Clinical trials: Thoracoscopy
Pleural Infection, Empyema
Fibrinolysis Compared to Thoracoscopy for Pleural Infection
The purpose of this prospective randomized clinical trial is to compare two currently accepted standard-of-care treatment strategies: Medical thoracoscopy as compared to instillation of intrapleural tissue Plasminogen Activator…
- Conditions
- Pleural Infection, Empyema, Pleural Diseases, Parapneumonic Effusion
- Trial name
- NCT03468933
- Testing
- tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase), Medical Thoracoscopy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Tulane University
Chagas Cardiomyopathy, Ventricular Arrythmia
Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease
Ventricular tachycardia (VT) is the main cause of sudden death in patients with structural heart diseases. The use of ICD (implantable cardio-defibrillator) could prevent sudden death, however, the occurrence of repetitive shock…
- Trial name
- NCT04239144
- Testing
- Bilateral sympathectomy, Catheter ablation
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
Non Small Cell Lung Cancer
Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer
This is a prospective randomized clinical trial with the study cohort comprised of all male and female patients over the age of 21 presenting to the study site for evaluation of lung cancer.
- Trial name
- NCT00970645
- Testing
- Mediastinoscopy/thoracoscopy, EBUS/EUS
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Lung Cancer
Thoracoscopic Lobectomy Using Nonintubated Anesthesia Versus Intubated General Anesthesia for Lung Cancer Patients
The purpose of this study is to study the safety and results of thoracoscopic lobectomy using non-intubated thoracic epidural anesthesia versus intubated general anesthesia for lung cancer patients.
- Trial name
- NCT01533233
- Testing
- thoracoscopic lobectomy and mediastinal lymph node dissection
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Pleural Effusion
Medical Thoracoscopy With Flexible Bronchoscopy Versus Semi-Rigid Pleuroscope in Pleural Effusion (FLEXPLEUR)
Pleural effusion is a common problem in hospital patients. It may arise from a wide range of diseases. There is a multitude of recognised causes of pleural effusion, and in addition, other pleural conditions such as pleural…
- Trial name
- FLEXPLEUR (NCT06162429)
- Testing
- Flexible Bronchoscopy, Semi-Rigid Pleuroscopy
- Where
- Malaysia
- Volunteers
- 188 people
- Sponsor
- National University of Malaysia
Pleural Effusion
Mini Thoracoscopy vs Semirigid Thoracoscopy in Exudative Pleural Effusions
Undiagnosed pleural effusion is a diagnostic dilemma especially in exudative pleural effusions (EPE). 20-40 % are unable to be attributed to a specific diagnosis, even after thoracentesis and closed pleural biopsy.
- Trial name
- MIST (NCT02851927)
- Testing
- Mini Thoracoscopy, SemiRigid Thoracoscopy
- Where
- India
- Volunteers
- 73 people
- Sponsor
- All India Institute of Medical Sciences
Lung Neoplasm, Physiology
Significance of Early Mobilization After VATS-L
The main endpoint is physiological rehabilitation after VATS-L under early mobilization. The secondary endpoints are exploring the effect of early mobilization on postoperative physiology.
- Conditions
- Lung Neoplasm, Physiology, Exercise, Lung Function
- Trial name
- NCT04508270
- Testing
- Early mobilization
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pleural Effusion, Exudative Pleural Effusion
Forceps Versus Cryobiopsy in Undiagnosed Exudative Pleural Effusion Using Rigid Thoracoscopy
This study compared two ways of taking tissue samples from the lining of the lung (pleura) during rigid thoracoscopy in adults with pleural effusion of unknown cause: conventional forceps biopsy and cryobiopsy (freezing the…
- Conditions
- Pleural Effusion, Exudative Pleural Effusion, Mesothelioma
- Trial name
- NCT07869056
- Testing
- Pleural Cryobiopsy, Pleural Forceps Biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Ahmed Zakaria Elsaeed
Video-assisted Thoracoscopic Surgery, One-Lung Ventilation
Compared Unidirectional Valve Apparatus and Occluding the Non-ventilated Endobronchial Lumen for Lung Collapse.
With the rapid advancement of thoracoscopic surgery in recent years, surgeons have set higher standards for the quality of non-ventilated lung collapse.
