Clinical trials: Thoracoscopy
Complicated Parapneumonic Effusion, Pleural Empyema
Early Medical Thoracoscopy Versus Simple Chest Tube Drainage in Complicated Parapneumonic Effusion and Pleural Empyema
Multicenter, randomized controlled study to compare early mini-invasive thoracoscopy to simple chest tube drainage in complicated parapneumonic effusions or pleural empyema. 100 patients will be recruited.
- Trial name
- NCT00234208
- Testing
- Medical thoracoscopy, Simple chest tube drainage
- Where
- 5 sites in Greece, Italy and 1 more
- Volunteers
- 2 people
- Sponsor
- University Hospital, Basel, Switzerland
Lung Neoplasms
Effects of Nonintubated Versus Intubated General Anesthesia on Recovery After Thoracoscopic Lung Resection
Lung cancer is the leading cause of cancer death in Taiwan and worldwide. With the advancement of thoracoscopic technique, thoracoscopic surgery has emerged as a reasonable option for the management of early-stage non-small cell…
- Trial name
- NCT02393664
- Testing
- propofol, bupivacaine, sevoflurane, rocuronium
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Recurrent Malignant Pleural Effusion.
Talc Pleurodesis in Patients With Recurrent Malignant Pleural Effusion
The purpose of this study is to analyze and compare radiological lung expansion after talc pleurodesis performed either by videothoracoscopy or chest tube and correlate it with clinical outcome.
- Trial name
- NCT00789087
- Testing
- Videothoracoscopic talc poudrage (VT)., Talc slurry through a chest tube (DT).
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Post Operative Pain, Opioid Use
Ultrasound-guided Erector Spinae Plane Block Using Catheter for Video-assisted Thoracoscopy
Different modalities ranging from patient controlled analgesia (PCA) to different regional blocks have been used to control postoperative pain after thoracic surgeries.
- Trial name
- NCT05337956
- Testing
- Erector spinae plane block catheter
- Where
- Saudi Arabia
- Volunteers
- 34 people
- Sponsor
- Security Forces Hospital
Lung Neoplasms
Pre-operative Localization of Ground Glass Solitary Pulmonary Nodules
Objectives: The main drawback of the hook-wire technique for locating ground glass nodules before video assisted thoracoscopic surgery (VATS) resection is the risk of the hook dislodging during single lung ventilation as the lung…
- Trial name
- SLIDINGWIRE (NCT06195657)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Diagnosis of Pleural Diseases
Image-guided Pleural Biopsy or Medical Thoracosocopy in Diagnosis of Pleural Disease
Pleural diseases can occur due to numerous pathological conditions. The increasing prevalence of etiologic causes and aging population worldwide will make pleural diseases a growing problem in the coming years.
- Trial name
- NCT05428891
- Testing
- Abrams' needle pleural biopsy (IG-ANPB) versus medical thoracoscopy in the diagnosis of pleural diseases.
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Malignant Neoplasm, Malignant Respiratory Tract Neoplasm
Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy
This trial studies how well rapid on site evaluation of pleural touch preparations works in diagnosing cancerous fluid in between the linings of the lungs (malignant pleural effusion) in patients undergoing a pleuroscopy.
- Conditions
- Malignant Neoplasm, Malignant Respiratory Tract Neoplasm, Malignant Thoracic Neoplasm
- Trial name
- NCT03868579
- Testing
- Biopsy, Medical Chart Review, Thoracoscopy
- Where
- 4 sites in United States, Cyprus
- Volunteers
- 97 people
- Sponsor
- M.D. Anderson Cancer Center
Pulmonary Segmentectomy
Fluorescence-navigated Thoracoscopy for Pulmonary Segmentectomy
Recently developed fluorescence-navigated thoracoscopy with indocyanine green (ICG) is being used for various kinds of pulmonary surgery, and several studies have reported the application of this novel technique in demarcation of…
- Trial name
- NCT04160884
- Testing
- Indocyanine Green Injection through Peripheral Vein
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Peking University People's Hospital
Reversal of Neuromuscular Blockade
Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis
The purpose of this study was to demonstrate in patients with myasthenia gravis (MG) undergoing thoracoscopic thymectomy faster recovery from a moderate neuromuscular block induced by rocuronium after reversal at reappearance of…
- Trial name
- NCT06436768
- Testing
- Sugammadex, Neostigmine
- Where
- 2 sites in China
- Volunteers
- 62 people
- Sponsor
- Beijing Tongren Hospital
Pain, Postoperative
Efficacy of Erector Spinae Plane Block for Postoperative Analgesia in Adult Patients Undergoing Thoracoscopy
The erector spinae plane block has been recently described as an effective analgesic postoperative pain treatment in case reports.
