Non-small Cell Lung Cancer
Suction on Post-Operative Chest Tubes
The level of suction on post-operative chest tubes after video-assisted thoracoscopic surgery (VATS) lobectomy for lung cancer has previously shown to affect duration of drainage.
- Trial name
- SPOCT (NCT02911259)
- Testing
- Suction is set to -2 cmH2O, Suction is set to -10 cmH2O
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery
Video-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery
Right-sided double-lumen tubes are used for lung isolation during thoracoscopic surgery but can be difficult to position because of right bronchial anatomy.
- Conditions
- Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery, One-lung Ventilation, Lung Cancer
- Trial name
- NCT07849400
- Testing
- Continuous video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube
- Where
- 3 sites in China
- Volunteers
- 566 people
- Sponsor
- Diansan Su
Lung Cancer, Thoracic Surgery, Video-Assisted
3D Lung Reconstructions Using Open-source Software for Lung Cancer Surgery
Preoperative three-dimensional (3D) lung reconstructions can reduce intraoperative blood loss, conversion rate, and operation duration.
- Conditions
- Lung Cancer, Thoracic Surgery, Video-Assisted, Lobectomy, Segmentectomy
- Trial name
- 3D-LUNG (NCT06132607)
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Erik de Loos
Oxycodone
Oxycodone in Combination With Parathoracic Nerve Block is Used for Postoperative Analgesia in Lung Cancer
In this study, the effect of oxycodone combined with ultrasound-guided paravertebral nerve block on the postoperative analgesic effect of thoracoscopic lung cancer was investigated, and the effect and reasonable dose of oxycodone…
- Trial name
- NCT05742256
- Testing
- Oxycodone 1mg/kg, Oxycodone 1.5mg/kg, Sufentanil
- Volunteers
- 159 people
- Sponsor
- Qianfoshan Hospital
Postoperative Pain
The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery
This study aimed to assess the effectiveness of Coenzyme Q10 in preventing both acute and chronic pain following thoracoscopic surgery, with a focus on its potential benefits in reducing the incidence and severity of pain.
- Trial name
- NCT06743802
- Testing
- Coenzyme Q10
- Where
- China
- Volunteers
- 264 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Lung Nodules
Pre-Emptive Parecoxib Sodium for Pain Control During CT-Guided Lung Nodule Localization
Before undergoing minimally invasive lung surgery, patients with small lung nodules often need a procedure called "CT-guided hook wire localization." This involves using a CT scanner to help doctors place a tiny wire in the lung…
- Trial name
- PEARL (NCT07675473)
- Testing
- PARECOXIB SODIUM, 0.9 % Normal Saline
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Long Jiang