- Trial name
- NCT06210256
- Testing
- unidirectional valve apparatus, occluding the non-ventilated endobronchial lumen
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Sichuan University
Pain, Postoperative, Thoracic Surgery, Video-Assisted
Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy
Postoperative pain remains relatively high within 48h for Chinese patients who receive video-assisted thoracoscopic surgery. Multimodal analgesia combines several agents and/or techniques to function on diverse nociceptive…
- Trial name
- NCT03648008
- Testing
- Hydromorphone, Morphine
- Where
- China
- Volunteers
- 171 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pleural Effusion, Cancer
Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions
This is a randomized control trial of patients with suspected malignant pleural effusions to compare whether patients who have a thoracentesis or pleuroscopy (pleural biopsy) obtain an adequate biopsy, achieve a diagnosis, and…
- Trial name
- PERFECT-MPE (NCT06892691)
- Testing
- Pleuroscopy first, Thoracentesis first
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Thoracoscopy, Anesthesia; Functional
Anesthetic Component Research on VATS and NIVATS
The non-intubated video-assisted thoracic surgery (NIVATS) can avoid intubation-related complications and for a smoother postoperative recovery.
- Conditions
- Thoracoscopy, Anesthesia; Functional, Tracheal Intubation
- Trial name
- NCT03874403
- Testing
- DSA
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Pain
Pain Management in Response to Exparel vs. Standard Bupivicaine
This study is looking to evaluate the efficacy of liposomal bupivicaine (Exparel) on decreasing the amount of consumed pain medications.
- Trial name
- VATS Exparel (NCT02499159)
- Testing
- Liposomal Bupivicaine, 0.25% standard bupivicaine
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Inova Health Care Services
Postoperative Pain
The Effect of Phrenic Nerve Blockade on Acute and Chronic Shoulder Pain in Patients for Lobectomy and Pneumonectomy
The purpose of this study was to test whether peroperative infiltration of the phrenic nerve during lung surgery would protect patients against postoperative shoulder pain.
- Trial name
- TOPBLOC (NCT02173418)
- Testing
- Phrenic nerve block with Ropivacaine, Phrenic nerve block with saline
- Where
- Denmark
- Volunteers
- 76 people
- Sponsor
- Odense University Hospital
Pulmonary Procedures
Registry for Patients Undergoing Pulmonary Procedures
The purpose of this research study is to examine the safety, tolerability, and effectiveness of currently available pulmonary procedures when used to diagnose or treat different diseases.
- Trial name
- NCT01397292
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Virginia Commonwealth University
Giant Thoracic Herniation, Myelopathy
Management of Giant Thoracic Disc Hernias by Thoracoscopy: Experience of 52 Cases
Introduction: Giant thoracic disc herniation is a rare condition for which surgical treatment is indicated when there are signs of spinal cord injury.
- Trial name
- GHTT (NCT03295617)
- Testing
- Thoracoscopy
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Hopital Foch
Thoracic Surgery, Video-Assisted
Erector Spinae Plane (ESP) Block vs Intravenous Lignocaine Infusion in (VATS)
The goal of this clinical trial is to compare analgesic efficacy of erector spinae plane (ESP) block vs intravenous lignocaine infusion in video- assisted thoracoscopy (VATS.
- Trial name
- NCT06289790
- Testing
- Erector Spinae Plane (ESP) block, Lignocaine, Bupivacaine
- Where
- Poland
- Volunteers
- 61 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Pleural Effusion, Pleurisy
Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy
This is a prospective study to assess the efficacy and safety of a single dose of cefazolin 2g IV for the prophylaxis of surgical site and pleural space infections in patients undergoing medical thoracoscopy.
- Conditions
- Pleural Effusion, Pleurisy, Empyema
- Trial name
- APT (NCT02446782)
- Testing
- Cefazolin, saline
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pleural Infection, Pleural Infections
Role of Medical Thoracoscopy in Pleural Infection (PROMPT Trial)
The PROMPT study is testing whether an early keyhole procedure called Medical Thoracoscopy, which lets doctors look inside the chest and remove infected fluid, works better than current standard treatment (medicines to break up…
- Conditions
- Pleural Infection, Pleural Infections, Pleural Infections and Inflammations
- Trial name
- PROMPT (NCT07550530)
- Testing
- medical thoracoscopy, Standard of Care
- Volunteers
- 170 people
- Sponsor
- Università Politecnica delle Marche
PLEURA DISEASE
Ultrasound Guided Erectror Spinae Block Versus Intracavitary During Medical Thoracoscopy
The primary aim: is to compare the effect of US guided ESP block at two levels versus intracavitary blockade in medical thoracoscopy on total peri-procedural (intraoperative and post-operative 12 hours) nalbuphine consumption…
- Trial name
- ESPB (NCT07572019)
- Testing
- ultrasound-guided erector spinae plane block in medical pleuroscopy, Intracavitary anaesthesia ICA
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University