- Trial name
- NCT03454191
- Testing
- Erector spinae plane block, No injection
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Eric Albrecht
Solitary Pulmonary Nodule, Bronchial Neoplasms
ThoHSpEkt Thoracoscopic Ectomy of Radioactively Marked Pulmonary Nodules With Free-hand SPECT
Title ThoHSpEkt Study Design Pilot Study concerning the technical operative methods and a phase II study concerning the radiopharmaceutical (therapeutic-explorative study with an approved drug in a new indication) Location…
- Trial name
- ThoHSpEkt (NCT02050724)
- Testing
- Radioactive labelling of pulmonary nodules, CT guided radioactive labelling, Electromagnetic guided bronchoscopic radioactive labelling
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- Cantonal Hospital of St. Gallen
Postoperative Pain, Thoracic Neoplasms
Erector Spinae Block for Thoracoscopic Surgery
This randomized clinical trial compares the effects of the erector spinae plane block with levobupivacaine and 0,9% saline on postoperative pain intensity, and opioid consumptions following thoracoscopic pulmonary surgery.
- Trial name
- NCT04751552
- Testing
- Erector Spinae Plane Block (for postoperative pain relief)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- St. Antonius Hospital
Mesotheliomas Pleural, Malignant Pleural Mesothelioma
The IMmunotherapy Pleural 5-ALA PDT
Pilot study of the feasibility of an innovative multimodal treatment combining intrapleural photodynamic therapy with videothoracoscopy followed by adjuvant immunotherapy with anti-PD-1 Nivolumab antibodies in patients with…
- Trial name
- IMPALA (NCT04400539)
- Testing
- intrapleural photodynamic therapy with videothoracoscopy, Nivolumab Injection
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Lille
Lung Cancer
Cervical Video Assisted Thoracoscopic Surgery (C-VATS)
Although thoracic NOTES may not be ready for human trials, a new minimally invasive technique to access the pleural cavity and perform pleural, pulmonary and mediastinal procedures would be possible.
- Trial name
- CT0030 (NCT01440244)
- Testing
- Cervical mediastinoscopy
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Spontaneous Pneumothorax, Idiopathic Pneumothorax
Thoracoscopy for Idiopathic Pneumothorax in Children
The goal of this retrospective study is to describe the outcomes of spontaneous idiopathic pneumothorax treated by thoracoscopy with pleural abrasion and blebectomy.
- Conditions
- Spontaneous Pneumothorax, Idiopathic Pneumothorax, Bleb Lung, Child, Only
- Trial name
- THOPED (NCT06734442)
- Testing
- Video-Assisted Thoracoscopy with blebectomy and pleural abrasion
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Clermont-Ferrand
Esketamine Plus Dexmedetomidine Affect Postoperative Quality, Thoracoscopy
The Effect of Esketamine Combined With Dexmedetomidine on Postoperative Recovery Quality in Patients Undergoing Thoracoscopic Surgery
Brief Summary：Video-assisted thoracoscopic surgery (VATS) has a wide range of applications, including the diagnosis and treatment of lung cancer, and has gradually replaced traditional open thoracotomy.
- Conditions
- Esketamine Plus Dexmedetomidine Affect Postoperative Quality, Thoracoscopy, Lung Neoplasms
- Trial name
- NCT07125573
- Testing
- Saline Solution (NaCl 0,9%), Low-dose esketamine infusion, High-dose esketamine infusion
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Pleural Effusion, Pleural Diseases
Rigid Thoracoscopy Versus CT-Guided Pleural Needle Biopsy
The aim of this study is to compare the rigid thoracoscopy with CT-guided pleural needle biopsy by the diagnostic efficacy and safety in patients with pleural effusion.
- Trial name
- NCT00720954
- Testing
- Ct-guided pleural needle biopsy, Thoracoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Eskisehir Osmangazi University
Empyema
Medical Thoracoscopy in Treatment Outcomes of Empyema Management
To evaluate the efficacy of drainage achieved by thoracoscopy vs tube drainage alone. To compare clinical outcomes such as length of hospital stay, need for additional procedures, and treatment failure rates between the two…
- Trial name
- NCT06132997
- Testing
- Thoracoscopy procedure, Chest tube thoracostomy
- Volunteers
- 100 people
- Sponsor
- Hend Mohamed Sayed Mohamed
Lung Cancer, Lobectomy
Medicoeconomic Evaluation of Two Surgical Techniques for Lobectomy in the Lung Cancer
This is a national study that involves the participation of 600 lung cancer patients indicated that treatment is ablation of the pulmonary lobe. This technique is called lobectomy.
- Trial name
- LungSco01 (NCT02502318)
- Testing
- Video-thoracoscopy, thoracotomy
- Where
- 10 sites in France
- Volunteers
- 261 people
- Sponsor
- Centre Hospitalier Universitaire Dijon